Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AGN6_LEIIN

TriTrypDb:

LINF_160014500

Length:

297

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGN6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGN6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	192	194	PF00675	0.706
CLV_NRD_NRD_1	30	32	PF00675	0.631
CLV_NRD_NRD_1	87	89	PF00675	0.718
CLV_NRD_NRD_1	98	100	PF00675	0.592
CLV_PCSK_KEX2_1	191	193	PF00082	0.781
CLV_PCSK_KEX2_1	30	32	PF00082	0.635
CLV_PCSK_KEX2_1	87	89	PF00082	0.693
CLV_PCSK_KEX2_1	98	100	PF00082	0.523
CLV_PCSK_PC7_1	188	194	PF00082	0.699
CLV_PCSK_SKI1_1	139	143	PF00082	0.616
CLV_PCSK_SKI1_1	192	196	PF00082	0.754
CLV_PCSK_SKI1_1	77	81	PF00082	0.714
CLV_Separin_Metazoa	232	236	PF03568	0.513
DEG_APCC_KENBOX_2	260	264	PF00400	0.732
DEG_SPOP_SBC_1	267	271	PF00917	0.784
DOC_CYCLIN_RxL_1	74	83	PF00134	0.673
DOC_MAPK_gen_1	30	38	PF00069	0.648
DOC_PP1_RVXF_1	137	143	PF00149	0.605
DOC_USP7_MATH_1	134	138	PF00917	0.684
DOC_USP7_MATH_1	149	153	PF00917	0.599
DOC_USP7_MATH_1	267	271	PF00917	0.702
DOC_USP7_MATH_1	275	279	PF00917	0.607
DOC_USP7_MATH_1	289	293	PF00917	0.565
DOC_USP7_MATH_1	37	41	PF00917	0.621
DOC_WW_Pin1_4	285	290	PF00397	0.674
DOC_WW_Pin1_4	50	55	PF00397	0.686
LIG_14-3-3_CanoR_1	139	147	PF00244	0.665
LIG_14-3-3_CanoR_1	19	25	PF00244	0.683
LIG_BIR_II_1	1	5	PF00653	0.668
LIG_EH_1	31	35	PF12763	0.627
LIG_FHA_1	67	73	PF00498	0.646
LIG_FHA_2	178	184	PF00498	0.697
LIG_LIR_Apic_2	164	169	PF02991	0.552
LIG_LIR_Gen_1	104	110	PF02991	0.549
LIG_LIR_Nem_3	104	109	PF02991	0.552
LIG_PDZ_Class_3	292	297	PF00595	0.713
LIG_Pex14_1	102	106	PF04695	0.580
LIG_Rb_LxCxE_1	116	137	PF01857	0.566
LIG_SH2_CRK	166	170	PF00017	0.714
LIG_SH2_STAT5	227	230	PF00017	0.634
LIG_SH3_1	166	172	PF00018	0.718
LIG_SH3_3	166	172	PF00018	0.658
LIG_SH3_3	283	289	PF00018	0.656
LIG_SH3_3	83	89	PF00018	0.669
LIG_SUMO_SIM_par_1	34	41	PF11976	0.623
MOD_CK1_1	202	208	PF00069	0.685
MOD_CK1_1	253	259	PF00069	0.581
MOD_CK1_1	268	274	PF00069	0.733
MOD_CK1_1	288	294	PF00069	0.736
MOD_CK1_1	71	77	PF00069	0.726
MOD_CK2_1	177	183	PF00069	0.764
MOD_CK2_1	289	295	PF00069	0.570
MOD_Cter_Amidation	189	192	PF01082	0.674
MOD_GlcNHglycan	151	154	PF01048	0.695
MOD_GlcNHglycan	201	204	PF01048	0.805
MOD_GlcNHglycan	220	223	PF01048	0.764
MOD_GlcNHglycan	255	258	PF01048	0.710
MOD_GlcNHglycan	277	280	PF01048	0.746
MOD_GlcNHglycan	56	59	PF01048	0.715
MOD_GlcNHglycan	82	85	PF01048	0.718
MOD_GSK3_1	104	111	PF00069	0.537
MOD_GSK3_1	145	152	PF00069	0.605
MOD_GSK3_1	198	205	PF00069	0.749
MOD_GSK3_1	213	220	PF00069	0.528
MOD_GSK3_1	261	268	PF00069	0.719
MOD_GSK3_1	285	292	PF00069	0.753
MOD_GSK3_1	50	57	PF00069	0.719
MOD_GSK3_1	64	71	PF00069	0.521
MOD_N-GLC_1	217	222	PF02516	0.586
MOD_N-GLC_1	265	270	PF02516	0.757
MOD_NEK2_1	265	270	PF00069	0.732
MOD_NEK2_1	6	11	PF00069	0.638
MOD_NEK2_1	80	85	PF00069	0.679
MOD_OFUCOSY	64	70	PF10250	0.644
MOD_PIKK_1	104	110	PF00454	0.649
MOD_PIKK_1	213	219	PF00454	0.679
MOD_PIKK_1	250	256	PF00454	0.578
MOD_PK_1	68	74	PF00069	0.628
MOD_PKA_1	87	93	PF00069	0.683
MOD_PKA_2	18	24	PF00069	0.598
MOD_PKA_2	228	234	PF00069	0.569
MOD_PKA_2	87	93	PF00069	0.740
MOD_PKB_1	191	199	PF00069	0.661
MOD_Plk_1	261	267	PF00069	0.813
MOD_ProDKin_1	285	291	PF00069	0.672
MOD_ProDKin_1	50	56	PF00069	0.686
TRG_ER_diArg_1	118	121	PF00400	0.321
TRG_ER_diArg_1	191	193	PF00400	0.781
TRG_ER_diArg_1	86	88	PF00400	0.714
TRG_ER_diArg_1	98	100	PF00400	0.598

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P756	Leptomonas seymouri	35%	95%
A0A3S7WU02	Leishmania donovani	99%	100%
A4H8L3	Leishmania braziliensis	71%	100%
E9AQP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4QES9	Leishmania major	88%	100%