LeishMANIAdb
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60S acidic ribosomal protein P2

Quick info Annotations Function or PPIs Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
60S acidic ribosomal protein P2
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania infantum
UniProt:
E9AGM1_LEIIN
TriTrypDb:
Length:
111

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S acidic ribosomal P2

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 4
Pissara et al. yes yes: 24
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 14
NetGPI no yes: 0, no: 15
Cellular components
TermNameLevelCount
GO:0015934 large ribosomal subunit 4 16
GO:0022625 cytosolic large ribosomal subunit 5 16
GO:0032991 protein-containing complex 1 16
GO:0044391 ribosomal subunit 3 16
GO:1990904 ribonucleoprotein complex 2 16
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Phosphorylation

Promastigote: 80

Expansion

Sequence features

E9AGM1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGM1

Function

Biological processes
TermNameLevelCount
GO:0002182 cytoplasmic translational elongation 6 16
GO:0006414 translational elongation 5 16
GO:0008152 metabolic process 1 16
GO:0009058 biosynthetic process 2 16
GO:0009059 macromolecule biosynthetic process 4 16
GO:0009987 cellular process 1 16
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 16
GO:0043170 macromolecule metabolic process 3 16
GO:0044237 cellular metabolic process 2 16
GO:0044249 cellular biosynthetic process 3 16
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Molecular functions
TermNameLevelCount
GO:0003735 structural constituent of ribosome 2 16
GO:0005198 structural molecule activity 1 16
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
DOC_USP7_MATH_1 10 14 PF00917 0.389
DOC_USP7_MATH_1 17 21 PF00917 0.270
DOC_USP7_MATH_1 61 65 PF00917 0.452
DOC_USP7_MATH_1 67 71 PF00917 0.436
DOC_WW_Pin1_4 15 20 PF00397 0.500
LIG_BIR_II_1 1 5 PF00653 0.382
LIG_BIR_III_2 84 88 PF00653 0.437
LIG_FHA_1 1 7 PF00498 0.407
LIG_FHA_2 46 52 PF00498 0.437
LIG_FHA_2 90 96 PF00498 0.405
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HZR2 Leptomonas seymouri 49% 100%
A0A0S4JJB8 Bodo saltans 53% 100%
A0A1X0NVF0 Trypanosomatidae 67% 100%
A0A1X0P2R9 Trypanosomatidae 48% 100%
A0A3Q8ICC2 Leishmania donovani 99% 100%
A0A3Q8IG52 Leishmania donovani 51% 100%
A0A422NR90 Trypanosoma rangeli 69% 100%
A4H884 Leishmania braziliensis 82% 100%
A4I5Z9 Leishmania infantum 52% 97%
A4I600 Leishmania infantum 51% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS