Calpain catalytic domain-containing protein

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

tb-292 membrane associated protein-like protein

Species:

Leishmania infantum

UniProt:

E9AGL6_LEIIN

TriTrypDb:

LINF_150012100

Length:

2653

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Phosphorylation

Promastigote: 187

Expansion

Sequence features

E9AGL6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGL6

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	142	146	PF00656	0.414
CLV_C14_Caspase3-7	1642	1646	PF00656	0.652
CLV_C14_Caspase3-7	1750	1754	PF00656	0.857
CLV_C14_Caspase3-7	2193	2197	PF00656	0.498
CLV_C14_Caspase3-7	2311	2315	PF00656	0.509
CLV_C14_Caspase3-7	2502	2506	PF00656	0.661
CLV_C14_Caspase3-7	580	584	PF00656	0.345
CLV_C14_Caspase3-7	870	874	PF00656	0.693
CLV_NRD_NRD_1	1222	1224	PF00675	0.547
CLV_NRD_NRD_1	1266	1268	PF00675	0.534

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2S3	Leptomonas seymouri	55%	100%
A0A1X0NTQ6	Trypanosomatidae	30%	100%
A4H818	Leishmania braziliensis	76%	100%

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