LeishMANIAdb
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Putative mitochondrial DNA polymerase I protein C

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative mitochondrial DNA polymerase I protein C
Gene product:
mitochondrial DNA polymerase I protein C - putative
Species:
Leishmania infantum
UniProt:
E9AGL3_LEIIN
TriTrypDb:
LINF_140015300
Length:
1548

Annotations

Annotations by Jardim et al.

DNA replication, mitochondrial DNA polymerase I C

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0009295 nucleoid 2 1
GO:0042645 mitochondrial nucleoid 3 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9AGL3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGL3

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 10
GO:0006259 DNA metabolic process 4 10
GO:0006260 DNA replication 5 10
GO:0006261 DNA-templated DNA replication 6 10
GO:0006725 cellular aromatic compound metabolic process 3 10
GO:0006807 nitrogen compound metabolic process 2 10
GO:0008152 metabolic process 1 10
GO:0009987 cellular process 1 10
GO:0034641 cellular nitrogen compound metabolic process 3 10
GO:0043170 macromolecule metabolic process 3 10
GO:0044237 cellular metabolic process 2 10
GO:0044238 primary metabolic process 2 10
GO:0044260 obsolete cellular macromolecule metabolic process 3 10
GO:0046483 heterocycle metabolic process 3 10
GO:0071704 organic substance metabolic process 2 10
GO:0090304 nucleic acid metabolic process 4 10
GO:1901360 organic cyclic compound metabolic process 3 10
GO:0006264 mitochondrial DNA replication 6 1
GO:0006281 DNA repair 5 1
GO:0006302 double-strand break repair 6 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
GO:0032042 mitochondrial DNA metabolic process 5 1
GO:0033554 cellular response to stress 3 1
GO:0050896 response to stimulus 1 1
GO:0051716 cellular response to stimulus 2 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 10
GO:0003677 DNA binding 4 10
GO:0003824 catalytic activity 1 10
GO:0003887 DNA-directed DNA polymerase activity 5 10
GO:0005488 binding 1 10
GO:0016740 transferase activity 2 10
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 10
GO:0016779 nucleotidyltransferase activity 4 10
GO:0034061 DNA polymerase activity 4 10
GO:0097159 organic cyclic compound binding 2 10
GO:0140097 catalytic activity, acting on DNA 3 10
GO:0140640 catalytic activity, acting on a nucleic acid 2 10
GO:1901363 heterocyclic compound binding 2 10

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1175 1179 PF00656 0.511
CLV_C14_Caspase3-7 1300 1304 PF00656 0.531
CLV_C14_Caspase3-7 35 39 PF00656 0.757
CLV_MEL_PAP_1 1265 1271 PF00089 0.290
CLV_NRD_NRD_1 1165 1167 PF00675 0.627
CLV_NRD_NRD_1 1262 1264 PF00675 0.298
CLV_NRD_NRD_1 1324 1326 PF00675 0.308
CLV_NRD_NRD_1 1417 1419 PF00675 0.290
CLV_NRD_NRD_1 1442 1444 PF00675 0.332
CLV_NRD_NRD_1 1474 1476 PF00675 0.302
CLV_NRD_NRD_1 288 290 PF00675 0.722
CLV_NRD_NRD_1 371 373 PF00675 0.592
CLV_NRD_NRD_1 440 442 PF00675 0.623
CLV_NRD_NRD_1 551 553 PF00675 0.612
CLV_NRD_NRD_1 642 644 PF00675 0.468
CLV_NRD_NRD_1 868 870 PF00675 0.531
CLV_NRD_NRD_1 977 979 PF00675 0.779
CLV_PCSK_KEX2_1 1165 1167 PF00082 0.627
CLV_PCSK_KEX2_1 1262 1264 PF00082 0.298
CLV_PCSK_KEX2_1 1417 1419 PF00082 0.290
CLV_PCSK_KEX2_1 1476 1478 PF00082 0.303
CLV_PCSK_KEX2_1 287 289 PF00082 0.703
CLV_PCSK_KEX2_1 440 442 PF00082 0.623
CLV_PCSK_KEX2_1 551 553 PF00082 0.612
CLV_PCSK_KEX2_1 635 637 PF00082 0.375
CLV_PCSK_KEX2_1 642 644 PF00082 0.406
CLV_PCSK_KEX2_1 868 870 PF00082 0.568
CLV_PCSK_KEX2_1 879 881 PF00082 0.580
CLV_PCSK_KEX2_1 983 985 PF00082 0.762
CLV_PCSK_PC1ET2_1 1476 1478 PF00082 0.308
CLV_PCSK_PC1ET2_1 635 637 PF00082 0.380
CLV_PCSK_PC1ET2_1 879 881 PF00082 0.597
CLV_PCSK_PC1ET2_1 983 985 PF00082 0.765
CLV_PCSK_SKI1_1 1002 1006 PF00082 0.463
CLV_PCSK_SKI1_1 1029 1033 PF00082 0.567
CLV_PCSK_SKI1_1 1123 1127 PF00082 0.599
CLV_PCSK_SKI1_1 1165 1169 PF00082 0.604
CLV_PCSK_SKI1_1 1221 1225 PF00082 0.290
CLV_PCSK_SKI1_1 1325 1329 PF00082 0.305
CLV_PCSK_SKI1_1 1482 1486 PF00082 0.290
CLV_PCSK_SKI1_1 260 264 PF00082 0.582
CLV_PCSK_SKI1_1 375 379 PF00082 0.687
CLV_PCSK_SKI1_1 635 639 PF00082 0.372
CLV_PCSK_SKI1_1 648 652 PF00082 0.380
CLV_PCSK_SKI1_1 680 684 PF00082 0.460
CLV_PCSK_SKI1_1 77 81 PF00082 0.597
CLV_PCSK_SKI1_1 958 962 PF00082 0.567
DEG_APCC_DBOX_1 1505 1513 PF00400 0.508
DEG_APCC_DBOX_1 310 318 PF00400 0.696
DEG_APCC_DBOX_1 395 403 PF00400 0.714
DEG_APCC_DBOX_1 867 875 PF00400 0.465
DEG_Nend_UBRbox_2 1 3 PF02207 0.660
DEG_SPOP_SBC_1 298 302 PF00917 0.694
DOC_ANK_TNKS_1 989 996 PF00023 0.677
DOC_CKS1_1 1119 1124 PF01111 0.611
DOC_CKS1_1 1130 1135 PF01111 0.724
DOC_CKS1_1 1154 1159 PF01111 0.486
DOC_CYCLIN_RxL_1 1205 1216 PF00134 0.594
DOC_CYCLIN_RxL_1 633 644 PF00134 0.381
DOC_CYCLIN_RxL_1 674 687 PF00134 0.580
DOC_CYCLIN_RxL_1 955 965 PF00134 0.616
DOC_CYCLIN_yClb5_NLxxxL_5 396 403 PF00134 0.711
DOC_CYCLIN_yCln2_LP_2 1422 1428 PF00134 0.508
DOC_CYCLIN_yCln2_LP_2 1529 1535 PF00134 0.490
DOC_MAPK_gen_1 126 135 PF00069 0.662
DOC_MAPK_gen_1 1328 1338 PF00069 0.490
DOC_MAPK_gen_1 306 316 PF00069 0.604
DOC_MAPK_gen_1 372 382 PF00069 0.571
DOC_MAPK_gen_1 533 542 PF00069 0.511
DOC_MAPK_gen_1 621 630 PF00069 0.557
DOC_MAPK_gen_1 635 641 PF00069 0.370
DOC_MAPK_gen_1 87 96 PF00069 0.710
DOC_MAPK_JIP1_4 393 399 PF00069 0.729
DOC_MAPK_MEF2A_6 137 145 PF00069 0.666
DOC_MAPK_MEF2A_6 597 606 PF00069 0.553
DOC_MAPK_MEF2A_6 87 96 PF00069 0.667
DOC_MAPK_MEF2A_6 921 929 PF00069 0.561
DOC_MIT_MIM_1 71 81 PF04212 0.612
DOC_PP1_RVXF_1 1048 1054 PF00149 0.485
DOC_PP1_RVXF_1 126 133 PF00149 0.702
DOC_PP1_RVXF_1 410 416 PF00149 0.670
DOC_PP1_RVXF_1 634 641 PF00149 0.369
DOC_PP1_RVXF_1 780 786 PF00149 0.526
DOC_PP2B_LxvP_1 1529 1532 PF13499 0.490
DOC_PP4_FxxP_1 1060 1063 PF00568 0.551
DOC_PP4_FxxP_1 1429 1432 PF00568 0.508
DOC_PP4_FxxP_1 341 344 PF00568 0.590
DOC_PP4_FxxP_1 451 454 PF00568 0.689
DOC_PP4_FxxP_1 599 602 PF00568 0.434
DOC_PP4_FxxP_1 70 73 PF00568 0.678
DOC_PP4_FxxP_1 785 788 PF00568 0.498
DOC_PP4_MxPP_1 577 580 PF00568 0.587
DOC_USP7_MATH_1 1054 1058 PF00917 0.399
DOC_USP7_MATH_1 1107 1111 PF00917 0.474
DOC_USP7_MATH_1 1125 1129 PF00917 0.440
DOC_USP7_MATH_1 1131 1135 PF00917 0.690
DOC_USP7_MATH_1 1353 1357 PF00917 0.551
DOC_USP7_MATH_1 1432 1436 PF00917 0.508
DOC_USP7_MATH_1 159 163 PF00917 0.673
DOC_USP7_MATH_1 171 175 PF00917 0.723
DOC_USP7_MATH_1 298 302 PF00917 0.650
DOC_USP7_MATH_1 361 365 PF00917 0.578
DOC_USP7_MATH_1 406 410 PF00917 0.672
DOC_USP7_MATH_1 429 433 PF00917 0.690
DOC_USP7_MATH_1 49 53 PF00917 0.795
DOC_USP7_MATH_1 502 506 PF00917 0.629
DOC_USP7_MATH_1 531 535 PF00917 0.571
DOC_USP7_MATH_1 56 60 PF00917 0.727
DOC_USP7_MATH_1 817 821 PF00917 0.639
DOC_USP7_MATH_1 962 966 PF00917 0.644
DOC_USP7_UBL2_3 1381 1385 PF12436 0.591
DOC_USP7_UBL2_3 200 204 PF12436 0.756
DOC_USP7_UBL2_3 588 592 PF12436 0.547
DOC_USP7_UBL2_3 979 983 PF12436 0.761
DOC_WW_Pin1_4 1118 1123 PF00397 0.608
DOC_WW_Pin1_4 1129 1134 PF00397 0.703
DOC_WW_Pin1_4 1153 1158 PF00397 0.497
DOC_WW_Pin1_4 1185 1190 PF00397 0.577
DOC_WW_Pin1_4 1246 1251 PF00397 0.490
DOC_WW_Pin1_4 147 152 PF00397 0.669
DOC_WW_Pin1_4 69 74 PF00397 0.636
DOC_WW_Pin1_4 784 789 PF00397 0.512
LIG_14-3-3_CanoR_1 100 104 PF00244 0.686
LIG_14-3-3_CanoR_1 1088 1092 PF00244 0.599
LIG_14-3-3_CanoR_1 1127 1131 PF00244 0.625
LIG_14-3-3_CanoR_1 1145 1154 PF00244 0.553
LIG_14-3-3_CanoR_1 1182 1186 PF00244 0.527
LIG_14-3-3_CanoR_1 1205 1213 PF00244 0.464
LIG_14-3-3_CanoR_1 1244 1252 PF00244 0.490
LIG_14-3-3_CanoR_1 1311 1315 PF00244 0.508
LIG_14-3-3_CanoR_1 137 141 PF00244 0.666
LIG_14-3-3_CanoR_1 1403 1408 PF00244 0.508
LIG_14-3-3_CanoR_1 1443 1447 PF00244 0.591
LIG_14-3-3_CanoR_1 412 416 PF00244 0.653
LIG_14-3-3_CanoR_1 440 444 PF00244 0.657
LIG_14-3-3_CanoR_1 490 498 PF00244 0.708
LIG_14-3-3_CanoR_1 499 507 PF00244 0.580
LIG_14-3-3_CanoR_1 642 646 PF00244 0.504
LIG_14-3-3_CanoR_1 715 721 PF00244 0.454
LIG_14-3-3_CanoR_1 77 82 PF00244 0.594
LIG_14-3-3_CanoR_1 815 823 PF00244 0.601
LIG_14-3-3_CanoR_1 868 872 PF00244 0.503
LIG_14-3-3_CanoR_1 880 884 PF00244 0.514
LIG_Actin_WH2_2 1298 1313 PF00022 0.508
LIG_Actin_WH2_2 61 79 PF00022 0.616
LIG_Actin_WH2_2 627 644 PF00022 0.377
LIG_Actin_WH2_2 675 693 PF00022 0.592
LIG_AP_GAE_1 1071 1077 PF02883 0.706
LIG_APCC_ABBA_1 1211 1216 PF00400 0.449
LIG_APCC_ABBAyCdc20_2 1210 1216 PF00400 0.483
LIG_BIR_III_4 38 42 PF00653 0.585
LIG_BIR_III_4 466 470 PF00653 0.719
LIG_BRCT_BRCA1_1 1056 1060 PF00533 0.464
LIG_BRCT_BRCA1_1 431 435 PF00533 0.733
LIG_Clathr_ClatBox_1 67 71 PF01394 0.613
LIG_CtBP_PxDLS_1 344 348 PF00389 0.731
LIG_CtBP_PxDLS_1 73 77 PF00389 0.585
LIG_deltaCOP1_diTrp_1 131 136 PF00928 0.667
LIG_deltaCOP1_diTrp_1 221 226 PF00928 0.557
LIG_deltaCOP1_diTrp_1 310 316 PF00928 0.593
LIG_EH_1 554 558 PF12763 0.494
LIG_EH1_1 721 729 PF00400 0.391
LIG_eIF4E_1 816 822 PF01652 0.640
LIG_EVH1_1 1060 1064 PF00568 0.566
LIG_FHA_1 1019 1025 PF00498 0.455
LIG_FHA_1 1182 1188 PF00498 0.503
LIG_FHA_1 1190 1196 PF00498 0.489
LIG_FHA_1 1240 1246 PF00498 0.480
LIG_FHA_1 1359 1365 PF00498 0.495
LIG_FHA_1 1389 1395 PF00498 0.508
LIG_FHA_1 1421 1427 PF00498 0.511
LIG_FHA_1 210 216 PF00498 0.600
LIG_FHA_1 288 294 PF00498 0.691
LIG_FHA_1 325 331 PF00498 0.679
LIG_FHA_1 398 404 PF00498 0.566
LIG_FHA_1 56 62 PF00498 0.686
LIG_FHA_1 591 597 PF00498 0.621
LIG_FHA_1 607 613 PF00498 0.505
LIG_FHA_1 750 756 PF00498 0.551
LIG_FHA_1 888 894 PF00498 0.433
LIG_FHA_2 106 112 PF00498 0.595
LIG_FHA_2 1119 1125 PF00498 0.507
LIG_FHA_2 1363 1369 PF00498 0.508
LIG_FHA_2 1486 1492 PF00498 0.490
LIG_FHA_2 704 710 PF00498 0.435
LIG_FHA_2 861 867 PF00498 0.585
LIG_FHA_2 914 920 PF00498 0.629
LIG_FHA_2 995 1001 PF00498 0.524
LIG_GBD_Chelix_1 1457 1465 PF00786 0.290
LIG_HCF-1_HBM_1 1377 1380 PF13415 0.561
LIG_LIR_Apic_2 1057 1063 PF02991 0.583
LIG_LIR_Apic_2 338 344 PF02991 0.613
LIG_LIR_Apic_2 450 454 PF02991 0.692
LIG_LIR_Apic_2 598 602 PF02991 0.478
LIG_LIR_Apic_2 69 73 PF02991 0.678
LIG_LIR_Gen_1 106 116 PF02991 0.594
LIG_LIR_Gen_1 1071 1082 PF02991 0.701
LIG_LIR_Gen_1 1196 1206 PF02991 0.523
LIG_LIR_Gen_1 1277 1288 PF02991 0.490
LIG_LIR_Gen_1 1306 1315 PF02991 0.490
LIG_LIR_Gen_1 131 140 PF02991 0.630
LIG_LIR_Gen_1 1318 1327 PF02991 0.485
LIG_LIR_Gen_1 1332 1342 PF02991 0.457
LIG_LIR_Gen_1 189 197 PF02991 0.568
LIG_LIR_Gen_1 31 42 PF02991 0.755
LIG_LIR_Gen_1 363 371 PF02991 0.608
LIG_LIR_Gen_1 408 418 PF02991 0.603
LIG_LIR_Nem_3 106 112 PF02991 0.597
LIG_LIR_Nem_3 1071 1077 PF02991 0.625
LIG_LIR_Nem_3 1188 1193 PF02991 0.497
LIG_LIR_Nem_3 1196 1201 PF02991 0.357
LIG_LIR_Nem_3 1277 1283 PF02991 0.501
LIG_LIR_Nem_3 1306 1310 PF02991 0.500
LIG_LIR_Nem_3 131 135 PF02991 0.622
LIG_LIR_Nem_3 1318 1323 PF02991 0.470
LIG_LIR_Nem_3 1332 1338 PF02991 0.490
LIG_LIR_Nem_3 1377 1383 PF02991 0.490
LIG_LIR_Nem_3 139 143 PF02991 0.583
LIG_LIR_Nem_3 1424 1430 PF02991 0.565
LIG_LIR_Nem_3 184 190 PF02991 0.650
LIG_LIR_Nem_3 221 226 PF02991 0.538
LIG_LIR_Nem_3 31 37 PF02991 0.789
LIG_LIR_Nem_3 310 315 PF02991 0.594
LIG_LIR_Nem_3 363 368 PF02991 0.587
LIG_LIR_Nem_3 408 413 PF02991 0.554
LIG_LIR_Nem_3 414 418 PF02991 0.588
LIG_LIR_Nem_3 432 438 PF02991 0.641
LIG_LIR_Nem_3 806 811 PF02991 0.720
LIG_LYPXL_SIV_4 837 845 PF13949 0.608
LIG_PAM2_1 214 226 PF00658 0.554
LIG_PCNA_PIPBox_1 1517 1526 PF02747 0.561
LIG_PCNA_yPIPBox_3 1511 1524 PF02747 0.563
LIG_PCNA_yPIPBox_3 715 728 PF02747 0.494
LIG_PDZ_Class_2 1543 1548 PF00595 0.641
LIG_Pex14_1 132 136 PF04695 0.567
LIG_Pex14_1 312 316 PF04695 0.590
LIG_Pex14_1 658 662 PF04695 0.365
LIG_Pex14_2 105 109 PF04695 0.574
LIG_Pex14_2 1070 1074 PF04695 0.610
LIG_Pex14_2 136 140 PF04695 0.605
LIG_SH2_CRK 1387 1391 PF00017 0.490
LIG_SH2_CRK 190 194 PF00017 0.624
LIG_SH2_NCK_1 1387 1391 PF00017 0.591
LIG_SH2_NCK_1 34 38 PF00017 0.759
LIG_SH2_PTP2 1335 1338 PF00017 0.490
LIG_SH2_SRC 1320 1323 PF00017 0.490
LIG_SH2_SRC 354 357 PF00017 0.572
LIG_SH2_STAP1 1320 1324 PF00017 0.490
LIG_SH2_STAP1 219 223 PF00017 0.577
LIG_SH2_STAP1 662 666 PF00017 0.362
LIG_SH2_STAP1 704 708 PF00017 0.476
LIG_SH2_STAT3 1452 1455 PF00017 0.490
LIG_SH2_STAT3 436 439 PF00017 0.746
LIG_SH2_STAT3 516 519 PF00017 0.554
LIG_SH2_STAT3 704 707 PF00017 0.478
LIG_SH2_STAT5 129 132 PF00017 0.621
LIG_SH2_STAT5 1335 1338 PF00017 0.476
LIG_SH2_STAT5 1428 1431 PF00017 0.490
LIG_SH2_STAT5 354 357 PF00017 0.572
LIG_SH2_STAT5 538 541 PF00017 0.454
LIG_SH2_STAT5 665 668 PF00017 0.366
LIG_SH2_STAT5 748 751 PF00017 0.552
LIG_SH2_STAT5 911 914 PF00017 0.475
LIG_SH2_STAT5 95 98 PF00017 0.741
LIG_SH3_1 1058 1064 PF00018 0.545
LIG_SH3_1 807 813 PF00018 0.638
LIG_SH3_2 810 815 PF14604 0.666
LIG_SH3_3 1058 1064 PF00018 0.575
LIG_SH3_3 1116 1122 PF00018 0.557
LIG_SH3_3 162 168 PF00018 0.740
LIG_SH3_3 314 320 PF00018 0.600
LIG_SH3_3 39 45 PF00018 0.704
LIG_SH3_3 423 429 PF00018 0.635
LIG_SH3_3 452 458 PF00018 0.696
LIG_SH3_3 601 607 PF00018 0.545
LIG_SH3_3 608 614 PF00018 0.535
LIG_SH3_3 807 813 PF00018 0.638
LIG_SH3_3 91 97 PF00018 0.709
LIG_SH3_3 912 918 PF00018 0.529
LIG_SUMO_SIM_anti_2 1281 1287 PF11976 0.490
LIG_SUMO_SIM_anti_2 212 217 PF11976 0.643
LIG_SUMO_SIM_anti_2 890 896 PF11976 0.384
LIG_SUMO_SIM_par_1 1003 1008 PF11976 0.439
LIG_SUMO_SIM_par_1 1191 1196 PF11976 0.531
LIG_SUMO_SIM_par_1 343 349 PF11976 0.616
LIG_SUMO_SIM_par_1 562 567 PF11976 0.477
LIG_SUMO_SIM_par_1 940 945 PF11976 0.561
LIG_SUMO_SIM_par_1 959 965 PF11976 0.549
LIG_TRAF2_1 1256 1259 PF00917 0.508
LIG_TRAF2_1 1365 1368 PF00917 0.506
LIG_TRAF2_1 527 530 PF00917 0.600
LIG_TRAF2_2 1063 1068 PF00917 0.637
LIG_TYR_ITIM 1426 1431 PF00017 0.374
LIG_TYR_ITSM 30 37 PF00017 0.791
LIG_UBA3_1 1151 1159 PF00899 0.552
LIG_WRC_WIRS_1 1344 1349 PF05994 0.444
LIG_WRC_WIRS_1 407 412 PF05994 0.596
LIG_WRC_WIRS_1 448 453 PF05994 0.645
LIG_WRC_WIRS_1 647 652 PF05994 0.518
MOD_CDC14_SPxK_1 1188 1191 PF00782 0.591
MOD_CDK_SPK_2 1118 1123 PF00069 0.608
MOD_CDK_SPxK_1 1153 1159 PF00069 0.517
MOD_CDK_SPxK_1 1185 1191 PF00069 0.583
MOD_CK1_1 1069 1075 PF00069 0.658
MOD_CK1_1 1080 1086 PF00069 0.524
MOD_CK1_1 1110 1116 PF00069 0.541
MOD_CK1_1 1129 1135 PF00069 0.712
MOD_CK1_1 1172 1178 PF00069 0.589
MOD_CK1_1 1196 1202 PF00069 0.518
MOD_CK1_1 1246 1252 PF00069 0.344
MOD_CK1_1 1313 1319 PF00069 0.369
MOD_CK1_1 1356 1362 PF00069 0.485
MOD_CK1_1 1388 1394 PF00069 0.485
MOD_CK1_1 1539 1545 PF00069 0.485
MOD_CK1_1 278 284 PF00069 0.637
MOD_CK1_1 401 407 PF00069 0.594
MOD_CK1_1 411 417 PF00069 0.569
MOD_CK1_1 744 750 PF00069 0.551
MOD_CK1_1 857 863 PF00069 0.635
MOD_CK1_1 965 971 PF00069 0.716
MOD_CK2_1 1278 1284 PF00069 0.356
MOD_CK2_1 1362 1368 PF00069 0.344
MOD_CK2_1 1539 1545 PF00069 0.339
MOD_CK2_1 343 349 PF00069 0.652
MOD_CK2_1 357 363 PF00069 0.477
MOD_CK2_1 447 453 PF00069 0.648
MOD_CK2_1 703 709 PF00069 0.347
MOD_CK2_1 913 919 PF00069 0.568
MOD_CK2_1 965 971 PF00069 0.670
MOD_Cter_Amidation 981 984 PF01082 0.773
MOD_GlcNHglycan 1085 1088 PF01048 0.472
MOD_GlcNHglycan 113 116 PF01048 0.581
MOD_GlcNHglycan 1134 1137 PF01048 0.763
MOD_GlcNHglycan 1171 1174 PF01048 0.557
MOD_GlcNHglycan 1198 1201 PF01048 0.489
MOD_GlcNHglycan 151 154 PF01048 0.539
MOD_GlcNHglycan 1538 1541 PF01048 0.485
MOD_GlcNHglycan 248 251 PF01048 0.702
MOD_GlcNHglycan 252 255 PF01048 0.702
MOD_GlcNHglycan 280 283 PF01048 0.635
MOD_GlcNHglycan 301 304 PF01048 0.661
MOD_GlcNHglycan 317 320 PF01048 0.509
MOD_GlcNHglycan 33 37 PF01048 0.779
MOD_GlcNHglycan 359 362 PF01048 0.614
MOD_GlcNHglycan 432 435 PF01048 0.737
MOD_GlcNHglycan 493 496 PF01048 0.636
MOD_GlcNHglycan 52 55 PF01048 0.717
MOD_GlcNHglycan 543 546 PF01048 0.483
MOD_GlcNHglycan 557 560 PF01048 0.503
MOD_GlcNHglycan 565 569 PF01048 0.417
MOD_GlcNHglycan 58 61 PF01048 0.722
MOD_GlcNHglycan 852 855 PF01048 0.661
MOD_GlcNHglycan 857 860 PF01048 0.649
MOD_GlcNHglycan 964 967 PF01048 0.699
MOD_GlcNHglycan 979 982 PF01048 0.690
MOD_GSK3_1 1014 1021 PF00069 0.513
MOD_GSK3_1 1072 1079 PF00069 0.697
MOD_GSK3_1 1083 1090 PF00069 0.550
MOD_GSK3_1 1110 1117 PF00069 0.460
MOD_GSK3_1 1125 1132 PF00069 0.518
MOD_GSK3_1 1181 1188 PF00069 0.509
MOD_GSK3_1 1189 1196 PF00069 0.493
MOD_GSK3_1 120 127 PF00069 0.567
MOD_GSK3_1 1239 1246 PF00069 0.349
MOD_GSK3_1 1353 1360 PF00069 0.348
MOD_GSK3_1 1403 1410 PF00069 0.436
MOD_GSK3_1 246 253 PF00069 0.693
MOD_GSK3_1 293 300 PF00069 0.691
MOD_GSK3_1 320 327 PF00069 0.695
MOD_GSK3_1 357 364 PF00069 0.590
MOD_GSK3_1 397 404 PF00069 0.567
MOD_GSK3_1 45 52 PF00069 0.723
MOD_GSK3_1 498 505 PF00069 0.649
MOD_GSK3_1 541 548 PF00069 0.537
MOD_GSK3_1 674 681 PF00069 0.475
MOD_GSK3_1 711 718 PF00069 0.502
MOD_GSK3_1 850 857 PF00069 0.697
MOD_GSK3_1 961 968 PF00069 0.692
MOD_GSK3_1 973 980 PF00069 0.806
MOD_LATS_1 1012 1018 PF00433 0.578
MOD_N-GLC_1 1080 1085 PF02516 0.636
MOD_N-GLC_1 397 402 PF02516 0.674
MOD_NEK2_1 1005 1010 PF00069 0.426
MOD_NEK2_1 1018 1023 PF00069 0.438
MOD_NEK2_1 1077 1082 PF00069 0.741
MOD_NEK2_1 1126 1131 PF00069 0.604
MOD_NEK2_1 1264 1269 PF00069 0.344
MOD_NEK2_1 1310 1315 PF00069 0.361
MOD_NEK2_1 136 141 PF00069 0.604
MOD_NEK2_1 1407 1412 PF00069 0.439
MOD_NEK2_1 1485 1490 PF00069 0.344
MOD_NEK2_1 186 191 PF00069 0.624
MOD_NEK2_1 276 281 PF00069 0.704
MOD_NEK2_1 297 302 PF00069 0.737
MOD_NEK2_1 397 402 PF00069 0.613
MOD_NEK2_1 498 503 PF00069 0.591
MOD_NEK2_1 540 545 PF00069 0.487
MOD_NEK2_1 570 575 PF00069 0.526
MOD_NEK2_1 641 646 PF00069 0.421
MOD_NEK2_1 678 683 PF00069 0.464
MOD_NEK2_1 690 695 PF00069 0.522
MOD_NEK2_1 749 754 PF00069 0.521
MOD_NEK2_1 769 774 PF00069 0.284
MOD_NEK2_1 961 966 PF00069 0.659
MOD_NEK2_2 817 822 PF00069 0.590
MOD_PIKK_1 1110 1116 PF00454 0.541
MOD_PIKK_1 1126 1132 PF00454 0.660
MOD_PIKK_1 1244 1250 PF00454 0.344
MOD_PIKK_1 1278 1284 PF00454 0.344
MOD_PIKK_1 1513 1519 PF00454 0.444
MOD_PIKK_1 384 390 PF00454 0.659
MOD_PIKK_1 401 407 PF00454 0.658
MOD_PIKK_1 515 521 PF00454 0.601
MOD_PIKK_1 703 709 PF00454 0.433
MOD_PIKK_1 741 747 PF00454 0.485
MOD_PIKK_1 769 775 PF00454 0.559
MOD_PIKK_1 942 948 PF00454 0.506
MOD_PKA_1 287 293 PF00069 0.700
MOD_PKA_1 879 885 PF00069 0.574
MOD_PKA_2 1087 1093 PF00069 0.544
MOD_PKA_2 1126 1132 PF00069 0.617
MOD_PKA_2 1144 1150 PF00069 0.581
MOD_PKA_2 1181 1187 PF00069 0.507
MOD_PKA_2 1204 1210 PF00069 0.453
MOD_PKA_2 1243 1249 PF00069 0.344
MOD_PKA_2 1310 1316 PF00069 0.394
MOD_PKA_2 136 142 PF00069 0.664
MOD_PKA_2 1442 1448 PF00069 0.401
MOD_PKA_2 287 293 PF00069 0.686
MOD_PKA_2 411 417 PF00069 0.657
MOD_PKA_2 439 445 PF00069 0.621
MOD_PKA_2 498 504 PF00069 0.685
MOD_PKA_2 641 647 PF00069 0.392
MOD_PKA_2 867 873 PF00069 0.527
MOD_PKA_2 879 885 PF00069 0.490
MOD_PKA_2 977 983 PF00069 0.765
MOD_PKA_2 99 105 PF00069 0.691
MOD_Plk_1 105 111 PF00069 0.670
MOD_Plk_1 1080 1086 PF00069 0.615
MOD_Plk_1 1193 1199 PF00069 0.432
MOD_Plk_1 1278 1284 PF00069 0.344
MOD_Plk_1 1407 1413 PF00069 0.444
MOD_Plk_1 32 38 PF00069 0.754
MOD_Plk_1 397 403 PF00069 0.672
MOD_Plk_1 678 684 PF00069 0.449
MOD_Plk_1 789 795 PF00069 0.461
MOD_Plk_2-3 1044 1050 PF00069 0.602
MOD_Plk_4 1014 1020 PF00069 0.516
MOD_Plk_4 1107 1113 PF00069 0.481
MOD_Plk_4 1114 1120 PF00069 0.463
MOD_Plk_4 1181 1187 PF00069 0.531
MOD_Plk_4 1193 1199 PF00069 0.370
MOD_Plk_4 1310 1316 PF00069 0.369
MOD_Plk_4 136 142 PF00069 0.603
MOD_Plk_4 1385 1391 PF00069 0.485
MOD_Plk_4 1407 1413 PF00069 0.491
MOD_Plk_4 234 240 PF00069 0.708
MOD_Plk_4 398 404 PF00069 0.595
MOD_Plk_4 447 453 PF00069 0.634
MOD_Plk_4 744 750 PF00069 0.551
MOD_Plk_4 790 796 PF00069 0.453
MOD_Plk_4 817 823 PF00069 0.584
MOD_ProDKin_1 1118 1124 PF00069 0.604
MOD_ProDKin_1 1129 1135 PF00069 0.712
MOD_ProDKin_1 1153 1159 PF00069 0.502
MOD_ProDKin_1 1185 1191 PF00069 0.583
MOD_ProDKin_1 1246 1252 PF00069 0.344
MOD_ProDKin_1 147 153 PF00069 0.667
MOD_ProDKin_1 69 75 PF00069 0.635
MOD_ProDKin_1 784 790 PF00069 0.509
MOD_SUMO_for_1 1256 1259 PF00179 0.485
MOD_SUMO_for_1 1327 1330 PF00179 0.380
MOD_SUMO_for_1 1533 1536 PF00179 0.401
MOD_SUMO_for_1 419 422 PF00179 0.670
MOD_SUMO_for_1 587 590 PF00179 0.522
MOD_SUMO_rev_2 123 127 PF00179 0.576
MOD_SUMO_rev_2 1438 1446 PF00179 0.369
MOD_SUMO_rev_2 221 226 PF00179 0.587
MOD_SUMO_rev_2 590 599 PF00179 0.559
MOD_SUMO_rev_2 965 975 PF00179 0.688
TRG_DiLeu_BaEn_1 1368 1373 PF01217 0.344
TRG_DiLeu_BaEn_1 1481 1486 PF01217 0.444
TRG_DiLeu_BaEn_1 625 630 PF01217 0.490
TRG_DiLeu_BaEn_2 594 600 PF01217 0.569
TRG_DiLeu_BaEn_3 221 227 PF01217 0.658
TRG_DiLeu_BaLyEn_6 1159 1164 PF01217 0.529
TRG_DiLeu_BaLyEn_6 1260 1265 PF01217 0.369
TRG_DiLeu_BaLyEn_6 1397 1402 PF01217 0.344
TRG_DiLeu_BaLyEn_6 503 508 PF01217 0.643
TRG_DiLeu_LyEn_5 1368 1373 PF01217 0.344
TRG_ENDOCYTIC_2 1190 1193 PF00928 0.578
TRG_ENDOCYTIC_2 1280 1283 PF00928 0.344
TRG_ENDOCYTIC_2 1320 1323 PF00928 0.341
TRG_ENDOCYTIC_2 1335 1338 PF00928 0.262
TRG_ENDOCYTIC_2 1380 1383 PF00928 0.344
TRG_ENDOCYTIC_2 1386 1389 PF00928 0.344
TRG_ENDOCYTIC_2 1427 1430 PF00928 0.349
TRG_ENDOCYTIC_2 190 193 PF00928 0.568
TRG_ENDOCYTIC_2 34 37 PF00928 0.797
TRG_ENDOCYTIC_2 954 957 PF00928 0.410
TRG_ER_diArg_1 1164 1166 PF00400 0.526
TRG_ER_diArg_1 1261 1263 PF00400 0.369
TRG_ER_diArg_1 1402 1405 PF00400 0.361
TRG_ER_diArg_1 1416 1418 PF00400 0.305
TRG_ER_diArg_1 1474 1477 PF00400 0.365
TRG_ER_diArg_1 287 289 PF00400 0.734
TRG_ER_diArg_1 532 535 PF00400 0.482
TRG_ER_diArg_1 641 643 PF00400 0.470
TRG_ER_diArg_1 645 648 PF00400 0.443
TRG_ER_diArg_1 779 782 PF00400 0.510
TRG_ER_diArg_1 867 869 PF00400 0.457
TRG_NES_CRM1_1 664 679 PF08389 0.533
TRG_NLS_MonoExtC_3 1324 1330 PF00514 0.380
TRG_NLS_MonoExtN_4 369 376 PF00514 0.569
TRG_Pf-PMV_PEXEL_1 506 510 PF00026 0.546
TRG_Pf-PMV_PEXEL_1 526 530 PF00026 0.274
TRG_Pf-PMV_PEXEL_1 680 684 PF00026 0.485

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3H2 Leptomonas seymouri 80% 83%
A0A1X0NNK4 Trypanosomatidae 55% 90%
A0A3S7WT21 Leishmania donovani 100% 100%
A4H7P5 Leishmania braziliensis 91% 100%
C9ZSZ0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 53% 94%
E9APT7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
Q4QFP3 Leishmania major 97% 100%
V5BEB4 Trypanosoma cruzi 58% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS