LeishMANIAdb
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Subtilisin-like serine peptidase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Subtilisin-like serine peptidase
Gene product:
subtilisin-like serine peptidase
Species:
Leishmania infantum
UniProt:
E9AGK0_LEIIN
TriTrypDb:
LINF_130015300
Length:
424

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

E9AGK0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGK0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 281 285 PF00656 0.369
CLV_C14_Caspase3-7 32 36 PF00656 0.390
CLV_NRD_NRD_1 23 25 PF00675 0.573
CLV_NRD_NRD_1 357 359 PF00675 0.625
CLV_PCSK_KEX2_1 23 25 PF00082 0.573
CLV_PCSK_KEX2_1 27 29 PF00082 0.594
CLV_PCSK_KEX2_1 357 359 PF00082 0.625
CLV_PCSK_PC1ET2_1 27 29 PF00082 0.594
CLV_PCSK_PC7_1 23 29 PF00082 0.581
CLV_PCSK_SKI1_1 189 193 PF00082 0.506
CLV_PCSK_SKI1_1 24 28 PF00082 0.581
DEG_SPOP_SBC_1 98 102 PF00917 0.373
DOC_CYCLIN_RxL_1 186 197 PF00134 0.309
DOC_CYCLIN_yCln2_LP_2 390 396 PF00134 0.327
DOC_MAPK_gen_1 111 119 PF00069 0.343
DOC_PP2B_LxvP_1 144 147 PF13499 0.362
DOC_PP2B_LxvP_1 95 98 PF13499 0.351
DOC_USP7_MATH_1 149 153 PF00917 0.378
DOC_USP7_MATH_1 179 183 PF00917 0.360
DOC_USP7_MATH_1 343 347 PF00917 0.423
DOC_USP7_MATH_1 68 72 PF00917 0.408
DOC_USP7_MATH_1 83 87 PF00917 0.382
DOC_WW_Pin1_4 147 152 PF00397 0.380
DOC_WW_Pin1_4 164 169 PF00397 0.340
DOC_WW_Pin1_4 225 230 PF00397 0.422
DOC_WW_Pin1_4 333 338 PF00397 0.406
LIG_14-3-3_CanoR_1 220 229 PF00244 0.421
LIG_14-3-3_CanoR_1 272 278 PF00244 0.339
LIG_APCC_ABBA_1 117 122 PF00400 0.328
LIG_APCC_ABBAyCdc20_2 116 122 PF00400 0.326
LIG_deltaCOP1_diTrp_1 268 274 PF00928 0.344
LIG_FHA_1 195 201 PF00498 0.327
LIG_FHA_1 82 88 PF00498 0.386
LIG_FHA_2 119 125 PF00498 0.343
LIG_FHA_2 257 263 PF00498 0.398
LIG_FHA_2 279 285 PF00498 0.362
LIG_GBD_Chelix_1 187 195 PF00786 0.503
LIG_GBD_Chelix_1 269 277 PF00786 0.540
LIG_LIR_Gen_1 160 168 PF02991 0.346
LIG_LIR_Gen_1 250 261 PF02991 0.416
LIG_LIR_Gen_1 44 53 PF02991 0.383
LIG_LIR_Nem_3 160 164 PF02991 0.348
LIG_LIR_Nem_3 250 256 PF02991 0.425
LIG_LIR_Nem_3 44 50 PF02991 0.380
LIG_NRBOX 139 145 PF00104 0.350
LIG_SH2_STAP1 347 351 PF00017 0.421
LIG_SH2_STAT5 303 306 PF00017 0.374
LIG_SH3_3 148 154 PF00018 0.376
LIG_SH3_3 231 237 PF00018 0.437
LIG_SH3_3 287 293 PF00018 0.389
LIG_SH3_3 332 338 PF00018 0.406
LIG_SH3_3 361 367 PF00018 0.406
LIG_TRAF2_1 3 6 PF00917 0.379
LIG_TRAF2_1 305 308 PF00917 0.362
MOD_CK1_1 105 111 PF00069 0.473
MOD_CK1_1 178 184 PF00069 0.424
MOD_CK1_1 336 342 PF00069 0.499
MOD_CK1_1 81 87 PF00069 0.468
MOD_CK2_1 230 236 PF00069 0.529
MOD_CK2_1 256 262 PF00069 0.486
MOD_CK2_1 273 279 PF00069 0.397
MOD_CK2_1 369 375 PF00069 0.433
MOD_CMANNOS 271 274 PF00535 0.410
MOD_Cter_Amidation 355 358 PF01082 0.508
MOD_GlcNHglycan 107 110 PF01048 0.474
MOD_GlcNHglycan 126 129 PF01048 0.425
MOD_GlcNHglycan 147 150 PF01048 0.452
MOD_GlcNHglycan 177 180 PF01048 0.449
MOD_GlcNHglycan 205 208 PF01048 0.383
MOD_GlcNHglycan 308 311 PF01048 0.409
MOD_GlcNHglycan 35 39 PF01048 0.470
MOD_GlcNHglycan 354 357 PF01048 0.501
MOD_GlcNHglycan 358 361 PF01048 0.510
MOD_GlcNHglycan 401 404 PF01048 0.199
MOD_GSK3_1 120 127 PF00069 0.403
MOD_GSK3_1 145 152 PF00069 0.443
MOD_GSK3_1 153 160 PF00069 0.427
MOD_GSK3_1 175 182 PF00069 0.442
MOD_GSK3_1 220 227 PF00069 0.508
MOD_GSK3_1 26 33 PF00069 0.460
MOD_GSK3_1 273 280 PF00069 0.394
MOD_GSK3_1 333 340 PF00069 0.492
MOD_GSK3_1 343 350 PF00069 0.511
MOD_GSK3_1 352 359 PF00069 0.503
MOD_GSK3_1 369 376 PF00069 0.429
MOD_GSK3_1 81 88 PF00069 0.464
MOD_GSK3_1 93 100 PF00069 0.405
MOD_N-GLC_1 333 338 PF02516 0.489
MOD_NEK2_1 103 108 PF00069 0.474
MOD_NEK2_1 256 261 PF00069 0.489
MOD_NEK2_1 273 278 PF00069 0.391
MOD_NEK2_1 373 378 PF00069 0.416
MOD_NEK2_1 399 404 PF00069 0.199
MOD_NEK2_2 347 352 PF00069 0.508
MOD_PIKK_1 1 7 PF00454 0.459
MOD_PIKK_1 345 351 PF00454 0.510
MOD_PIKK_1 81 87 PF00454 0.468
MOD_PKA_2 203 209 PF00069 0.368
MOD_PKA_2 221 227 PF00069 0.508
MOD_PKA_2 247 253 PF00069 0.513
MOD_PKA_2 356 362 PF00069 0.507
MOD_PKB_1 218 226 PF00069 0.493
MOD_Plk_1 240 246 PF00069 0.513
MOD_Plk_1 68 74 PF00069 0.493
MOD_Plk_4 230 236 PF00069 0.529
MOD_Plk_4 273 279 PF00069 0.397
MOD_Plk_4 284 290 PF00069 0.469
MOD_Plk_4 373 379 PF00069 0.413
MOD_Plk_4 405 411 PF00069 0.199
MOD_Plk_4 99 105 PF00069 0.458
MOD_ProDKin_1 147 153 PF00069 0.452
MOD_ProDKin_1 164 170 PF00069 0.392
MOD_ProDKin_1 225 231 PF00069 0.515
MOD_ProDKin_1 333 339 PF00069 0.490
MOD_SUMO_rev_2 233 239 PF00179 0.532
TRG_DiLeu_BaEn_1 139 144 PF01217 0.408
TRG_DiLeu_BaLyEn_6 169 174 PF01217 0.415
TRG_ER_diArg_1 23 25 PF00400 0.442
TRG_Pf-PMV_PEXEL_1 172 177 PF00026 0.444

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS