LeishMANIAdb
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Transcription initiation factor TFIID subunit 8

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Transcription initiation factor TFIID subunit 8
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AGJ1_LEIIN
TriTrypDb:
LINF_120017100
Length:
213

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized LINJ.12.0870

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGJ1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGJ1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 201 203 PF00675 0.548
CLV_PCSK_FUR_1 199 203 PF00082 0.546
CLV_PCSK_KEX2_1 199 201 PF00082 0.545
CLV_PCSK_KEX2_1 204 206 PF00082 0.558
CLV_PCSK_PC1ET2_1 204 206 PF00082 0.555
CLV_PCSK_PC7_1 200 206 PF00082 0.538
CLV_PCSK_SKI1_1 174 178 PF00082 0.527
CLV_PCSK_SKI1_1 60 64 PF00082 0.607
CLV_Separin_Metazoa 196 200 PF03568 0.443
DEG_APCC_DBOX_1 59 67 PF00400 0.522
DEG_Nend_UBRbox_2 1 3 PF02207 0.677
DOC_PP1_RVXF_1 92 98 PF00149 0.472
DOC_PP4_FxxP_1 143 146 PF00568 0.514
DOC_USP7_MATH_1 78 82 PF00917 0.552
DOC_USP7_UBL2_3 8 12 PF12436 0.538
LIG_14-3-3_CanoR_1 94 98 PF00244 0.566
LIG_Actin_WH2_2 93 108 PF00022 0.434
LIG_AP2alpha_2 51 53 PF02296 0.553
LIG_EVH1_2 127 131 PF00568 0.483
LIG_FHA_1 127 133 PF00498 0.531
LIG_FHA_1 142 148 PF00498 0.465
LIG_FHA_1 176 182 PF00498 0.601
LIG_Integrin_isoDGR_2 137 139 PF01839 0.431
LIG_Integrin_RGD_1 160 162 PF01839 0.591
LIG_LIR_Apic_2 123 127 PF02991 0.474
LIG_LIR_Gen_1 96 105 PF02991 0.532
LIG_LIR_Nem_3 96 100 PF02991 0.537
LIG_SH2_STAT5 121 124 PF00017 0.528
LIG_SH3_3 129 135 PF00018 0.471
LIG_SH3_3 20 26 PF00018 0.555
LIG_SH3_3 61 67 PF00018 0.532
LIG_SH3_5 117 121 PF00018 0.565
LIG_TRAF2_1 107 110 PF00917 0.540
MOD_CK1_1 170 176 PF00069 0.475
MOD_CK1_1 192 198 PF00069 0.434
MOD_GlcNHglycan 27 30 PF01048 0.627
MOD_GlcNHglycan 80 83 PF01048 0.552
MOD_NEK2_1 189 194 PF00069 0.571
MOD_PKA_1 200 206 PF00069 0.593
MOD_PKA_2 189 195 PF00069 0.618
MOD_PKA_2 200 206 PF00069 0.476
MOD_PKA_2 93 99 PF00069 0.587
MOD_Plk_4 19 25 PF00069 0.529
MOD_SUMO_for_1 6 9 PF00179 0.561
MOD_SUMO_rev_2 43 52 PF00179 0.568
TRG_DiLeu_BaEn_1 164 169 PF01217 0.542
TRG_ER_diArg_1 152 155 PF00400 0.569
TRG_ER_diArg_1 198 201 PF00400 0.600
TRG_Pf-PMV_PEXEL_1 106 110 PF00026 0.495

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1ILD1 Leptomonas seymouri 48% 95%
A0A3Q8ICR8 Leishmania donovani 100% 100%
E9AIN7 Leishmania braziliensis 72% 100%
E9AP29 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 98%
Q4QGG0 Leishmania major 86% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS