Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AGJ0_LEIIN

TriTrypDb:

LINF_120017000

Length:

639

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGJ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGJ0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	634	638	PF00656	0.621
CLV_NRD_NRD_1	1	3	PF00675	0.680
CLV_NRD_NRD_1	10	12	PF00675	0.626
CLV_NRD_NRD_1	118	120	PF00675	0.695
CLV_NRD_NRD_1	138	140	PF00675	0.674
CLV_NRD_NRD_1	190	192	PF00675	0.712
CLV_NRD_NRD_1	44	46	PF00675	0.680
CLV_NRD_NRD_1	609	611	PF00675	0.537
CLV_NRD_NRD_1	617	619	PF00675	0.459
CLV_NRD_NRD_1	87	89	PF00675	0.660
CLV_PCSK_FUR_1	116	120	PF00082	0.693
CLV_PCSK_FUR_1	615	619	PF00082	0.520
CLV_PCSK_KEX2_1	116	118	PF00082	0.686
CLV_PCSK_KEX2_1	138	140	PF00082	0.674
CLV_PCSK_KEX2_1	190	192	PF00082	0.797
CLV_PCSK_KEX2_1	44	46	PF00082	0.680
CLV_PCSK_KEX2_1	609	611	PF00082	0.554
CLV_PCSK_KEX2_1	615	617	PF00082	0.464
CLV_PCSK_KEX2_1	87	89	PF00082	0.660
CLV_PCSK_PC7_1	112	118	PF00082	0.568
CLV_PCSK_SKI1_1	385	389	PF00082	0.529
CLV_PCSK_SKI1_1	488	492	PF00082	0.623
CLV_PCSK_SKI1_1	576	580	PF00082	0.686
CLV_PCSK_SKI1_1	610	614	PF00082	0.507
CLV_PCSK_SKI1_1	82	86	PF00082	0.608
CLV_PCSK_SKI1_1	88	92	PF00082	0.571
DEG_COP1_1	194	204	PF00400	0.574
DEG_COP1_1	347	354	PF00400	0.634
DEG_Nend_UBRbox_1	1	4	PF02207	0.657
DEG_SCF_FBW7_1	445	452	PF00400	0.610
DEG_SCF_FBW7_1	577	583	PF00400	0.686
DOC_CKS1_1	219	224	PF01111	0.655
DOC_CKS1_1	346	351	PF01111	0.656
DOC_CKS1_1	36	41	PF01111	0.666
DOC_CKS1_1	446	451	PF01111	0.678
DOC_CKS1_1	543	548	PF01111	0.541
DOC_CKS1_1	577	582	PF01111	0.690
DOC_CYCLIN_yCln2_LP_2	101	104	PF00134	0.495
DOC_MAPK_DCC_7	198	206	PF00069	0.569
DOC_MAPK_gen_1	87	93	PF00069	0.657
DOC_MAPK_MEF2A_6	198	206	PF00069	0.569
DOC_PP2B_LxvP_1	101	104	PF13499	0.598
DOC_PP2B_LxvP_1	406	409	PF13499	0.587
DOC_PP4_FxxP_1	254	257	PF00568	0.600
DOC_PP4_FxxP_1	368	371	PF00568	0.547
DOC_USP7_MATH_1	104	108	PF00917	0.684
DOC_USP7_MATH_1	162	166	PF00917	0.656
DOC_USP7_MATH_1	173	177	PF00917	0.568
DOC_USP7_MATH_1	31	35	PF00917	0.633
DOC_USP7_MATH_1	311	315	PF00917	0.646
DOC_USP7_MATH_1	371	375	PF00917	0.633
DOC_USP7_MATH_1	465	469	PF00917	0.565
DOC_USP7_MATH_1	559	563	PF00917	0.627
DOC_USP7_MATH_1	580	584	PF00917	0.662
DOC_USP7_MATH_1	587	591	PF00917	0.611
DOC_USP7_MATH_1	63	67	PF00917	0.526
DOC_WW_Pin1_4	13	18	PF00397	0.705
DOC_WW_Pin1_4	169	174	PF00397	0.616
DOC_WW_Pin1_4	204	209	PF00397	0.618
DOC_WW_Pin1_4	215	220	PF00397	0.508
DOC_WW_Pin1_4	332	337	PF00397	0.683
DOC_WW_Pin1_4	345	350	PF00397	0.607
DOC_WW_Pin1_4	35	40	PF00397	0.665
DOC_WW_Pin1_4	354	359	PF00397	0.608
DOC_WW_Pin1_4	396	401	PF00397	0.647
DOC_WW_Pin1_4	434	439	PF00397	0.603
DOC_WW_Pin1_4	445	450	PF00397	0.641
DOC_WW_Pin1_4	460	465	PF00397	0.552
DOC_WW_Pin1_4	53	58	PF00397	0.511
DOC_WW_Pin1_4	542	547	PF00397	0.653
DOC_WW_Pin1_4	557	562	PF00397	0.539
DOC_WW_Pin1_4	576	581	PF00397	0.519
DOC_WW_Pin1_4	595	600	PF00397	0.468
LIG_14-3-3_CanoR_1	247	257	PF00244	0.594
LIG_14-3-3_CanoR_1	345	349	PF00244	0.769
LIG_14-3-3_CanoR_1	420	426	PF00244	0.647
LIG_14-3-3_CanoR_1	47	53	PF00244	0.640
LIG_14-3-3_CanoR_1	486	491	PF00244	0.563
LIG_14-3-3_CanoR_1	506	513	PF00244	0.540
LIG_14-3-3_CanoR_1	535	539	PF00244	0.617
LIG_14-3-3_CanoR_1	553	558	PF00244	0.508
LIG_14-3-3_CanoR_1	87	93	PF00244	0.657
LIG_BRCT_BRCA1_1	213	217	PF00533	0.556
LIG_CSL_BTD_1	333	336	PF09270	0.616
LIG_CSL_BTD_1	377	380	PF09270	0.654
LIG_DLG_GKlike_1	2	10	PF00625	0.636
LIG_FHA_1	104	110	PF00498	0.626
LIG_FHA_1	201	207	PF00498	0.661
LIG_FHA_1	346	352	PF00498	0.685
LIG_FHA_1	446	452	PF00498	0.654
LIG_FHA_1	63	69	PF00498	0.600
LIG_FHA_1	94	100	PF00498	0.597
LIG_FHA_2	156	162	PF00498	0.632
LIG_FHA_2	275	281	PF00498	0.663
LIG_FHA_2	360	366	PF00498	0.672
LIG_FHA_2	527	533	PF00498	0.567
LIG_LIR_Apic_2	251	257	PF02991	0.621
LIG_LIR_Apic_2	332	337	PF02991	0.603
LIG_LIR_Apic_2	365	371	PF02991	0.555
LIG_LIR_Gen_1	327	338	PF02991	0.572
LIG_LIR_Nem_3	178	183	PF02991	0.640
LIG_LIR_Nem_3	327	333	PF02991	0.553
LIG_LYPXL_yS_3	360	363	PF13949	0.653
LIG_PDZ_Class_3	634	639	PF00595	0.628
LIG_Pex14_2	330	334	PF04695	0.592
LIG_SH2_CRK	180	184	PF00017	0.583
LIG_SH2_STAT5	567	570	PF00017	0.572
LIG_SH3_1	574	580	PF00018	0.641
LIG_SH3_2	39	44	PF14604	0.668
LIG_SH3_3	14	20	PF00018	0.605
LIG_SH3_3	202	208	PF00018	0.624
LIG_SH3_3	216	222	PF00018	0.491
LIG_SH3_3	228	234	PF00018	0.684
LIG_SH3_3	333	339	PF00018	0.724
LIG_SH3_3	346	352	PF00018	0.608
LIG_SH3_3	355	361	PF00018	0.589
LIG_SH3_3	36	42	PF00018	0.668
LIG_SH3_3	54	60	PF00018	0.501
LIG_SH3_3	540	546	PF00018	0.544
LIG_SH3_3	574	580	PF00018	0.641
LIG_SH3_4	3	10	PF00018	0.622
LIG_SH3_4	82	89	PF00018	0.611
LIG_SUMO_SIM_anti_2	96	103	PF11976	0.515
LIG_SUMO_SIM_par_1	202	207	PF11976	0.616
LIG_TRAF2_1	225	228	PF00917	0.660
MOD_CDC14_SPxK_1	560	563	PF00782	0.626
MOD_CDK_SPK_2	561	566	PF00069	0.582
MOD_CDK_SPxK_1	557	563	PF00069	0.661
MOD_CK1_1	165	171	PF00069	0.677
MOD_CK1_1	172	178	PF00069	0.618
MOD_CK1_1	207	213	PF00069	0.617
MOD_CK1_1	218	224	PF00069	0.516
MOD_CK1_1	266	272	PF00069	0.674
MOD_CK1_1	293	299	PF00069	0.649
MOD_CK1_1	326	332	PF00069	0.619
MOD_CK1_1	347	353	PF00069	0.647
MOD_CK1_1	398	404	PF00069	0.653
MOD_CK1_1	428	434	PF00069	0.656
MOD_CK1_1	48	54	PF00069	0.666
MOD_CK1_1	508	514	PF00069	0.656
MOD_CK1_1	547	553	PF00069	0.610
MOD_CK1_1	569	575	PF00069	0.688
MOD_CK1_1	58	64	PF00069	0.585
MOD_CK1_1	590	596	PF00069	0.638
MOD_CK2_1	108	114	PF00069	0.714
MOD_CK2_1	155	161	PF00069	0.631
MOD_CK2_1	173	179	PF00069	0.504
MOD_CK2_1	267	273	PF00069	0.747
MOD_CK2_1	274	280	PF00069	0.671
MOD_CK2_1	391	397	PF00069	0.598
MOD_CK2_1	48	54	PF00069	0.595
MOD_CK2_1	526	532	PF00069	0.568
MOD_DYRK1A_RPxSP_1	576	580	PF00069	0.620
MOD_GlcNHglycan	130	133	PF01048	0.691
MOD_GlcNHglycan	144	147	PF01048	0.641
MOD_GlcNHglycan	150	153	PF01048	0.639
MOD_GlcNHglycan	174	178	PF01048	0.542
MOD_GlcNHglycan	197	201	PF01048	0.673
MOD_GlcNHglycan	213	216	PF01048	0.544
MOD_GlcNHglycan	244	247	PF01048	0.687
MOD_GlcNHglycan	298	301	PF01048	0.698
MOD_GlcNHglycan	311	314	PF01048	0.605
MOD_GlcNHglycan	320	323	PF01048	0.602
MOD_GlcNHglycan	467	470	PF01048	0.670
MOD_GlcNHglycan	493	496	PF01048	0.638
MOD_GlcNHglycan	507	510	PF01048	0.577
MOD_GlcNHglycan	538	541	PF01048	0.638
MOD_GlcNHglycan	549	552	PF01048	0.539
MOD_GlcNHglycan	582	585	PF01048	0.650
MOD_GlcNHglycan	592	595	PF01048	0.604
MOD_GlcNHglycan	603	606	PF01048	0.460
MOD_GlcNHglycan	96	99	PF01048	0.632
MOD_GSK3_1	104	111	PF00069	0.588
MOD_GSK3_1	165	172	PF00069	0.691
MOD_GSK3_1	196	203	PF00069	0.788
MOD_GSK3_1	207	214	PF00069	0.606
MOD_GSK3_1	242	249	PF00069	0.611
MOD_GSK3_1	252	259	PF00069	0.599
MOD_GSK3_1	260	267	PF00069	0.544
MOD_GSK3_1	290	297	PF00069	0.652
MOD_GSK3_1	31	38	PF00069	0.640
MOD_GSK3_1	311	318	PF00069	0.700
MOD_GSK3_1	325	332	PF00069	0.582
MOD_GSK3_1	350	357	PF00069	0.673
MOD_GSK3_1	359	366	PF00069	0.628
MOD_GSK3_1	391	398	PF00069	0.601
MOD_GSK3_1	430	437	PF00069	0.590
MOD_GSK3_1	445	452	PF00069	0.562
MOD_GSK3_1	459	466	PF00069	0.545
MOD_GSK3_1	48	55	PF00069	0.571
MOD_GSK3_1	486	493	PF00069	0.623
MOD_GSK3_1	507	514	PF00069	0.627
MOD_GSK3_1	515	522	PF00069	0.564
MOD_GSK3_1	534	541	PF00069	0.551
MOD_GSK3_1	553	560	PF00069	0.519
MOD_GSK3_1	576	583	PF00069	0.606
MOD_GSK3_1	58	65	PF00069	0.584
MOD_GSK3_1	595	602	PF00069	0.458
MOD_GSK3_1	7	14	PF00069	0.656
MOD_GSK3_1	89	96	PF00069	0.607
MOD_N-GLC_1	260	265	PF02516	0.555
MOD_N-GLC_1	434	439	PF02516	0.574
MOD_N-GLC_1	569	574	PF02516	0.690
MOD_N-GLC_1	630	635	PF02516	0.574
MOD_NEK2_1	196	201	PF00069	0.669
MOD_NEK2_1	260	265	PF00069	0.774
MOD_NEK2_1	290	295	PF00069	0.689
MOD_NEK2_1	363	368	PF00069	0.623
MOD_NEK2_1	52	57	PF00069	0.572
MOD_PIKK_1	162	168	PF00454	0.616
MOD_PIKK_1	425	431	PF00454	0.704
MOD_PK_1	486	492	PF00069	0.561
MOD_PKA_1	11	17	PF00069	0.597
MOD_PKA_1	2	8	PF00069	0.658
MOD_PKA_2	142	148	PF00069	0.664
MOD_PKA_2	246	252	PF00069	0.562
MOD_PKA_2	293	299	PF00069	0.662
MOD_PKA_2	318	324	PF00069	0.670
MOD_PKA_2	344	350	PF00069	0.791
MOD_PKA_2	419	425	PF00069	0.670
MOD_PKA_2	48	54	PF00069	0.595
MOD_PKA_2	505	511	PF00069	0.677
MOD_PKA_2	519	525	PF00069	0.556
MOD_PKA_2	534	540	PF00069	0.512
MOD_PKA_2	86	92	PF00069	0.677
MOD_PKB_1	45	53	PF00069	0.690
MOD_Plk_1	196	202	PF00069	0.581
MOD_Plk_1	630	636	PF00069	0.581
MOD_Plk_4	200	206	PF00069	0.660
MOD_Plk_4	329	335	PF00069	0.666
MOD_Plk_4	359	365	PF00069	0.679
MOD_Plk_4	48	54	PF00069	0.573
MOD_Plk_4	519	525	PF00069	0.642
MOD_ProDKin_1	13	19	PF00069	0.703
MOD_ProDKin_1	169	175	PF00069	0.614
MOD_ProDKin_1	204	210	PF00069	0.618
MOD_ProDKin_1	215	221	PF00069	0.509
MOD_ProDKin_1	332	338	PF00069	0.684
MOD_ProDKin_1	345	351	PF00069	0.608
MOD_ProDKin_1	35	41	PF00069	0.665
MOD_ProDKin_1	354	360	PF00069	0.609
MOD_ProDKin_1	396	402	PF00069	0.650
MOD_ProDKin_1	434	440	PF00069	0.606
MOD_ProDKin_1	445	451	PF00069	0.642
MOD_ProDKin_1	460	466	PF00069	0.553
MOD_ProDKin_1	53	59	PF00069	0.507
MOD_ProDKin_1	542	548	PF00069	0.651
MOD_ProDKin_1	557	563	PF00069	0.541
MOD_ProDKin_1	576	582	PF00069	0.513
MOD_ProDKin_1	595	601	PF00069	0.462
TRG_DiLeu_BaLyEn_6	286	291	PF01217	0.595
TRG_ENDOCYTIC_2	180	183	PF00928	0.583
TRG_ENDOCYTIC_2	360	363	PF00928	0.653
TRG_ER_diArg_1	116	119	PF00400	0.690
TRG_ER_diArg_1	137	139	PF00400	0.684
TRG_ER_diArg_1	189	191	PF00400	0.795
TRG_ER_diArg_1	44	47	PF00400	0.684
TRG_ER_diArg_1	574	577	PF00400	0.661
TRG_ER_diArg_1	615	618	PF00400	0.521
TRG_Pf-PMV_PEXEL_1	385	389	PF00026	0.551
TRG_Pf-PMV_PEXEL_1	610	614	PF00026	0.507

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WSA2	Leishmania donovani	98%	100%
E9AIN8	Leishmania braziliensis	50%	97%
E9AP28	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
Q4QGG1	Leishmania major	84%	100%