SNARE associated Golgi protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SNARE associated Golgi protein - putative

Species:

Leishmania infantum

UniProt:

E9AGI5_LEIIN

TriTrypDb:

LINF_120016500

Length:

293

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	12
GO:0110165	cellular anatomical entity	1	12
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

E9AGI5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGI5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	143	147	PF00656	0.468
CLV_C14_Caspase3-7	263	267	PF00656	0.654
CLV_MEL_PAP_1	215	221	PF00089	0.436
CLV_NRD_NRD_1	263	265	PF00675	0.434
CLV_PCSK_KEX2_1	232	234	PF00082	0.664
CLV_PCSK_PC1ET2_1	232	234	PF00082	0.664
CLV_PCSK_SKI1_1	153	157	PF00082	0.250
CLV_PCSK_SKI1_1	16	20	PF00082	0.514
CLV_PCSK_SKI1_1	233	237	PF00082	0.521
DEG_APCC_DBOX_1	15	23	PF00400	0.353
DEG_SCF_FBW7_1	234	240	PF00400	0.386
DOC_CKS1_1	234	239	PF01111	0.404
DOC_MAPK_gen_1	13	23	PF00069	0.330
DOC_MAPK_MEF2A_6	16	25	PF00069	0.248
DOC_MAPK_MEF2A_6	166	175	PF00069	0.462
DOC_PP2B_LxvP_1	194	197	PF13499	0.309
DOC_PP4_FxxP_1	94	97	PF00568	0.328
DOC_USP7_UBL2_3	153	157	PF12436	0.409
DOC_USP7_UBL2_3	67	71	PF12436	0.500
DOC_WW_Pin1_4	176	181	PF00397	0.279
DOC_WW_Pin1_4	188	193	PF00397	0.225
DOC_WW_Pin1_4	233	238	PF00397	0.290
LIG_14-3-3_CanoR_1	159	169	PF00244	0.514
LIG_Actin_WH2_2	41	59	PF00022	0.516
LIG_BIR_II_1	1	5	PF00653	0.341
LIG_FHA_1	137	143	PF00498	0.521
LIG_FHA_1	177	183	PF00498	0.268
LIG_FHA_1	2	8	PF00498	0.425
LIG_FHA_1	238	244	PF00498	0.350
LIG_FHA_1	36	42	PF00498	0.304
LIG_FHA_1	91	97	PF00498	0.324
LIG_FHA_2	234	240	PF00498	0.328
LIG_LIR_Apic_2	93	97	PF02991	0.328
LIG_LIR_Gen_1	168	178	PF02991	0.449
LIG_LIR_Gen_1	213	222	PF02991	0.236
LIG_LIR_Gen_1	236	245	PF02991	0.280
LIG_LIR_Gen_1	36	45	PF02991	0.359
LIG_LIR_Gen_1	85	96	PF02991	0.269
LIG_LIR_Nem_3	168	173	PF02991	0.449
LIG_LIR_Nem_3	213	217	PF02991	0.239
LIG_LIR_Nem_3	236	241	PF02991	0.290
LIG_LIR_Nem_3	27	33	PF02991	0.375
LIG_LIR_Nem_3	275	280	PF02991	0.674
LIG_LIR_Nem_3	36	42	PF02991	0.378
LIG_LIR_Nem_3	85	91	PF02991	0.277
LIG_NRBOX	28	34	PF00104	0.417
LIG_PCNA_PIPBox_1	125	134	PF02747	0.243
LIG_Pex14_1	78	82	PF04695	0.407
LIG_Pex14_2	26	30	PF04695	0.283
LIG_SH2_STAT5	118	121	PF00017	0.290
LIG_SH2_STAT5	172	175	PF00017	0.268
LIG_SH2_STAT5	214	217	PF00017	0.238
LIG_SH2_STAT5	34	37	PF00017	0.291
LIG_SH2_STAT5	88	91	PF00017	0.282
LIG_SH3_1	177	183	PF00018	0.268
LIG_SH3_3	177	183	PF00018	0.268
LIG_SH3_3	18	24	PF00018	0.213
LIG_SH3_3	284	290	PF00018	0.678
LIG_SH3_3	8	14	PF00018	0.381
LIG_SUMO_SIM_anti_2	246	252	PF11976	0.361
LIG_SUMO_SIM_par_1	239	246	PF11976	0.408
LIG_WRC_WIRS_1	198	203	PF05994	0.278
LIG_WRC_WIRS_1	91	96	PF05994	0.328
MOD_CK1_1	160	166	PF00069	0.493
MOD_CK1_1	278	284	PF00069	0.674
MOD_CK1_1	40	46	PF00069	0.394
MOD_CK1_1	55	61	PF00069	0.477
MOD_CK2_1	137	143	PF00069	0.523
MOD_GlcNHglycan	113	116	PF01048	0.419
MOD_GlcNHglycan	224	227	PF01048	0.576
MOD_GlcNHglycan	268	271	PF01048	0.441
MOD_GlcNHglycan	277	280	PF01048	0.440
MOD_GlcNHglycan	283	286	PF01048	0.323
MOD_GlcNHglycan	57	60	PF01048	0.337
MOD_GSK3_1	117	124	PF00069	0.296
MOD_GSK3_1	153	160	PF00069	0.520
MOD_GSK3_1	218	225	PF00069	0.271
MOD_GSK3_1	233	240	PF00069	0.252
MOD_GSK3_1	33	40	PF00069	0.376
MOD_GSK3_1	51	58	PF00069	0.450
MOD_GSK3_1	83	90	PF00069	0.399
MOD_NEK2_1	1	6	PF00069	0.372
MOD_NEK2_1	121	126	PF00069	0.279
MOD_NEK2_1	131	136	PF00069	0.291
MOD_NEK2_1	222	227	PF00069	0.386
MOD_NEK2_1	243	248	PF00069	0.385
MOD_NEK2_1	260	265	PF00069	0.637
MOD_NEK2_1	33	38	PF00069	0.268
MOD_NEK2_1	82	87	PF00069	0.305
MOD_NEK2_2	37	42	PF00069	0.389
MOD_PIKK_1	157	163	PF00454	0.511
MOD_PKA_2	275	281	PF00069	0.700
MOD_Plk_1	51	57	PF00069	0.534
MOD_Plk_4	117	123	PF00069	0.313
MOD_Plk_4	137	143	PF00069	0.521
MOD_Plk_4	202	208	PF00069	0.223
MOD_Plk_4	210	216	PF00069	0.227
MOD_Plk_4	237	243	PF00069	0.339
MOD_Plk_4	246	252	PF00069	0.362
MOD_Plk_4	83	89	PF00069	0.308
MOD_Plk_4	96	102	PF00069	0.238
MOD_ProDKin_1	176	182	PF00069	0.279
MOD_ProDKin_1	188	194	PF00069	0.225
MOD_ProDKin_1	233	239	PF00069	0.290
MOD_SUMO_rev_2	225	234	PF00179	0.468
TRG_AP2beta_CARGO_1	168	177	PF09066	0.436
TRG_ENDOCYTIC_2	118	121	PF00928	0.304
TRG_ENDOCYTIC_2	172	175	PF00928	0.268
TRG_ENDOCYTIC_2	214	217	PF00928	0.225
TRG_ENDOCYTIC_2	77	80	PF00928	0.501
TRG_ENDOCYTIC_2	88	91	PF00928	0.213
TRG_NLS_MonoExtN_4	255	261	PF00514	0.586

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZM9	Leptomonas seymouri	73%	100%
A0A0S4JD94	Bodo saltans	57%	98%
A0A1X0NMH8	Trypanosomatidae	61%	96%
A0A3Q8I9D7	Leishmania donovani	100%	89%
A0A422NV37	Trypanosoma rangeli	56%	100%
A1A5V7	Danio rerio	30%	100%
A4H703	Leishmania braziliensis	81%	100%
A4II98	Xenopus tropicalis	29%	100%
C9ZI22	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	99%
E9AP23	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
O62126	Caenorhabditis elegans	30%	100%
Q08D99	Bos taurus	31%	100%
Q4QGG6	Leishmania major	94%	100%
Q5BJD5	Homo sapiens	29%	100%
Q5FVN2	Rattus norvegicus	30%	100%
Q5RBZ8	Pongo abelii	29%	100%
Q5U4K5	Xenopus laevis	29%	100%
Q5ZIL6	Gallus gallus	30%	100%
Q6NV38	Danio rerio	31%	100%
Q8K1A5	Mus musculus	30%	100%
Q96HV5	Homo sapiens	30%	100%
Q9D8U2	Mus musculus	30%	100%
Q9VX39	Drosophila melanogaster	30%	92%
V5BJQ3	Trypanosoma cruzi	58%	100%