LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AGI4_LEIIN
TriTrypDb:
LINF_120016200 *
Length:
433

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) yes yes: 2
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 4
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGI4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGI4

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 236 240 PF00656 0.510
CLV_C14_Caspase3-7 247 251 PF00656 0.626
CLV_C14_Caspase3-7 384 388 PF00656 0.649
CLV_NRD_NRD_1 293 295 PF00675 0.575
CLV_NRD_NRD_1 299 301 PF00675 0.582
CLV_NRD_NRD_1 320 322 PF00675 0.612
CLV_NRD_NRD_1 365 367 PF00675 0.676
CLV_NRD_NRD_1 81 83 PF00675 0.706
CLV_PCSK_KEX2_1 121 123 PF00082 0.477
CLV_PCSK_KEX2_1 276 278 PF00082 0.735
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HY24 Leptomonas seymouri 45% 75%
A0A3Q8I9I2 Leishmania donovani 100% 77%
A4H700 Leishmania braziliensis 51% 100%
E9AP20 Leishmania mexicana (strain MHOM/GT/2001/U1103) 75% 100%
Q4QGG9 Leishmania major 84% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS