LeishMANIAdb
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CSD domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CSD domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AGI2_LEIIN
TriTrypDb:
LINF_120016000
Length:
877

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized LINJ.12.0780

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGI2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGI2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 127 131 PF00656 0.758
CLV_C14_Caspase3-7 201 205 PF00656 0.723
CLV_C14_Caspase3-7 502 506 PF00656 0.806
CLV_C14_Caspase3-7 730 734 PF00656 0.631
CLV_C14_Caspase3-7 789 793 PF00656 0.541
CLV_NRD_NRD_1 186 188 PF00675 0.625
CLV_NRD_NRD_1 195 197 PF00675 0.686
CLV_NRD_NRD_1 77 79 PF00675 0.791
CLV_NRD_NRD_1 821 823 PF00675 0.739
CLV_NRD_NRD_1 854 856 PF00675 0.673
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IHU8 Leishmania donovani 99% 100%
A4H6Z8 Leishmania braziliensis 69% 99%
C9ZI14 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
E9AP18 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 99%
Q4QGH1 Leishmania major 86% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS