Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AGH6_LEIIN

TriTrypDb:

LINF_120016300

Length:

590

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGH6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGH6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	391	395	PF00656	0.630
CLV_NRD_NRD_1	101	103	PF00675	0.384
CLV_NRD_NRD_1	15	17	PF00675	0.387
CLV_NRD_NRD_1	25	27	PF00675	0.342
CLV_NRD_NRD_1	332	334	PF00675	0.368
CLV_NRD_NRD_1	5	7	PF00675	0.355
CLV_NRD_NRD_1	511	513	PF00675	0.428
CLV_NRD_NRD_1	535	537	PF00675	0.434
CLV_NRD_NRD_1	543	545	PF00675	0.436
CLV_NRD_NRD_1	551	553	PF00675	0.423
CLV_NRD_NRD_1	561	563	PF00675	0.428
CLV_PCSK_FUR_1	509	513	PF00082	0.428
CLV_PCSK_KEX2_1	101	103	PF00082	0.384
CLV_PCSK_KEX2_1	15	17	PF00082	0.387
CLV_PCSK_KEX2_1	24	26	PF00082	0.353
CLV_PCSK_KEX2_1	332	334	PF00082	0.368
CLV_PCSK_KEX2_1	5	7	PF00082	0.355
CLV_PCSK_KEX2_1	511	513	PF00082	0.428
CLV_PCSK_KEX2_1	535	537	PF00082	0.434
CLV_PCSK_KEX2_1	543	545	PF00082	0.436
CLV_PCSK_KEX2_1	551	553	PF00082	0.423
CLV_PCSK_KEX2_1	561	563	PF00082	0.428
CLV_PCSK_SKI1_1	137	141	PF00082	0.372
CLV_PCSK_SKI1_1	526	530	PF00082	0.430
CLV_PCSK_SKI1_1	551	555	PF00082	0.420
DEG_APCC_DBOX_1	314	322	PF00400	0.529
DEG_SPOP_SBC_1	341	345	PF00917	0.588
DEG_SPOP_SBC_1	441	445	PF00917	0.613
DEG_SPOP_SBC_1	467	471	PF00917	0.597
DOC_CYCLIN_yCln2_LP_2	242	245	PF00134	0.399
DOC_CYCLIN_yCln2_LP_2	287	293	PF00134	0.199
DOC_MAPK_FxFP_2	282	285	PF00069	0.199
DOC_MAPK_gen_1	311	320	PF00069	0.523
DOC_MAPK_gen_1	5	12	PF00069	0.537
DOC_MAPK_MEF2A_6	159	167	PF00069	0.571
DOC_MAPK_MEF2A_6	257	266	PF00069	0.326
DOC_MAPK_MEF2A_6	5	12	PF00069	0.537
DOC_MAPK_MEF2A_6	57	65	PF00069	0.528
DOC_PP1_RVXF_1	7	13	PF00149	0.538
DOC_PP2B_LxvP_1	242	245	PF13499	0.399
DOC_PP4_FxxP_1	266	269	PF00568	0.338
DOC_PP4_FxxP_1	282	285	PF00568	0.199
DOC_PP4_FxxP_1	38	41	PF00568	0.541
DOC_USP7_MATH_1	122	126	PF00917	0.561
DOC_USP7_MATH_1	14	18	PF00917	0.577
DOC_USP7_MATH_1	177	181	PF00917	0.559
DOC_USP7_MATH_1	245	249	PF00917	0.353
DOC_USP7_MATH_1	340	344	PF00917	0.584
DOC_USP7_MATH_1	436	440	PF00917	0.610
DOC_USP7_MATH_1	441	445	PF00917	0.613
DOC_USP7_MATH_1	448	452	PF00917	0.616
DOC_USP7_MATH_1	458	462	PF00917	0.609
DOC_USP7_MATH_1	467	471	PF00917	0.597
DOC_USP7_MATH_1	573	577	PF00917	0.623
DOC_USP7_UBL2_3	217	221	PF12436	0.619
DOC_WW_Pin1_4	105	110	PF00397	0.616
DOC_WW_Pin1_4	145	150	PF00397	0.577
DOC_WW_Pin1_4	204	209	PF00397	0.592
DOC_WW_Pin1_4	249	254	PF00397	0.348
DOC_WW_Pin1_4	370	375	PF00397	0.607
DOC_WW_Pin1_4	383	388	PF00397	0.627
DOC_WW_Pin1_4	432	437	PF00397	0.622
DOC_WW_Pin1_4	585	590	PF00397	0.619
LIG_14-3-3_CanoR_1	159	167	PF00244	0.571
LIG_14-3-3_CanoR_1	182	190	PF00244	0.589
LIG_14-3-3_CanoR_1	257	261	PF00244	0.321
LIG_14-3-3_CanoR_1	520	528	PF00244	0.631
LIG_14-3-3_CanoR_1	536	545	PF00244	0.636
LIG_14-3-3_CanoR_1	551	557	PF00244	0.620
LIG_14-3-3_CanoR_1	9	13	PF00244	0.538
LIG_BIR_II_1	1	5	PF00653	0.562
LIG_BRCT_BRCA1_1	34	38	PF00533	0.522
LIG_BRCT_BRCA1_1	468	472	PF00533	0.599
LIG_FHA_1	257	263	PF00498	0.322
LIG_FHA_1	552	558	PF00498	0.620
LIG_FHA_2	527	533	PF00498	0.629
LIG_IRF3_LxIS_1	287	294	PF10401	0.199
LIG_LIR_Apic_2	35	41	PF02991	0.536
LIG_LIR_Gen_1	130	139	PF02991	0.565
LIG_LIR_Gen_1	259	267	PF02991	0.324
LIG_LIR_Nem_3	130	134	PF02991	0.566
LIG_LIR_Nem_3	259	263	PF02991	0.321
LIG_LIR_Nem_3	305	309	PF02991	0.509
LIG_LYPXL_S_1	283	287	PF13949	0.199
LIG_LYPXL_yS_3	284	287	PF13949	0.199
LIG_NRBOX	167	173	PF00104	0.551
LIG_PCNA_yPIPBox_3	114	128	PF02747	0.576
LIG_Pex14_2	38	42	PF04695	0.540
LIG_SH2_CRK	50	54	PF00017	0.556
LIG_SH2_PTP2	62	65	PF00017	0.536
LIG_SH2_STAT5	62	65	PF00017	0.536
LIG_SH3_2	211	216	PF14604	0.600
LIG_SH3_3	160	166	PF00018	0.570
LIG_SH3_3	205	211	PF00018	0.594
LIG_SH3_3	38	44	PF00018	0.545
LIG_SH3_3	435	441	PF00018	0.612
LIG_SUMO_SIM_anti_2	316	322	PF11976	0.531
LIG_SUMO_SIM_par_1	289	294	PF11976	0.199
LIG_TRAF2_1	388	391	PF00917	0.627
LIG_TRFH_1	265	269	PF08558	0.394
LIG_TRFH_1	335	339	PF08558	0.464
LIG_WRC_WIRS_1	128	133	PF05994	0.431
LIG_WW_3	329	333	PF00397	0.422
LIG_WW_3	517	521	PF00397	0.522
MOD_CDK_SPK_2	585	590	PF00069	0.506
MOD_CDK_SPxxK_3	209	216	PF00069	0.480
MOD_CK1_1	155	161	PF00069	0.452
MOD_CK1_1	17	23	PF00069	0.425
MOD_CK1_1	252	258	PF00069	0.381
MOD_CK1_1	32	38	PF00069	0.374
MOD_CK1_1	343	349	PF00069	0.474
MOD_CK1_1	370	376	PF00069	0.489
MOD_CK1_1	439	445	PF00069	0.495
MOD_CK1_1	447	453	PF00069	0.498
MOD_CK1_1	459	465	PF00069	0.488
MOD_CK1_1	466	472	PF00069	0.477
MOD_CK1_1	476	482	PF00069	0.486
MOD_CK1_1	537	543	PF00069	0.532
MOD_CK2_1	385	391	PF00069	0.517
MOD_CK2_1	526	532	PF00069	0.521
MOD_CMANNOS	296	299	PF00535	0.199
MOD_Cter_Amidation	559	562	PF01082	0.513
MOD_GlcNHglycan	1	4	PF01048	0.428
MOD_GlcNHglycan	173	176	PF01048	0.415
MOD_GlcNHglycan	179	182	PF01048	0.439
MOD_GlcNHglycan	191	194	PF01048	0.466
MOD_GlcNHglycan	397	400	PF01048	0.507
MOD_GlcNHglycan	446	449	PF01048	0.508
MOD_GlcNHglycan	465	468	PF01048	0.478
MOD_GlcNHglycan	473	476	PF01048	0.489
MOD_GlcNHglycan	482	485	PF01048	0.488
MOD_GlcNHglycan	497	500	PF01048	0.519
MOD_GlcNHglycan	536	539	PF01048	0.531
MOD_GlcNHglycan	78	81	PF01048	0.389
MOD_GlcNHglycan	89	92	PF01048	0.419
MOD_GSK3_1	16	23	PF00069	0.429
MOD_GSK3_1	177	184	PF00069	0.438
MOD_GSK3_1	217	224	PF00069	0.481
MOD_GSK3_1	245	252	PF00069	0.415
MOD_GSK3_1	29	36	PF00069	0.364
MOD_GSK3_1	341	348	PF00069	0.469
MOD_GSK3_1	366	373	PF00069	0.489
MOD_GSK3_1	432	439	PF00069	0.505
MOD_GSK3_1	440	447	PF00069	0.500
MOD_GSK3_1	448	455	PF00069	0.493
MOD_GSK3_1	456	463	PF00069	0.489
MOD_GSK3_1	467	474	PF00069	0.481
MOD_GSK3_1	476	483	PF00069	0.485
MOD_LATS_1	550	556	PF00433	0.510
MOD_N-GLC_1	395	400	PF02516	0.511
MOD_NEK2_1	127	132	PF00069	0.428
MOD_NEK2_1	171	176	PF00069	0.412
MOD_NEK2_1	199	204	PF00069	0.449
MOD_NEK2_1	291	296	PF00069	0.199
MOD_NEK2_1	85	90	PF00069	0.427
MOD_PIKK_1	223	229	PF00454	0.408
MOD_PIKK_1	52	58	PF00454	0.400
MOD_PK_1	552	558	PF00069	0.508
MOD_PKA_1	15	21	PF00069	0.442
MOD_PKA_1	217	223	PF00069	0.492
MOD_PKA_1	551	557	PF00069	0.509
MOD_PKA_2	15	21	PF00069	0.442
MOD_PKA_2	158	164	PF00069	0.447
MOD_PKA_2	181	187	PF00069	0.463
MOD_PKA_2	256	262	PF00069	0.371
MOD_PKA_2	314	320	PF00069	0.378
MOD_PKA_2	459	465	PF00069	0.488
MOD_PKA_2	480	486	PF00069	0.492
MOD_PKA_2	534	540	PF00069	0.524
MOD_PKA_2	551	557	PF00069	0.509
MOD_PKA_2	8	14	PF00069	0.394
MOD_Plk_4	127	133	PF00069	0.430
MOD_Plk_4	166	172	PF00069	0.412
MOD_Plk_4	238	244	PF00069	0.199
MOD_Plk_4	256	262	PF00069	0.371
MOD_Plk_4	29	35	PF00069	0.360
MOD_Plk_4	409	415	PF00069	0.484
MOD_Plk_4	452	458	PF00069	0.485
MOD_Plk_4	468	474	PF00069	0.482
MOD_Plk_4	552	558	PF00069	0.508
MOD_ProDKin_1	105	111	PF00069	0.503
MOD_ProDKin_1	145	151	PF00069	0.447
MOD_ProDKin_1	204	210	PF00069	0.470
MOD_ProDKin_1	249	255	PF00069	0.401
MOD_ProDKin_1	370	376	PF00069	0.489
MOD_ProDKin_1	383	389	PF00069	0.516
MOD_ProDKin_1	432	438	PF00069	0.508
MOD_SUMO_rev_2	405	413	PF00179	0.486
TRG_DiLeu_BaEn_1	316	321	PF01217	0.383
TRG_DiLeu_BaLyEn_6	135	140	PF01217	0.433
TRG_DiLeu_BaLyEn_6	163	168	PF01217	0.427
TRG_DiLeu_BaLyEn_6	333	338	PF01217	0.455
TRG_ENDOCYTIC_2	284	287	PF00928	0.199
TRG_ENDOCYTIC_2	50	53	PF00928	0.422
TRG_ENDOCYTIC_2	62	65	PF00928	0.390
TRG_ER_diArg_1	100	102	PF00400	0.447
TRG_ER_diArg_1	24	26	PF00400	0.415
TRG_ER_diArg_1	331	333	PF00400	0.435
TRG_ER_diArg_1	4	6	PF00400	0.421
TRG_ER_diArg_1	509	512	PF00400	0.523
TRG_ER_diArg_1	543	545	PF00400	0.531
TRG_ER_diArg_1	551	553	PF00400	0.512
TRG_ER_diArg_1	561	563	PF00400	0.520
TRG_ER_FFAT_2	466	477	PF00635	0.482
TRG_NLS_MonoExtN_4	213	220	PF00514	0.497
TRG_Pf-PMV_PEXEL_1	25	29	PF00026	0.397