Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AGH4_LEIIN

TriTrypDb:

LINF_120016300

Length:

903

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGH4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGH4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	280	284	PF00656	0.651
CLV_C14_Caspase3-7	477	481	PF00656	0.698
CLV_C14_Caspase3-7	573	577	PF00656	0.584
CLV_C14_Caspase3-7	609	613	PF00656	0.639
CLV_C14_Caspase3-7	756	760	PF00656	0.677
CLV_NRD_NRD_1	100	102	PF00675	0.613
CLV_NRD_NRD_1	110	112	PF00675	0.767
CLV_NRD_NRD_1	236	238	PF00675	0.723
CLV_NRD_NRD_1	307	309	PF00675	0.681
CLV_NRD_NRD_1	425	427	PF00675	0.728
CLV_NRD_NRD_1	430	432	PF00675	0.682
CLV_NRD_NRD_1	469	471	PF00675	0.709
CLV_NRD_NRD_1	497	499	PF00675	0.755
CLV_NRD_NRD_1	581	583	PF00675	0.624
CLV_NRD_NRD_1	60	62	PF00675	0.777
CLV_NRD_NRD_1	643	645	PF00675	0.566
CLV_NRD_NRD_1	736	738	PF00675	0.660
CLV_NRD_NRD_1	775	777	PF00675	0.505
CLV_NRD_NRD_1	84	86	PF00675	0.726
CLV_NRD_NRD_1	92	94	PF00675	0.738
CLV_PCSK_FUR_1	423	427	PF00082	0.728
CLV_PCSK_FUR_1	58	62	PF00082	0.656
CLV_PCSK_KEX2_1	100	102	PF00082	0.613
CLV_PCSK_KEX2_1	110	112	PF00082	0.767
CLV_PCSK_KEX2_1	236	238	PF00082	0.723
CLV_PCSK_KEX2_1	307	309	PF00082	0.681
CLV_PCSK_KEX2_1	423	425	PF00082	0.728
CLV_PCSK_KEX2_1	430	432	PF00082	0.661
CLV_PCSK_KEX2_1	469	471	PF00082	0.709
CLV_PCSK_KEX2_1	497	499	PF00082	0.755
CLV_PCSK_KEX2_1	581	583	PF00082	0.624
CLV_PCSK_KEX2_1	60	62	PF00082	0.770
CLV_PCSK_KEX2_1	736	738	PF00082	0.660
CLV_PCSK_KEX2_1	775	777	PF00082	0.507
CLV_PCSK_KEX2_1	84	86	PF00082	0.726
CLV_PCSK_KEX2_1	92	94	PF00082	0.738
CLV_PCSK_PC7_1	426	432	PF00082	0.730
CLV_PCSK_SKI1_1	100	104	PF00082	0.528
CLV_PCSK_SKI1_1	262	266	PF00082	0.654
CLV_PCSK_SKI1_1	408	412	PF00082	0.707
CLV_PCSK_SKI1_1	469	473	PF00082	0.770
CLV_PCSK_SKI1_1	555	559	PF00082	0.698
CLV_PCSK_SKI1_1	75	79	PF00082	0.660
CLV_PCSK_SKI1_1	826	830	PF00082	0.636
CLV_PCSK_SKI1_1	891	895	PF00082	0.688
DEG_APCC_DBOX_1	468	476	PF00400	0.708
DEG_APCC_DBOX_1	554	562	PF00400	0.587
DEG_APCC_DBOX_1	777	785	PF00400	0.563
DEG_Kelch_Keap1_1	876	881	PF01344	0.567
DEG_SCF_TRCP1_1	878	884	PF00400	0.552
DEG_SIAH_1	185	193	PF03145	0.568
DEG_SPOP_SBC_1	16	20	PF00917	0.684
DEG_SPOP_SBC_1	438	442	PF00917	0.712
DEG_SPOP_SBC_1	545	549	PF00917	0.705
DEG_SPOP_SBC_1	711	715	PF00917	0.625
DOC_CYCLIN_yCln2_LP_2	672	678	PF00134	0.646
DOC_MAPK_gen_1	469	475	PF00069	0.711
DOC_PP2B_LxvP_1	230	233	PF13499	0.644
DOC_PP2B_LxvP_1	672	675	PF13499	0.666
DOC_PP4_FxxP_1	678	681	PF00568	0.673
DOC_USP7_MATH_1	122	126	PF00917	0.717
DOC_USP7_MATH_1	16	20	PF00917	0.524
DOC_USP7_MATH_1	217	221	PF00917	0.613
DOC_USP7_MATH_1	235	239	PF00917	0.673
DOC_USP7_MATH_1	258	262	PF00917	0.738
DOC_USP7_MATH_1	290	294	PF00917	0.707
DOC_USP7_MATH_1	348	352	PF00917	0.687
DOC_USP7_MATH_1	371	375	PF00917	0.690
DOC_USP7_MATH_1	438	442	PF00917	0.805
DOC_USP7_MATH_1	483	487	PF00917	0.579
DOC_USP7_MATH_1	531	535	PF00917	0.662
DOC_USP7_MATH_1	543	547	PF00917	0.585
DOC_USP7_MATH_1	7	11	PF00917	0.593
DOC_USP7_MATH_1	750	754	PF00917	0.642
DOC_USP7_MATH_1	757	761	PF00917	0.606
DOC_USP7_MATH_1	808	812	PF00917	0.697
DOC_USP7_UBL2_3	262	266	PF12436	0.581
DOC_USP7_UBL2_3	645	649	PF12436	0.583
DOC_WW_Pin1_4	134	139	PF00397	0.584
DOC_WW_Pin1_4	173	178	PF00397	0.646
DOC_WW_Pin1_4	197	202	PF00397	0.668
DOC_WW_Pin1_4	210	215	PF00397	0.579
DOC_WW_Pin1_4	223	228	PF00397	0.572
DOC_WW_Pin1_4	333	338	PF00397	0.666
DOC_WW_Pin1_4	408	413	PF00397	0.708
DOC_WW_Pin1_4	425	430	PF00397	0.542
DOC_WW_Pin1_4	434	439	PF00397	0.617
DOC_WW_Pin1_4	488	493	PF00397	0.691
DOC_WW_Pin1_4	504	509	PF00397	0.549
DOC_WW_Pin1_4	550	555	PF00397	0.695
DOC_WW_Pin1_4	690	695	PF00397	0.594
DOC_WW_Pin1_4	834	839	PF00397	0.786
DOC_WW_Pin1_4	841	846	PF00397	0.686
LIG_14-3-3_CanoR_1	100	106	PF00244	0.690
LIG_14-3-3_CanoR_1	147	157	PF00244	0.554
LIG_14-3-3_CanoR_1	208	216	PF00244	0.601
LIG_14-3-3_CanoR_1	236	244	PF00244	0.783
LIG_14-3-3_CanoR_1	259	265	PF00244	0.649
LIG_14-3-3_CanoR_1	307	313	PF00244	0.667
LIG_14-3-3_CanoR_1	349	353	PF00244	0.671
LIG_14-3-3_CanoR_1	423	429	PF00244	0.728
LIG_14-3-3_CanoR_1	470	476	PF00244	0.707
LIG_14-3-3_CanoR_1	584	593	PF00244	0.602
LIG_14-3-3_CanoR_1	619	628	PF00244	0.647
LIG_14-3-3_CanoR_1	69	77	PF00244	0.714
LIG_14-3-3_CanoR_1	741	747	PF00244	0.614
LIG_14-3-3_CanoR_1	826	834	PF00244	0.636
LIG_14-3-3_CanoR_1	85	94	PF00244	0.641
LIG_14-3-3_CterR_2	898	903	PF00244	0.619
LIG_BRCT_BRCA1_1	17	21	PF00533	0.623
LIG_BRCT_BRCA1_1	308	312	PF00533	0.677
LIG_BRCT_BRCA1_1	744	748	PF00533	0.591
LIG_DLG_GKlike_1	308	316	PF00625	0.679
LIG_EVH1_2	674	678	PF00568	0.644
LIG_FHA_1	101	107	PF00498	0.777
LIG_FHA_1	138	144	PF00498	0.634
LIG_FHA_1	162	168	PF00498	0.646
LIG_FHA_1	204	210	PF00498	0.703
LIG_FHA_1	252	258	PF00498	0.624
LIG_FHA_1	296	302	PF00498	0.594
LIG_FHA_1	311	317	PF00498	0.625
LIG_FHA_1	359	365	PF00498	0.671
LIG_FHA_1	438	444	PF00498	0.703
LIG_FHA_1	483	489	PF00498	0.645
LIG_FHA_1	606	612	PF00498	0.595
LIG_FHA_1	634	640	PF00498	0.665
LIG_FHA_1	675	681	PF00498	0.697
LIG_FHA_1	712	718	PF00498	0.682
LIG_FHA_1	741	747	PF00498	0.693
LIG_FHA_1	749	755	PF00498	0.670
LIG_FHA_1	827	833	PF00498	0.638
LIG_FHA_1	849	855	PF00498	0.590
LIG_FHA_1	882	888	PF00498	0.572
LIG_FHA_2	278	284	PF00498	0.652
LIG_FHA_2	475	481	PF00498	0.707
LIG_FHA_2	482	488	PF00498	0.640
LIG_FHA_2	546	552	PF00498	0.700
LIG_FHA_2	571	577	PF00498	0.598
LIG_FHA_2	585	591	PF00498	0.614
LIG_FHA_2	607	613	PF00498	0.665
LIG_FHA_2	659	665	PF00498	0.592
LIG_FHA_2	742	748	PF00498	0.620
LIG_FHA_2	76	82	PF00498	0.671
LIG_FHA_2	883	889	PF00498	0.525
LIG_LIR_Apic_2	322	327	PF02991	0.655
LIG_LIR_Apic_2	416	422	PF02991	0.719
LIG_LIR_Apic_2	677	681	PF02991	0.671
LIG_PTAP_UEV_1	596	601	PF05743	0.624
LIG_SH2_CRK	419	423	PF00017	0.672
LIG_SH2_CRK	788	792	PF00017	0.482
LIG_SH2_NCK_1	324	328	PF00017	0.657
LIG_SH2_SRC	419	422	PF00017	0.670
LIG_SH2_STAP1	509	513	PF00017	0.659
LIG_SH2_STAP1	788	792	PF00017	0.555
LIG_SH2_STAT5	170	173	PF00017	0.638
LIG_SH2_STAT5	500	503	PF00017	0.641
LIG_SH3_2	232	237	PF14604	0.714
LIG_SH3_2	765	770	PF14604	0.595
LIG_SH3_3	171	177	PF00018	0.677
LIG_SH3_3	226	232	PF00018	0.698
LIG_SH3_3	374	380	PF00018	0.813
LIG_SH3_3	395	401	PF00018	0.649
LIG_SH3_3	432	438	PF00018	0.714
LIG_SH3_3	490	496	PF00018	0.623
LIG_SH3_3	590	596	PF00018	0.720
LIG_SH3_3	636	642	PF00018	0.654
LIG_SH3_3	688	694	PF00018	0.686
LIG_SH3_3	762	768	PF00018	0.787
LIG_SH3_3	835	841	PF00018	0.679
LIG_SH3_3	858	864	PF00018	0.762
LIG_SH3_CIN85_PxpxPR_1	231	236	PF14604	0.656
LIG_SUMO_SIM_par_1	275	281	PF11976	0.568
LIG_SUMO_SIM_par_1	471	477	PF11976	0.749
LIG_TRAF2_1	731	734	PF00917	0.612
LIG_TRAF2_1	753	756	PF00917	0.678
LIG_WW_3	420	424	PF00397	0.720
LIG_WW_3	641	645	PF00397	0.582
LIG_WW_3	66	70	PF00397	0.603
MOD_CDK_SPK_2	134	139	PF00069	0.560
MOD_CDK_SPK_2	425	430	PF00069	0.727
MOD_CDK_SPK_2	550	555	PF00069	0.695
MOD_CDK_SPxK_1	425	431	PF00069	0.730
MOD_CK1_1	137	143	PF00069	0.641
MOD_CK1_1	148	154	PF00069	0.579
MOD_CK1_1	15	21	PF00069	0.542
MOD_CK1_1	210	216	PF00069	0.657
MOD_CK1_1	25	31	PF00069	0.521
MOD_CK1_1	260	266	PF00069	0.797
MOD_CK1_1	270	276	PF00069	0.660
MOD_CK1_1	311	317	PF00069	0.680
MOD_CK1_1	336	342	PF00069	0.587
MOD_CK1_1	363	369	PF00069	0.797
MOD_CK1_1	370	376	PF00069	0.709
MOD_CK1_1	437	443	PF00069	0.761
MOD_CK1_1	446	452	PF00069	0.631
MOD_CK1_1	458	464	PF00069	0.574
MOD_CK1_1	476	482	PF00069	0.539
MOD_CK1_1	504	510	PF00069	0.686
MOD_CK1_1	544	550	PF00069	0.704
MOD_CK1_1	553	559	PF00069	0.603
MOD_CK1_1	598	604	PF00069	0.711
MOD_CK1_1	621	627	PF00069	0.616
MOD_CK1_1	658	664	PF00069	0.677
MOD_CK1_1	683	689	PF00069	0.818
MOD_CK1_1	690	696	PF00069	0.709
MOD_CK1_1	8	14	PF00069	0.580
MOD_CK1_1	844	850	PF00069	0.690
MOD_CK1_1	86	92	PF00069	0.600
MOD_CK1_1	868	874	PF00069	0.729
MOD_CK1_1	876	882	PF00069	0.618
MOD_CK2_1	319	325	PF00069	0.652
MOD_CK2_1	481	487	PF00069	0.659
MOD_CK2_1	545	551	PF00069	0.702
MOD_CK2_1	557	563	PF00069	0.696
MOD_CK2_1	658	664	PF00069	0.640
MOD_CK2_1	694	700	PF00069	0.578
MOD_CK2_1	75	81	PF00069	0.637
MOD_CK2_1	750	756	PF00069	0.654
MOD_Cter_Amidation	108	111	PF01082	0.661
MOD_Cter_Amidation	734	737	PF01082	0.667
MOD_DYRK1A_RPxSP_1	333	337	PF00069	0.701
MOD_DYRK1A_RPxSP_1	408	412	PF00069	0.658
MOD_GlcNHglycan	14	17	PF01048	0.563
MOD_GlcNHglycan	219	222	PF01048	0.686
MOD_GlcNHglycan	22	25	PF01048	0.621
MOD_GlcNHglycan	239	242	PF01048	0.813
MOD_GlcNHglycan	269	272	PF01048	0.727
MOD_GlcNHglycan	31	34	PF01048	0.541
MOD_GlcNHglycan	313	316	PF01048	0.682
MOD_GlcNHglycan	319	322	PF01048	0.632
MOD_GlcNHglycan	329	332	PF01048	0.539
MOD_GlcNHglycan	369	372	PF01048	0.674
MOD_GlcNHglycan	404	407	PF01048	0.629
MOD_GlcNHglycan	408	411	PF01048	0.628
MOD_GlcNHglycan	432	435	PF01048	0.771
MOD_GlcNHglycan	458	461	PF01048	0.705
MOD_GlcNHglycan	46	49	PF01048	0.776
MOD_GlcNHglycan	466	469	PF01048	0.637
MOD_GlcNHglycan	548	551	PF01048	0.698
MOD_GlcNHglycan	597	600	PF01048	0.623
MOD_GlcNHglycan	621	624	PF01048	0.660
MOD_GlcNHglycan	657	660	PF01048	0.775
MOD_GlcNHglycan	800	803	PF01048	0.583
MOD_GlcNHglycan	85	88	PF01048	0.606
MOD_GlcNHglycan	857	860	PF01048	0.745
MOD_GlcNHglycan	867	870	PF01048	0.638
MOD_GlcNHglycan	877	881	PF01048	0.493
MOD_GSK3_1	1	8	PF00069	0.661
MOD_GSK3_1	11	18	PF00069	0.612
MOD_GSK3_1	173	180	PF00069	0.564
MOD_GSK3_1	203	210	PF00069	0.785
MOD_GSK3_1	215	222	PF00069	0.621
MOD_GSK3_1	22	29	PF00069	0.548
MOD_GSK3_1	278	285	PF00069	0.597
MOD_GSK3_1	290	297	PF00069	0.591
MOD_GSK3_1	302	309	PF00069	0.656
MOD_GSK3_1	329	336	PF00069	0.690
MOD_GSK3_1	360	367	PF00069	0.703
MOD_GSK3_1	371	378	PF00069	0.576
MOD_GSK3_1	400	407	PF00069	0.672
MOD_GSK3_1	430	437	PF00069	0.813
MOD_GSK3_1	439	446	PF00069	0.705
MOD_GSK3_1	483	490	PF00069	0.640
MOD_GSK3_1	500	507	PF00069	0.620
MOD_GSK3_1	537	544	PF00069	0.691
MOD_GSK3_1	546	553	PF00069	0.581
MOD_GSK3_1	595	602	PF00069	0.705
MOD_GSK3_1	654	661	PF00069	0.720
MOD_GSK3_1	679	686	PF00069	0.787
MOD_GSK3_1	690	697	PF00069	0.647
MOD_GSK3_1	712	719	PF00069	0.727
MOD_GSK3_1	808	815	PF00069	0.657
MOD_GSK3_1	832	839	PF00069	0.650
MOD_GSK3_1	841	848	PF00069	0.705
MOD_GSK3_1	867	874	PF00069	0.735
MOD_LATS_1	234	240	PF00433	0.718
MOD_LATS_1	358	364	PF00433	0.707
MOD_LATS_1	99	105	PF00433	0.709
MOD_N-GLC_1	413	418	PF02516	0.676
MOD_N-GLC_1	501	506	PF02516	0.564
MOD_N-GLC_1	612	617	PF02516	0.599
MOD_N-GLC_1	655	660	PF02516	0.675
MOD_N-GLC_1	855	860	PF02516	0.729
MOD_NEK2_1	215	220	PF00069	0.679
MOD_NEK2_1	277	282	PF00069	0.656
MOD_NEK2_1	306	311	PF00069	0.678
MOD_NEK2_1	329	334	PF00069	0.658
MOD_NEK2_1	402	407	PF00069	0.711
MOD_NEK2_1	443	448	PF00069	0.699
MOD_NEK2_1	471	476	PF00069	0.661
MOD_NEK2_1	557	562	PF00069	0.695
MOD_NEK2_1	665	670	PF00069	0.615
MOD_NEK2_1	748	753	PF00069	0.594
MOD_NEK2_1	798	803	PF00069	0.584
MOD_NEK2_1	833	838	PF00069	0.656
MOD_NEK2_1	865	870	PF00069	0.701
MOD_NEK2_2	371	376	PF00069	0.632
MOD_NEK2_2	633	638	PF00069	0.565
MOD_NEK2_2	724	729	PF00069	0.647
MOD_PIKK_1	137	143	PF00454	0.653
MOD_PIKK_1	203	209	PF00454	0.640
MOD_PIKK_1	400	406	PF00454	0.671
MOD_PIKK_1	474	480	PF00454	0.707
MOD_PIKK_1	683	689	PF00454	0.671
MOD_PIKK_1	809	815	PF00454	0.578
MOD_PK_1	101	107	PF00069	0.707
MOD_PK_1	360	366	PF00069	0.713
MOD_PKA_1	100	106	PF00069	0.568
MOD_PKA_1	236	242	PF00069	0.715
MOD_PKA_1	424	430	PF00069	0.727
MOD_PKA_2	100	106	PF00069	0.719
MOD_PKA_2	207	213	PF00069	0.667
MOD_PKA_2	235	241	PF00069	0.807
MOD_PKA_2	258	264	PF00069	0.712
MOD_PKA_2	29	35	PF00069	0.586
MOD_PKA_2	306	312	PF00069	0.660
MOD_PKA_2	348	354	PF00069	0.649
MOD_PKA_2	375	381	PF00069	0.782
MOD_PKA_2	424	430	PF00069	0.727
MOD_PKA_2	618	624	PF00069	0.661
MOD_PKA_2	740	746	PF00069	0.665
MOD_PKA_2	8	14	PF00069	0.725
MOD_PKA_2	83	89	PF00069	0.624
MOD_PKB_1	582	590	PF00069	0.602
MOD_Plk_2-3	612	618	PF00069	0.601
MOD_Plk_4	1	7	PF00069	0.814
MOD_Plk_4	101	107	PF00069	0.707
MOD_Plk_4	17	23	PF00069	0.540
MOD_Plk_4	219	225	PF00069	0.633
MOD_Plk_4	260	266	PF00069	0.686
MOD_Plk_4	680	686	PF00069	0.697
MOD_Plk_4	845	851	PF00069	0.575
MOD_ProDKin_1	134	140	PF00069	0.582
MOD_ProDKin_1	173	179	PF00069	0.649
MOD_ProDKin_1	197	203	PF00069	0.668
MOD_ProDKin_1	210	216	PF00069	0.578
MOD_ProDKin_1	223	229	PF00069	0.573
MOD_ProDKin_1	333	339	PF00069	0.666
MOD_ProDKin_1	408	414	PF00069	0.711
MOD_ProDKin_1	425	431	PF00069	0.546
MOD_ProDKin_1	434	440	PF00069	0.617
MOD_ProDKin_1	488	494	PF00069	0.688
MOD_ProDKin_1	504	510	PF00069	0.550
MOD_ProDKin_1	550	556	PF00069	0.694
MOD_ProDKin_1	690	696	PF00069	0.596
MOD_ProDKin_1	834	840	PF00069	0.786
MOD_ProDKin_1	841	847	PF00069	0.688
TRG_DiLeu_BaLyEn_6	467	472	PF01217	0.653
TRG_ENDOCYTIC_2	634	637	PF00928	0.728
TRG_ENDOCYTIC_2	788	791	PF00928	0.557
TRG_ER_diArg_1	100	102	PF00400	0.561
TRG_ER_diArg_1	110	112	PF00400	0.591
TRG_ER_diArg_1	235	237	PF00400	0.723
TRG_ER_diArg_1	306	308	PF00400	0.682
TRG_ER_diArg_1	422	425	PF00400	0.724
TRG_ER_diArg_1	429	431	PF00400	0.663
TRG_ER_diArg_1	469	471	PF00400	0.661
TRG_ER_diArg_1	496	498	PF00400	0.745
TRG_ER_diArg_1	58	61	PF00400	0.705
TRG_ER_diArg_1	581	584	PF00400	0.626
TRG_ER_diArg_1	774	776	PF00400	0.684
TRG_ER_diArg_1	854	857	PF00400	0.574
TRG_ER_diArg_1	92	94	PF00400	0.687
TRG_ER_FFAT_2	15	26	PF00635	0.581
TRG_Pf-PMV_PEXEL_1	775	780	PF00026	0.449

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WS93	Leishmania donovani	99%	89%
A4H701	Leishmania braziliensis	60%	98%
E9AP21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4QGG8	Leishmania major	83%	100%