Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AGD7_LEIIN

TriTrypDb:

LINF_120010100

Length:

317

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGD7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGD7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	39	41	PF00675	0.611
CLV_PCSK_KEX2_1	39	41	PF00082	0.611
DOC_MAPK_gen_1	39	47	PF00069	0.604
DOC_PP2B_LxvP_1	29	32	PF13499	0.695
DOC_PP4_FxxP_1	74	77	PF00568	0.729
DOC_USP7_MATH_1	129	133	PF00917	0.719
DOC_USP7_MATH_1	155	159	PF00917	0.686
DOC_USP7_MATH_1	171	175	PF00917	0.662
DOC_USP7_MATH_1	198	202	PF00917	0.656
DOC_USP7_MATH_1	22	26	PF00917	0.599
DOC_USP7_MATH_1	32	36	PF00917	0.635
DOC_USP7_MATH_1	51	55	PF00917	0.590
DOC_USP7_MATH_2	165	171	PF00917	0.715
DOC_WW_Pin1_4	151	156	PF00397	0.669
DOC_WW_Pin1_4	226	231	PF00397	0.676
LIG_14-3-3_CanoR_1	11	19	PF00244	0.606
LIG_deltaCOP1_diTrp_1	214	223	PF00928	0.622
LIG_FHA_1	136	142	PF00498	0.633
LIG_FHA_1	36	42	PF00498	0.610
LIG_FHA_2	265	271	PF00498	0.680
LIG_LIR_Apic_2	60	65	PF02991	0.684
LIG_LIR_LC3C_4	42	46	PF02991	0.641
LIG_LIR_Nem_3	237	241	PF02991	0.697
LIG_Pex14_1	182	186	PF04695	0.640
LIG_SH2_CRK	62	66	PF00017	0.659
LIG_SH2_STAT5	3	6	PF00017	0.567
LIG_SH2_STAT5	62	65	PF00017	0.643
LIG_SH3_3	42	48	PF00018	0.664
LIG_SH3_3	74	80	PF00018	0.778
LIG_SH3_3	92	98	PF00018	0.733
LIG_SUMO_SIM_anti_2	42	48	PF11976	0.647
LIG_TRAF2_1	230	233	PF00917	0.701
LIG_TRAF2_1	296	299	PF00917	0.640
MOD_CDK_SPK_2	226	231	PF00069	0.676
MOD_CK1_1	127	133	PF00069	0.766
MOD_CK1_1	15	21	PF00069	0.633
MOD_CK1_1	226	232	PF00069	0.678
MOD_CK1_1	35	41	PF00069	0.543
MOD_CK1_1	60	66	PF00069	0.673
MOD_CK1_1	85	91	PF00069	0.733
MOD_CK2_1	15	21	PF00069	0.630
MOD_CK2_1	226	232	PF00069	0.678
MOD_CK2_1	264	270	PF00069	0.595
MOD_CK2_1	292	298	PF00069	0.600
MOD_CK2_1	72	78	PF00069	0.748
MOD_GlcNHglycan	113	116	PF01048	0.666
MOD_GlcNHglycan	131	134	PF01048	0.744
MOD_GlcNHglycan	169	172	PF01048	0.693
MOD_GlcNHglycan	187	190	PF01048	0.658
MOD_GlcNHglycan	204	207	PF01048	0.667
MOD_GlcNHglycan	224	228	PF01048	0.502
MOD_GlcNHglycan	250	253	PF01048	0.763
MOD_GlcNHglycan	294	297	PF01048	0.645
MOD_GlcNHglycan	34	37	PF01048	0.689
MOD_GlcNHglycan	53	56	PF01048	0.589
MOD_GlcNHglycan	85	88	PF01048	0.747
MOD_GSK3_1	107	114	PF00069	0.717
MOD_GSK3_1	11	18	PF00069	0.626
MOD_GSK3_1	124	131	PF00069	0.774
MOD_GSK3_1	145	152	PF00069	0.683
MOD_GSK3_1	163	170	PF00069	0.683
MOD_GSK3_1	187	194	PF00069	0.675
MOD_GSK3_1	198	205	PF00069	0.704
MOD_GSK3_1	20	27	PF00069	0.598
MOD_GSK3_1	219	226	PF00069	0.666
MOD_GSK3_1	244	251	PF00069	0.594
MOD_GSK3_1	31	38	PF00069	0.562
MOD_GSK3_1	53	60	PF00069	0.657
MOD_N-GLC_1	202	207	PF02516	0.602
MOD_N-GLC_1	83	88	PF02516	0.696
MOD_NEK2_1	107	112	PF00069	0.774
MOD_NEK2_1	12	17	PF00069	0.586
MOD_NEK2_1	149	154	PF00069	0.642
MOD_NEK2_1	223	228	PF00069	0.670
MOD_PIKK_1	187	193	PF00454	0.613
MOD_PIKK_1	57	63	PF00454	0.650
MOD_Plk_4	107	113	PF00069	0.713
MOD_Plk_4	157	163	PF00069	0.628
MOD_Plk_4	24	30	PF00069	0.653
MOD_ProDKin_1	151	157	PF00069	0.671
MOD_ProDKin_1	226	232	PF00069	0.678
MOD_SUMO_rev_2	88	98	PF00179	0.694
TRG_DiLeu_BaLyEn_6	68	73	PF01217	0.699
TRG_ER_diArg_1	39	41	PF00400	0.622
TRG_Pf-PMV_PEXEL_1	175	179	PF00026	0.671

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8I979	Leishmania donovani	99%	100%
A4H6W8	Leishmania braziliensis	69%	100%
E9ANX7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QGP3	Leishmania major	92%	100%