LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AGD1_LEIIN
TriTrypDb:
LINF_120009500
Length:
667

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGD1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGD1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 241 245 PF00656 0.656
CLV_C14_Caspase3-7 254 258 PF00656 0.673
CLV_C14_Caspase3-7 415 419 PF00656 0.467
CLV_C14_Caspase3-7 599 603 PF00656 0.621
CLV_NRD_NRD_1 501 503 PF00675 0.576
CLV_NRD_NRD_1 583 585 PF00675 0.756
CLV_NRD_NRD_1 609 611 PF00675 0.571
CLV_PCSK_KEX2_1 501 503 PF00082 0.576
CLV_PCSK_KEX2_1 583 585 PF00082 0.756
CLV_PCSK_KEX2_1 609 611 PF00082 0.571
CLV_PCSK_SKI1_1 174 178 PF00082 0.619
CLV_PCSK_SKI1_1 441 445 PF00082 0.572
CLV_PCSK_SKI1_1 534 538 PF00082 0.664
CLV_PCSK_SKI1_1 598 602 PF00082 0.625
CLV_PCSK_SKI1_1 609 613 PF00082 0.407
DEG_APCC_DBOX_1 433 441 PF00400 0.576
DEG_Nend_Nbox_1 1 3 PF02207 0.528
DEG_SPOP_SBC_1 211 215 PF00917 0.680
DEG_SPOP_SBC_1 82 86 PF00917 0.635
DOC_CKS1_1 180 185 PF01111 0.732
DOC_CKS1_1 442 447 PF01111 0.561
DOC_CKS1_1 537 542 PF01111 0.661
DOC_CYCLIN_RxL_1 531 541 PF00134 0.652
DOC_CYCLIN_yCln2_LP_2 180 186 PF00134 0.732
DOC_CYCLIN_yCln2_LP_2 417 423 PF00134 0.596
DOC_MAPK_gen_1 330 337 PF00069 0.729
DOC_MAPK_gen_1 35 43 PF00069 0.575
DOC_PP2B_LxvP_1 417 420 PF13499 0.528
DOC_PP4_FxxP_1 209 212 PF00568 0.568
DOC_PP4_FxxP_1 467 470 PF00568 0.546
DOC_PP4_FxxP_1 631 634 PF00568 0.545
DOC_USP7_MATH_1 18 22 PF00917 0.619
DOC_USP7_MATH_1 205 209 PF00917 0.670
DOC_USP7_MATH_1 212 216 PF00917 0.646
DOC_USP7_MATH_1 233 237 PF00917 0.718
DOC_USP7_MATH_1 258 262 PF00917 0.713
DOC_USP7_MATH_1 278 282 PF00917 0.665
DOC_USP7_MATH_1 286 290 PF00917 0.682
DOC_USP7_MATH_1 378 382 PF00917 0.754
DOC_USP7_MATH_1 549 553 PF00917 0.721
DOC_USP7_MATH_1 559 563 PF00917 0.638
DOC_USP7_MATH_1 588 592 PF00917 0.658
DOC_USP7_MATH_1 604 608 PF00917 0.489
DOC_USP7_MATH_1 73 77 PF00917 0.712
DOC_USP7_MATH_1 82 86 PF00917 0.619
DOC_USP7_MATH_2 447 453 PF00917 0.465
DOC_WW_Pin1_4 179 184 PF00397 0.731
DOC_WW_Pin1_4 282 287 PF00397 0.796
DOC_WW_Pin1_4 321 326 PF00397 0.752
DOC_WW_Pin1_4 407 412 PF00397 0.674
DOC_WW_Pin1_4 427 432 PF00397 0.372
DOC_WW_Pin1_4 441 446 PF00397 0.417
DOC_WW_Pin1_4 466 471 PF00397 0.547
DOC_WW_Pin1_4 490 495 PF00397 0.513
DOC_WW_Pin1_4 536 541 PF00397 0.694
DOC_WW_Pin1_4 78 83 PF00397 0.720
LIG_14-3-3_CanoR_1 174 179 PF00244 0.628
LIG_14-3-3_CanoR_1 223 233 PF00244 0.706
LIG_14-3-3_CanoR_1 345 354 PF00244 0.795
LIG_14-3-3_CanoR_1 492 498 PF00244 0.551
LIG_14-3-3_CanoR_1 501 511 PF00244 0.442
LIG_14-3-3_CanoR_1 513 519 PF00244 0.456
LIG_14-3-3_CanoR_1 550 558 PF00244 0.545
LIG_14-3-3_CanoR_1 609 615 PF00244 0.532
LIG_14-3-3_CanoR_1 637 645 PF00244 0.549
LIG_BIR_III_4 6 10 PF00653 0.519
LIG_CtBP_PxDLS_1 494 498 PF00389 0.535
LIG_deltaCOP1_diTrp_1 102 109 PF00928 0.613
LIG_deltaCOP1_diTrp_1 418 425 PF00928 0.581
LIG_EVH1_2 408 412 PF00568 0.701
LIG_FHA_1 118 124 PF00498 0.614
LIG_FHA_1 175 181 PF00498 0.643
LIG_FHA_1 198 204 PF00498 0.704
LIG_FHA_1 225 231 PF00498 0.705
LIG_FHA_1 85 91 PF00498 0.746
LIG_FHA_2 252 258 PF00498 0.735
LIG_FHA_2 293 299 PF00498 0.713
LIG_FHA_2 35 41 PF00498 0.734
LIG_FHA_2 473 479 PF00498 0.568
LIG_FHA_2 573 579 PF00498 0.737
LIG_FHA_2 611 617 PF00498 0.518
LIG_IRF3_LxIS_1 180 187 PF10401 0.559
LIG_LIR_Apic_2 207 212 PF02991 0.567
LIG_LIR_Apic_2 465 470 PF02991 0.551
LIG_LIR_Gen_1 106 117 PF02991 0.573
LIG_LIR_Gen_1 449 459 PF02991 0.530
LIG_LIR_Gen_1 484 495 PF02991 0.561
LIG_LIR_Nem_3 102 107 PF02991 0.627
LIG_LIR_Nem_3 108 112 PF02991 0.481
LIG_LIR_Nem_3 418 424 PF02991 0.580
LIG_LIR_Nem_3 449 454 PF02991 0.533
LIG_LIR_Nem_3 456 461 PF02991 0.443
LIG_LIR_Nem_3 478 482 PF02991 0.601
LIG_LIR_Nem_3 484 490 PF02991 0.482
LIG_LIR_Nem_3 578 582 PF02991 0.737
LIG_MYND_1 249 253 PF01753 0.625
LIG_PDZ_Class_2 662 667 PF00595 0.619
LIG_SH2_CRK 13 17 PF00017 0.558
LIG_SH2_CRK 442 446 PF00017 0.564
LIG_SH2_CRK 487 491 PF00017 0.559
LIG_SH2_CRK 579 583 PF00017 0.744
LIG_SH2_NCK_1 511 515 PF00017 0.568
LIG_SH2_STAP1 13 17 PF00017 0.558
LIG_SH2_STAP1 164 168 PF00017 0.587
LIG_SH2_STAP1 511 515 PF00017 0.600
LIG_SH2_STAT5 503 506 PF00017 0.547
LIG_SH2_STAT5 656 659 PF00017 0.530
LIG_SH3_3 246 252 PF00018 0.803
LIG_SH3_3 277 283 PF00018 0.784
LIG_SH3_3 353 359 PF00018 0.605
LIG_SH3_3 405 411 PF00018 0.766
LIG_SH3_3 488 494 PF00018 0.574
LIG_SUMO_SIM_par_1 182 187 PF11976 0.593
LIG_SUMO_SIM_par_1 493 499 PF11976 0.542
LIG_SUMO_SIM_par_1 610 616 PF11976 0.526
LIG_SUMO_SIM_par_1 83 92 PF11976 0.617
LIG_TRAF2_1 21 24 PF00917 0.526
LIG_TYR_ITIM 11 16 PF00017 0.538
LIG_TYR_ITIM 577 582 PF00017 0.565
LIG_WRC_WIRS_1 206 211 PF05994 0.567
LIG_WRC_WIRS_1 661 666 PF05994 0.524
MOD_CDK_SPxxK_3 427 434 PF00069 0.519
MOD_CK1_1 195 201 PF00069 0.620
MOD_CK1_1 385 391 PF00069 0.720
MOD_CK1_1 427 433 PF00069 0.584
MOD_CK1_1 493 499 PF00069 0.495
MOD_CK1_1 564 570 PF00069 0.730
MOD_CK1_1 603 609 PF00069 0.645
MOD_CK1_1 81 87 PF00069 0.667
MOD_CK1_1 89 95 PF00069 0.591
MOD_CK2_1 18 24 PF00069 0.585
MOD_CK2_1 292 298 PF00069 0.716
MOD_CK2_1 407 413 PF00069 0.702
MOD_CK2_1 450 456 PF00069 0.526
MOD_CK2_1 472 478 PF00069 0.570
MOD_CK2_1 493 499 PF00069 0.542
MOD_CK2_1 549 555 PF00069 0.751
MOD_CK2_1 572 578 PF00069 0.736
MOD_CK2_1 610 616 PF00069 0.526
MOD_CK2_1 94 100 PF00069 0.651
MOD_GlcNHglycan 124 127 PF01048 0.608
MOD_GlcNHglycan 186 189 PF01048 0.646
MOD_GlcNHglycan 241 244 PF01048 0.784
MOD_GlcNHglycan 245 248 PF01048 0.743
MOD_GlcNHglycan 288 291 PF01048 0.697
MOD_GlcNHglycan 310 313 PF01048 0.788
MOD_GlcNHglycan 379 383 PF01048 0.772
MOD_GlcNHglycan 384 387 PF01048 0.710
MOD_GlcNHglycan 483 486 PF01048 0.566
MOD_GlcNHglycan 545 548 PF01048 0.734
MOD_GlcNHglycan 551 554 PF01048 0.635
MOD_GlcNHglycan 561 564 PF01048 0.534
MOD_GlcNHglycan 566 569 PF01048 0.658
MOD_GlcNHglycan 57 60 PF01048 0.741
MOD_GlcNHglycan 588 591 PF01048 0.661
MOD_GlcNHglycan 602 605 PF01048 0.472
MOD_GlcNHglycan 64 67 PF01048 0.698
MOD_GSK3_1 233 240 PF00069 0.784
MOD_GSK3_1 278 285 PF00069 0.764
MOD_GSK3_1 292 299 PF00069 0.589
MOD_GSK3_1 30 37 PF00069 0.700
MOD_GSK3_1 308 315 PF00069 0.621
MOD_GSK3_1 358 365 PF00069 0.691
MOD_GSK3_1 378 385 PF00069 0.589
MOD_GSK3_1 397 404 PF00069 0.530
MOD_GSK3_1 486 493 PF00069 0.515
MOD_GSK3_1 549 556 PF00069 0.639
MOD_GSK3_1 566 573 PF00069 0.516
MOD_GSK3_1 588 595 PF00069 0.608
MOD_GSK3_1 596 603 PF00069 0.572
MOD_GSK3_1 78 85 PF00069 0.709
MOD_LATS_1 360 366 PF00433 0.716
MOD_N-GLC_1 238 243 PF02516 0.694
MOD_NEK2_1 184 189 PF00069 0.646
MOD_NEK2_1 197 202 PF00069 0.649
MOD_NEK2_1 237 242 PF00069 0.727
MOD_NEK2_1 308 313 PF00069 0.707
MOD_NEK2_1 389 394 PF00069 0.666
MOD_NEK2_1 424 429 PF00069 0.581
MOD_NEK2_1 548 553 PF00069 0.745
MOD_NEK2_1 554 559 PF00069 0.661
MOD_NEK2_1 566 571 PF00069 0.521
MOD_NEK2_1 600 605 PF00069 0.663
MOD_NEK2_1 617 622 PF00069 0.278
MOD_NEK2_2 233 238 PF00069 0.612
MOD_NEK2_2 514 519 PF00069 0.551
MOD_PIKK_1 403 409 PF00454 0.614
MOD_PK_1 362 368 PF00069 0.714
MOD_PKA_1 44 50 PF00069 0.768
MOD_PKA_2 195 201 PF00069 0.561
MOD_PKA_2 549 555 PF00069 0.589
MOD_Plk_1 107 113 PF00069 0.560
MOD_Plk_1 389 395 PF00069 0.656
MOD_Plk_1 397 403 PF00069 0.686
MOD_Plk_1 449 455 PF00069 0.528
MOD_Plk_1 554 560 PF00069 0.558
MOD_Plk_1 617 623 PF00069 0.508
MOD_Plk_2-3 450 456 PF00069 0.526
MOD_Plk_2-3 596 602 PF00069 0.607
MOD_Plk_4 205 211 PF00069 0.625
MOD_Plk_4 352 358 PF00069 0.609
MOD_Plk_4 397 403 PF00069 0.724
MOD_Plk_4 450 456 PF00069 0.526
MOD_Plk_4 472 478 PF00069 0.570
MOD_Plk_4 486 492 PF00069 0.376
MOD_Plk_4 660 666 PF00069 0.516
MOD_ProDKin_1 179 185 PF00069 0.733
MOD_ProDKin_1 282 288 PF00069 0.792
MOD_ProDKin_1 321 327 PF00069 0.747
MOD_ProDKin_1 407 413 PF00069 0.670
MOD_ProDKin_1 427 433 PF00069 0.364
MOD_ProDKin_1 441 447 PF00069 0.415
MOD_ProDKin_1 466 472 PF00069 0.553
MOD_ProDKin_1 490 496 PF00069 0.506
MOD_ProDKin_1 536 542 PF00069 0.692
MOD_ProDKin_1 78 84 PF00069 0.719
TRG_DiLeu_BaEn_1 456 461 PF01217 0.538
TRG_DiLeu_BaLyEn_6 532 537 PF01217 0.653
TRG_ENDOCYTIC_2 13 16 PF00928 0.549
TRG_ENDOCYTIC_2 487 490 PF00928 0.567
TRG_ENDOCYTIC_2 579 582 PF00928 0.742
TRG_ER_diArg_1 500 502 PF00400 0.564
TRG_ER_diArg_1 532 535 PF00400 0.738
TRG_ER_diArg_1 582 584 PF00400 0.752
TRG_ER_diArg_1 609 611 PF00400 0.574
TRG_Pf-PMV_PEXEL_1 502 506 PF00026 0.556
TRG_Pf-PMV_PEXEL_1 598 602 PF00026 0.610

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WRW8 Leishmania donovani 100% 100%
A4H6V8 Leishmania braziliensis 70% 100%
E9ANX1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%
Q4QGP9 Leishmania major 90% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS