LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
E9AGA6_LEIIN
TriTrypDb:
LINF_120006800
Length:
400

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGA6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGA6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 297 299 PF00675 0.636
CLV_NRD_NRD_1 73 75 PF00675 0.511
CLV_NRD_NRD_1 87 89 PF00675 0.445
CLV_PCSK_KEX2_1 297 299 PF00082 0.636
CLV_PCSK_KEX2_1 72 74 PF00082 0.516
CLV_PCSK_KEX2_1 87 89 PF00082 0.437
CLV_PCSK_SKI1_1 239 243 PF00082 0.506
CLV_PCSK_SKI1_1 300 304 PF00082 0.565
CLV_PCSK_SKI1_1 73 77 PF00082 0.482
DEG_APCC_DBOX_1 299 307 PF00400 0.566
DEG_Nend_UBRbox_4 1 3 PF02207 0.557
DEG_SPOP_SBC_1 157 161 PF00917 0.543
DEG_SPOP_SBC_1 312 316 PF00917 0.635
DEG_SPOP_SBC_1 32 36 PF00917 0.593
DOC_CYCLIN_RxL_1 70 78 PF00134 0.474
DOC_MAPK_RevD_3 283 298 PF00069 0.620
DOC_PP4_FxxP_1 344 347 PF00568 0.410
DOC_USP7_MATH_1 103 107 PF00917 0.580
DOC_USP7_MATH_1 157 161 PF00917 0.604
DOC_USP7_MATH_1 174 178 PF00917 0.608
DOC_USP7_MATH_1 23 27 PF00917 0.642
DOC_USP7_MATH_1 32 36 PF00917 0.562
DOC_WW_Pin1_4 105 110 PF00397 0.506
DOC_WW_Pin1_4 141 146 PF00397 0.481
DOC_WW_Pin1_4 8 13 PF00397 0.618
LIG_14-3-3_CanoR_1 87 96 PF00244 0.599
LIG_BRCT_BRCA1_1 340 344 PF00533 0.375
LIG_eIF4E_1 142 148 PF01652 0.415
LIG_eIF4E_1 70 76 PF01652 0.539
LIG_FHA_1 170 176 PF00498 0.633
LIG_FHA_1 264 270 PF00498 0.615
LIG_FHA_1 332 338 PF00498 0.419
LIG_FHA_2 316 322 PF00498 0.544
LIG_FHA_2 380 386 PF00498 0.493
LIG_FHA_2 9 15 PF00498 0.597
LIG_LIR_Apic_2 341 347 PF02991 0.392
LIG_LIR_Gen_1 206 213 PF02991 0.620
LIG_LIR_Gen_1 48 59 PF02991 0.528
LIG_LIR_Nem_3 206 212 PF02991 0.614
LIG_LIR_Nem_3 48 54 PF02991 0.544
LIG_PDZ_Class_3 395 400 PF00595 0.495
LIG_SH2_STAP1 55 59 PF00017 0.472
LIG_SH2_STAP1 61 65 PF00017 0.438
LIG_SH2_STAT5 142 145 PF00017 0.552
LIG_SH2_STAT5 230 233 PF00017 0.572
LIG_SH2_STAT5 376 379 PF00017 0.475
LIG_SH2_STAT5 388 391 PF00017 0.293
LIG_SH2_STAT5 70 73 PF00017 0.562
LIG_SH3_1 180 186 PF00018 0.649
LIG_SH3_3 178 184 PF00018 0.637
LIG_SH3_3 283 289 PF00018 0.597
LIG_SH3_3 9 15 PF00018 0.560
LIG_SUMO_SIM_anti_2 279 287 PF11976 0.647
LIG_TRAF2_1 277 280 PF00917 0.527
LIG_TRAF2_1 45 48 PF00917 0.570
MOD_CK1_1 158 164 PF00069 0.613
MOD_CK1_1 24 30 PF00069 0.638
MOD_CK1_1 308 314 PF00069 0.641
MOD_CK1_1 31 37 PF00069 0.577
MOD_CK1_1 315 321 PF00069 0.577
MOD_CK1_1 380 386 PF00069 0.481
MOD_CK1_1 49 55 PF00069 0.618
MOD_CK1_1 90 96 PF00069 0.493
MOD_CK2_1 189 195 PF00069 0.572
MOD_CK2_1 315 321 PF00069 0.558
MOD_CK2_1 8 14 PF00069 0.596
MOD_DYRK1A_RPxSP_1 105 109 PF00069 0.508
MOD_GlcNHglycan 115 118 PF01048 0.652
MOD_GlcNHglycan 130 133 PF01048 0.622
MOD_GlcNHglycan 160 163 PF01048 0.640
MOD_GlcNHglycan 172 175 PF01048 0.616
MOD_GlcNHglycan 23 26 PF01048 0.621
MOD_GlcNHglycan 30 33 PF01048 0.679
MOD_GlcNHglycan 315 318 PF01048 0.562
MOD_GlcNHglycan 339 343 PF01048 0.466
MOD_GlcNHglycan 379 382 PF01048 0.461
MOD_GlcNHglycan 62 65 PF01048 0.534
MOD_GlcNHglycan 82 85 PF01048 0.372
MOD_GSK3_1 103 110 PF00069 0.544
MOD_GSK3_1 151 158 PF00069 0.480
MOD_GSK3_1 17 24 PF00069 0.705
MOD_GSK3_1 170 177 PF00069 0.640
MOD_GSK3_1 28 35 PF00069 0.558
MOD_GSK3_1 308 315 PF00069 0.806
MOD_GSK3_1 327 334 PF00069 0.391
MOD_GSK3_1 379 386 PF00069 0.501
MOD_N-GLC_1 226 231 PF02516 0.455
MOD_N-GLC_1 271 276 PF02516 0.680
MOD_N-GLC_1 68 73 PF02516 0.469
MOD_NEK2_1 128 133 PF00069 0.488
MOD_NEK2_1 372 377 PF00069 0.537
MOD_PIKK_1 151 157 PF00454 0.575
MOD_PIKK_1 87 93 PF00454 0.597
MOD_PKA_1 87 93 PF00069 0.628
MOD_PKA_2 327 333 PF00069 0.572
MOD_PKA_2 49 55 PF00069 0.513
MOD_PKA_2 87 93 PF00069 0.628
MOD_Plk_1 119 125 PF00069 0.573
MOD_Plk_1 17 23 PF00069 0.623
MOD_Plk_1 189 195 PF00069 0.618
MOD_Plk_1 226 232 PF00069 0.453
MOD_Plk_1 271 277 PF00069 0.660
MOD_Plk_1 281 287 PF00069 0.503
MOD_Plk_1 319 325 PF00069 0.602
MOD_Plk_1 46 52 PF00069 0.576
MOD_ProDKin_1 105 111 PF00069 0.508
MOD_ProDKin_1 141 147 PF00069 0.482
MOD_ProDKin_1 8 14 PF00069 0.620
TRG_DiLeu_BaLyEn_6 123 128 PF01217 0.507
TRG_DiLeu_BaLyEn_6 71 76 PF01217 0.489
TRG_ENDOCYTIC_2 209 212 PF00928 0.649
TRG_ENDOCYTIC_2 55 58 PF00928 0.448
TRG_ER_diArg_1 296 298 PF00400 0.625
TRG_ER_diArg_1 72 74 PF00400 0.516
TRG_ER_diArg_1 97 100 PF00400 0.500
TRG_Pf-PMV_PEXEL_1 126 130 PF00026 0.502
TRG_Pf-PMV_PEXEL_1 300 304 PF00026 0.560
TRG_Pf-PMV_PEXEL_1 73 77 PF00026 0.560
TRG_Pf-PMV_PEXEL_1 95 99 PF00026 0.491

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PD33 Leptomonas seymouri 29% 85%
A0A3S7WRT8 Leishmania donovani 99% 100%
A4H6T2 Leishmania braziliensis 62% 100%
E9ANU4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 75% 98%
Q4QGS6 Leishmania major 81% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS