LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania infantum
UniProt:
E9AGA1_LEIIN
TriTrypDb:
Length:
71

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AGA1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AGA1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 67 71 PF00082 0.515
DOC_CKS1_1 23 28 PF01111 0.199
DOC_CYCLIN_yCln2_LP_2 23 29 PF00134 0.199
DOC_MAPK_gen_1 37 46 PF00069 0.315
DOC_MAPK_HePTP_8 54 66 PF00069 0.315
DOC_MAPK_MEF2A_6 39 48 PF00069 0.322
DOC_MAPK_MEF2A_6 57 66 PF00069 0.315
DOC_PP2B_LxvP_1 48 51 PF13499 0.296
DOC_PP4_FxxP_1 47 50 PF00568 0.306
DOC_WW_Pin1_4 22 27 PF00397 0.199
LIG_14-3-3_CterR_2 67 71 PF00244 0.315
LIG_FHA_1 23 29 PF00498 0.199
LIG_GBD_Chelix_1 40 48 PF00786 0.322
LIG_Integrin_RGD_1 57 59 PF01839 0.524
LIG_LIR_Apic_2 45 50 PF02991 0.300
LIG_LIR_Gen_1 60 69 PF02991 0.310
LIG_LIR_Nem_3 60 66 PF02991 0.311
LIG_Pex14_2 29 33 PF04695 0.199
LIG_SH2_STAT5 63 66 PF00017 0.307
LIG_WRC_WIRS_1 30 35 PF05994 0.199
MOD_CK2_1 2 8 PF00069 0.503
MOD_GSK3_1 29 36 PF00069 0.199
MOD_NEK2_1 29 34 PF00069 0.199
MOD_NEK2_1 65 70 PF00069 0.305
MOD_NEK2_2 42 47 PF00069 0.286
MOD_NEK2_2 7 12 PF00069 0.495
MOD_PIKK_1 57 63 PF00454 0.319
MOD_Plk_1 7 13 PF00069 0.493
MOD_ProDKin_1 22 28 PF00069 0.199
TRG_ENDOCYTIC_2 63 66 PF00928 0.307
TRG_ER_diArg_1 37 40 PF00400 0.199

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS