Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania infantum

UniProt:

E9AG98_LEIIN

TriTrypDb:

LINF_100010150

Length:

297

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AG98

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AG98

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0004386	helicase activity	2	2
GO:0140640	catalytic activity, acting on a nucleic acid	2	2
GO:0140657	ATP-dependent activity	1	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	224	228	PF00656	0.697
CLV_NRD_NRD_1	122	124	PF00675	0.543
CLV_NRD_NRD_1	231	233	PF00675	0.549
CLV_NRD_NRD_1	265	267	PF00675	0.723
CLV_NRD_NRD_1	46	48	PF00675	0.623
CLV_PCSK_KEX2_1	122	124	PF00082	0.543
CLV_PCSK_KEX2_1	231	233	PF00082	0.549
CLV_PCSK_KEX2_1	265	267	PF00082	0.723
CLV_PCSK_KEX2_1	46	48	PF00082	0.623
DEG_Nend_UBRbox_1	1	4	PF02207	0.563
DOC_CDC14_PxL_1	191	199	PF14671	0.532
DOC_CKS1_1	211	216	PF01111	0.538
DOC_CKS1_1	78	83	PF01111	0.517
DOC_MAPK_gen_1	46	57	PF00069	0.524
DOC_MAPK_MEF2A_6	50	59	PF00069	0.522
DOC_PP2B_LxvP_1	110	113	PF13499	0.536
DOC_PP2B_LxvP_1	201	204	PF13499	0.589
DOC_PP2B_LxvP_1	82	85	PF13499	0.496
DOC_USP7_MATH_1	103	107	PF00917	0.729
DOC_USP7_MATH_1	126	130	PF00917	0.539
DOC_USP7_MATH_1	190	194	PF00917	0.655
DOC_USP7_MATH_1	221	225	PF00917	0.704
DOC_USP7_MATH_1	264	268	PF00917	0.529
DOC_WW_Pin1_4	116	121	PF00397	0.573
DOC_WW_Pin1_4	130	135	PF00397	0.576
DOC_WW_Pin1_4	149	154	PF00397	0.458
DOC_WW_Pin1_4	210	215	PF00397	0.538
DOC_WW_Pin1_4	71	76	PF00397	0.535
DOC_WW_Pin1_4	77	82	PF00397	0.506
LIG_14-3-3_CanoR_1	249	255	PF00244	0.504
LIG_14-3-3_CanoR_1	265	270	PF00244	0.487
LIG_Actin_WH2_2	255	272	PF00022	0.528
LIG_FHA_1	106	112	PF00498	0.723
LIG_FHA_1	236	242	PF00498	0.538
LIG_Integrin_RGD_1	225	227	PF01839	0.524
LIG_LIR_LC3C_4	108	112	PF02991	0.541
LIG_PDZ_Class_2	292	297	PF00595	0.482
LIG_SH3_3	108	114	PF00018	0.538
LIG_SH3_3	184	190	PF00018	0.530
LIG_SH3_3	200	206	PF00018	0.472
LIG_SH3_3	287	293	PF00018	0.489
LIG_SH3_3	60	66	PF00018	0.524
LIG_SH3_3	75	81	PF00018	0.508
MOD_CDK_SPxK_1	116	122	PF00069	0.526
MOD_CDK_SPxxK_3	116	123	PF00069	0.723
MOD_CK1_1	105	111	PF00069	0.717
MOD_CK1_1	29	35	PF00069	0.527
MOD_CK2_1	39	45	PF00069	0.625
MOD_GlcNHglycan	105	108	PF01048	0.581
MOD_GlcNHglycan	192	195	PF01048	0.624
MOD_GlcNHglycan	262	265	PF01048	0.529
MOD_GlcNHglycan	275	278	PF01048	0.486
MOD_GlcNHglycan	28	31	PF01048	0.565
MOD_GlcNHglycan	52	55	PF01048	0.558
MOD_GSK3_1	101	108	PF00069	0.636
MOD_GSK3_1	126	133	PF00069	0.710
MOD_GSK3_1	217	224	PF00069	0.563
MOD_GSK3_1	235	242	PF00069	0.538
MOD_GSK3_1	250	257	PF00069	0.462
MOD_GSK3_1	260	267	PF00069	0.498
MOD_GSK3_1	29	36	PF00069	0.712
MOD_GSK3_1	46	53	PF00069	0.545
MOD_GSK3_1	93	100	PF00069	0.656
MOD_LATS_1	97	103	PF00433	0.571
MOD_N-GLC_1	279	284	PF02516	0.511
MOD_NEK2_1	115	120	PF00069	0.528
MOD_NEK2_1	170	175	PF00069	0.490
MOD_NEK2_1	197	202	PF00069	0.525
MOD_NEK2_1	217	222	PF00069	0.567
MOD_NEK2_1	254	259	PF00069	0.513
MOD_PIKK_1	31	37	PF00454	0.532
MOD_PKA_1	265	271	PF00069	0.537
MOD_PKA_1	46	52	PF00069	0.524
MOD_PKA_2	264	270	PF00069	0.543
MOD_PKA_2	46	52	PF00069	0.582
MOD_Plk_4	106	112	PF00069	0.554
MOD_ProDKin_1	116	122	PF00069	0.574
MOD_ProDKin_1	130	136	PF00069	0.578
MOD_ProDKin_1	149	155	PF00069	0.454
MOD_ProDKin_1	210	216	PF00069	0.537
MOD_ProDKin_1	71	77	PF00069	0.536
TRG_DiLeu_BaLyEn_6	111	116	PF01217	0.535
TRG_ER_diArg_1	209	212	PF00400	0.723
TRG_ER_diArg_1	46	48	PF00400	0.528

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8I7P2	Leishmania donovani	81%	100%
A0A3S5H6F8	Leishmania donovani	81%	100%