Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AG96_LEIIN

TriTrypDb:

LINF_090020600

Length:

350

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AG96

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AG96

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	261	265	PF00656	0.546
CLV_C14_Caspase3-7	305	309	PF00656	0.637
CLV_NRD_NRD_1	111	113	PF00675	0.464
CLV_NRD_NRD_1	286	288	PF00675	0.611
CLV_NRD_NRD_1	334	336	PF00675	0.640
CLV_NRD_NRD_1	81	83	PF00675	0.546
CLV_PCSK_KEX2_1	111	113	PF00082	0.464
CLV_PCSK_KEX2_1	285	287	PF00082	0.608
CLV_PCSK_KEX2_1	334	336	PF00082	0.640
CLV_PCSK_KEX2_1	81	83	PF00082	0.546
DEG_APCC_DBOX_1	93	101	PF00400	0.481
DEG_MDM2_SWIB_1	54	62	PF02201	0.402
DEG_Nend_Nbox_1	1	3	PF02207	0.607
DEG_SPOP_SBC_1	177	181	PF00917	0.648
DOC_CDC14_PxL_1	126	134	PF14671	0.553
DOC_MAPK_gen_1	334	342	PF00069	0.588
DOC_PP2B_LxvP_1	280	283	PF13499	0.616
DOC_USP7_MATH_1	13	17	PF00917	0.661
DOC_USP7_MATH_1	175	179	PF00917	0.641
DOC_USP7_MATH_1	266	270	PF00917	0.724
DOC_USP7_MATH_1	294	298	PF00917	0.620
DOC_USP7_MATH_1	309	313	PF00917	0.602
DOC_WW_Pin1_4	192	197	PF00397	0.667
DOC_WW_Pin1_4	2	7	PF00397	0.595
DOC_WW_Pin1_4	207	212	PF00397	0.490
DOC_WW_Pin1_4	21	26	PF00397	0.551
DOC_WW_Pin1_4	34	39	PF00397	0.492
LIG_BIR_III_4	308	312	PF00653	0.645
LIG_FHA_1	179	185	PF00498	0.614
LIG_FHA_1	255	261	PF00498	0.642
LIG_FHA_1	294	300	PF00498	0.607
LIG_FHA_1	31	37	PF00498	0.575
LIG_FHA_2	126	132	PF00498	0.490
LIG_FHA_2	193	199	PF00498	0.621
LIG_FHA_2	43	49	PF00498	0.410
LIG_LIR_Gen_1	136	146	PF02991	0.637
LIG_LIR_Gen_1	198	208	PF02991	0.541
LIG_LIR_Nem_3	136	141	PF02991	0.627
LIG_LIR_Nem_3	198	203	PF02991	0.536
LIG_LIR_Nem_3	269	274	PF02991	0.664
LIG_MYND_1	272	276	PF01753	0.675
LIG_PDZ_Class_3	345	350	PF00595	0.642
LIG_Pex14_2	54	58	PF04695	0.393
LIG_PTB_Apo_2	48	55	PF02174	0.425
LIG_SH2_STAT5	68	71	PF00017	0.371
LIG_SH3_3	102	108	PF00018	0.494
LIG_SH3_3	16	22	PF00018	0.677
LIG_SUMO_SIM_anti_2	16	24	PF11976	0.677
LIG_SUMO_SIM_anti_2	296	303	PF11976	0.672
LIG_SUMO_SIM_anti_2	339	349	PF11976	0.585
LIG_SUMO_SIM_par_1	16	24	PF11976	0.677
LIG_SUMO_SIM_par_1	296	303	PF11976	0.605
LIG_SUMO_SIM_par_1	339	349	PF11976	0.576
MOD_CDK_SPxK_1	34	40	PF00069	0.541
MOD_CDK_SPxxK_3	207	214	PF00069	0.604
MOD_CK1_1	178	184	PF00069	0.645
MOD_CK1_1	185	191	PF00069	0.702
MOD_CK1_1	218	224	PF00069	0.604
MOD_CK1_1	29	35	PF00069	0.620
MOD_CK2_1	134	140	PF00069	0.625
MOD_CK2_1	192	198	PF00069	0.677
MOD_CK2_1	207	213	PF00069	0.474
MOD_CK2_1	89	95	PF00069	0.620
MOD_CMANNOS	233	236	PF00535	0.410
MOD_Cter_Amidation	283	286	PF01082	0.626
MOD_GlcNHglycan	10	13	PF01048	0.639
MOD_GlcNHglycan	171	174	PF01048	0.563
MOD_GlcNHglycan	222	226	PF01048	0.607
MOD_GlcNHglycan	260	263	PF01048	0.665
MOD_GlcNHglycan	268	271	PF01048	0.558
MOD_GlcNHglycan	296	299	PF01048	0.666
MOD_GlcNHglycan	320	323	PF01048	0.602
MOD_GlcNHglycan	74	78	PF01048	0.412
MOD_GSK3_1	136	143	PF00069	0.523
MOD_GSK3_1	169	176	PF00069	0.685
MOD_GSK3_1	178	185	PF00069	0.617
MOD_GSK3_1	214	221	PF00069	0.604
MOD_GSK3_1	254	261	PF00069	0.556
MOD_GSK3_1	26	33	PF00069	0.628
MOD_GSK3_1	89	96	PF00069	0.727
MOD_NEK2_1	1	6	PF00069	0.604
MOD_NEK2_1	184	189	PF00069	0.600
MOD_NEK2_1	73	78	PF00069	0.401
MOD_NEK2_2	42	47	PF00069	0.507
MOD_PIKK_1	30	36	PF00454	0.591
MOD_PKA_2	254	260	PF00069	0.592
MOD_PKA_2	309	315	PF00069	0.697
MOD_PKA_2	327	333	PF00069	0.707
MOD_PKA_2	93	99	PF00069	0.575
MOD_Plk_1	73	79	PF00069	0.487
MOD_ProDKin_1	192	198	PF00069	0.670
MOD_ProDKin_1	2	8	PF00069	0.598
MOD_ProDKin_1	207	213	PF00069	0.496
MOD_ProDKin_1	21	27	PF00069	0.550
MOD_ProDKin_1	34	40	PF00069	0.484
TRG_ER_diArg_1	285	287	PF00400	0.584

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4T4	Leptomonas seymouri	34%	95%
A0A3S7WQV7	Leishmania donovani	98%	100%
A4H5V9	Leishmania braziliensis	66%	100%
E9ACQ8	Leishmania major	93%	100%
E9AMY3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%