LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Surface antigen-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Surface antigen-like protein
Gene product:
surface antigen-like protein
Species:
Leishmania infantum
UniProt:
E9AG65_LEIIN
TriTrypDb:
LINF_050017500
Length:
284

Annotations

Annotations by Jardim et al.

Plasma membrane, Surface antigen-like

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 55
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 16
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 24, no: 5
NetGPI no yes: 0, no: 29
Cellular components
Term Name Level Count
GO:0005929 cilium 4 30
GO:0042995 cell projection 2 30
GO:0043226 organelle 2 30
GO:0043227 membrane-bounded organelle 3 30
GO:0110165 cellular anatomical entity 1 30
GO:0120025 plasma membrane bounded cell projection 3 30
GO:0016020 membrane 2 9

Expansion

Sequence features

E9AG65
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AG65

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 96 100 PF00656 0.264
DOC_CDC14_PxL_1 43 51 PF14671 0.253
DOC_MAPK_gen_1 126 135 PF00069 0.356
DOC_MAPK_MEF2A_6 44 51 PF00069 0.243
DOC_PP1_RVXF_1 130 136 PF00149 0.273
DOC_USP7_MATH_1 192 196 PF00917 0.368
DOC_USP7_MATH_1 21 25 PF00917 0.610
DOC_USP7_MATH_1 278 282 PF00917 0.249
DOC_USP7_MATH_1 69 73 PF00917 0.326
DOC_USP7_MATH_2 145 151 PF00917 0.277
DOC_USP7_UBL2_3 40 44 PF12436 0.276
LIG_14-3-3_CanoR_1 244 253 PF00244 0.365
LIG_BIR_II_1 1 5 PF00653 0.637
LIG_BRCT_BRCA1_1 155 159 PF00533 0.232
LIG_BRCT_BRCA1_1 239 243 PF00533 0.308
LIG_BRCT_BRCA1_1 280 284 PF00533 0.223
LIG_BRCT_BRCA1_1 81 85 PF00533 0.416
LIG_Clathr_ClatBox_1 154 158 PF01394 0.251
LIG_FHA_1 115 121 PF00498 0.414
LIG_FHA_1 26 32 PF00498 0.371
LIG_FHA_1 267 273 PF00498 0.290
LIG_FHA_1 68 74 PF00498 0.392
LIG_FHA_1 9 15 PF00498 0.476
LIG_FHA_2 129 135 PF00498 0.427
LIG_FHA_2 88 94 PF00498 0.385
LIG_LIR_Gen_1 123 130 PF02991 0.311
LIG_LIR_Gen_1 195 204 PF02991 0.354
LIG_LIR_Gen_1 35 46 PF02991 0.388
LIG_LIR_Gen_1 4 14 PF02991 0.444
LIG_LIR_Gen_1 82 92 PF02991 0.288
LIG_LIR_Nem_3 123 127 PF02991 0.306
LIG_LIR_Nem_3 160 166 PF02991 0.377
LIG_LIR_Nem_3 195 200 PF02991 0.341
LIG_LIR_Nem_3 4 9 PF02991 0.446
LIG_LIR_Nem_3 82 88 PF02991 0.309
LIG_PDZ_Class_2 279 284 PF00595 0.419
LIG_Pex14_2 193 197 PF04695 0.252
LIG_PTB_Apo_2 158 165 PF02174 0.232
LIG_SH2_CRK 166 170 PF00017 0.243
LIG_SH2_STAT5 163 166 PF00017 0.408
LIG_SH2_STAT5 253 256 PF00017 0.277
LIG_SH3_3 17 23 PF00018 0.497
LIG_SH3_3 252 258 PF00018 0.374
LIG_Sin3_3 15 22 PF02671 0.411
LIG_SUMO_SIM_par_1 153 158 PF11976 0.333
LIG_SUMO_SIM_par_1 275 281 PF11976 0.288
MOD_CK1_1 125 131 PF00069 0.340
MOD_CK1_1 150 156 PF00069 0.310
MOD_CK1_1 195 201 PF00069 0.346
MOD_CK1_1 220 226 PF00069 0.406
MOD_CK1_1 245 251 PF00069 0.387
MOD_CK1_1 25 31 PF00069 0.458
MOD_CK1_1 4 10 PF00069 0.451
MOD_CK2_1 87 93 PF00069 0.408
MOD_GlcNHglycan 140 143 PF01048 0.539
MOD_GlcNHglycan 24 27 PF01048 0.636
MOD_GlcNHglycan 247 250 PF01048 0.506
MOD_GlcNHglycan 67 70 PF01048 0.516
MOD_GSK3_1 116 123 PF00069 0.317
MOD_GSK3_1 153 160 PF00069 0.255
MOD_GSK3_1 192 199 PF00069 0.325
MOD_GSK3_1 21 28 PF00069 0.647
MOD_GSK3_1 216 223 PF00069 0.323
MOD_GSK3_1 245 252 PF00069 0.355
MOD_GSK3_1 4 11 PF00069 0.425
MOD_GSK3_1 65 72 PF00069 0.333
MOD_N-GLC_1 171 176 PF02516 0.527
MOD_N-GLC_2 57 59 PF02516 0.443
MOD_NEK2_1 1 6 PF00069 0.471
MOD_NEK2_1 103 108 PF00069 0.377
MOD_NEK2_1 116 121 PF00069 0.377
MOD_NEK2_1 133 138 PF00069 0.292
MOD_NEK2_1 159 164 PF00069 0.312
MOD_NEK2_1 193 198 PF00069 0.326
MOD_NEK2_1 206 211 PF00069 0.290
MOD_NEK2_1 8 13 PF00069 0.596
MOD_NEK2_1 87 92 PF00069 0.372
MOD_PIKK_1 177 183 PF00454 0.347
MOD_PIKK_1 32 38 PF00454 0.349
MOD_PKA_2 114 120 PF00069 0.291
MOD_PKA_2 125 131 PF00069 0.260
MOD_PKA_2 138 144 PF00069 0.341
MOD_Plk_1 171 177 PF00069 0.277
MOD_Plk_1 94 100 PF00069 0.432
MOD_Plk_4 150 156 PF00069 0.381
MOD_Plk_4 159 165 PF00069 0.367
MOD_Plk_4 278 284 PF00069 0.286
MOD_SUMO_rev_2 219 225 PF00179 0.306
TRG_ER_diArg_1 137 140 PF00400 0.271
TRG_NES_CRM1_1 146 158 PF08389 0.240

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2E6 Leptomonas seymouri 28% 100%
A0A0N0P2L4 Leptomonas seymouri 27% 96%
A0A0N0P4M2 Leptomonas seymouri 32% 100%
A0A0S4IVH1 Bodo saltans 28% 100%
A0A1X0NKN8 Trypanosomatidae 39% 99%
A0A3Q8I9A6 Leishmania donovani 23% 74%
A0A3Q8I9D0 Leishmania donovani 28% 100%
A0A3Q8IIJ9 Leishmania donovani 25% 94%
A0A3S5H6D6 Leishmania donovani 28% 100%
A0A3S7WP69 Leishmania donovani 32% 99%
A0A3S7WPB2 Leishmania donovani 100% 100%
A0A3S7X4J4 Leishmania donovani 25% 94%
A4H4D2 Leishmania braziliensis 29% 100%
A4H4G6 Leishmania braziliensis 80% 100%
A4H5P0 Leishmania braziliensis 30% 100%
A4HJC8 Leishmania braziliensis 21% 100%
A4HSL2 Leishmania infantum 33% 100%
A4HTX9 Leishmania infantum 28% 100%
A4HVB0 Leishmania infantum 24% 70%
A4I6S4 Leishmania infantum 25% 100%
E8NHP8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 94%
E9ACQ0 Leishmania major 94% 100%
E9AGG5 Leishmania infantum 24% 68%
E9AGH0 Leishmania infantum 26% 75%
E9AKJ6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 100%
E9AKM8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
E9AMQ9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9AP02 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 100%
E9AP03 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 100%
E9AP07 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 100%
E9AP08 Leishmania mexicana (strain MHOM/GT/2001/U1103) 22% 68%
E9B1U4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 83%
E9B1U5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 68%
E9B1U6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 94%
P58822 Phaseolus vulgaris 26% 83%
Q25331 Leishmania major 30% 74%
Q4Q6B6 Leishmania major 26% 94%
Q4Q6B7 Leishmania major 26% 94%
Q4QGJ4 Leishmania major 30% 74%
Q4QGJ7 Leishmania major 30% 76%
Q4QGK6 Leishmania major 30% 74%
Q4QGL4 Leishmania major 28% 72%
Q4QHW6 Leishmania major 29% 100%
Q4QJB2 Leishmania major 30% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS