Phosphate transporter

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphate-Repressible Phosphate Permease-like protein

Species:

Leishmania infantum

UniProt:

E9AG39_LEIIN

TriTrypDb:

LINF_030009800

Length:

572

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 23
NetGPI	no	yes: 0, no: 23

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	24
GO:0110165	cellular anatomical entity	1	24

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Expansion

Sequence features

E9AG39

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AG39

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	24
GO:0006811	monoatomic ion transport	4	24
GO:0006817	phosphate ion transport	7	24
GO:0006820	monoatomic anion transport	5	24
GO:0009987	cellular process	1	3
GO:0015698	inorganic anion transport	6	24
GO:0034220	monoatomic ion transmembrane transport	3	3
GO:0035435	phosphate ion transmembrane transport	6	3
GO:0051179	localization	1	24
GO:0051234	establishment of localization	2	24

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Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	24
GO:0005315	inorganic phosphate transmembrane transporter activity	4	24
GO:0015291	secondary active transmembrane transporter activity	4	24
GO:0015293	symporter activity	5	24
GO:0015318	inorganic molecular entity transmembrane transporter activity	3	24
GO:0022804	active transmembrane transporter activity	3	24
GO:0022857	transmembrane transporter activity	2	24

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	351	355	PF00656	0.532
CLV_C14_Caspase3-7	369	373	PF00656	0.348
CLV_NRD_NRD_1	138	140	PF00675	0.509
CLV_NRD_NRD_1	247	249	PF00675	0.218
CLV_NRD_NRD_1	289	291	PF00675	0.239
CLV_NRD_NRD_1	302	304	PF00675	0.177
CLV_NRD_NRD_1	530	532	PF00675	0.233
CLV_PCSK_KEX2_1	246	248	PF00082	0.262
CLV_PCSK_KEX2_1	289	291	PF00082	0.205
CLV_PCSK_KEX2_1	302	304	PF00082	0.177

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4S5	Leptomonas seymouri	49%	100%
A0A0S4JEW4	Bodo saltans	26%	90%
A0A1X0NXY5	Trypanosomatidae	48%	100%
A0A3Q8I8Y3	Leishmania donovani	49%	100%
A0A3Q8IBK1	Leishmania donovani	46%	100%
A0A3R7K4N2	Trypanosoma rangeli	44%	100%
A0A3R7L5P3	Trypanosoma rangeli	25%	95%
A0A3S5H545	Leishmania donovani	100%	100%
A4H5Y5	Leishmania braziliensis	47%	87%
A4H6C2	Leishmania braziliensis	47%	87%

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