Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AG35_LEIIN

TriTrypDb:

LINF_030009300

Length:

1060

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AG35

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AG35

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	165	169	PF00656	0.566
CLV_C14_Caspase3-7	549	553	PF00656	0.584
CLV_C14_Caspase3-7	558	562	PF00656	0.538
CLV_C14_Caspase3-7	768	772	PF00656	0.601
CLV_C14_Caspase3-7	91	95	PF00656	0.681
CLV_NRD_NRD_1	123	125	PF00675	0.725
CLV_NRD_NRD_1	202	204	PF00675	0.707
CLV_NRD_NRD_1	461	463	PF00675	0.614
CLV_NRD_NRD_1	920	922	PF00675	0.615
CLV_NRD_NRD_1	985	987	PF00675	0.557
CLV_PCSK_FUR_1	918	922	PF00082	0.606
CLV_PCSK_KEX2_1	123	125	PF00082	0.725
CLV_PCSK_KEX2_1	202	204	PF00082	0.710
CLV_PCSK_KEX2_1	461	463	PF00082	0.614
CLV_PCSK_KEX2_1	920	922	PF00082	0.689
CLV_PCSK_KEX2_1	985	987	PF00082	0.557
CLV_PCSK_PC7_1	198	204	PF00082	0.731
CLV_PCSK_SKI1_1	136	140	PF00082	0.711
CLV_PCSK_SKI1_1	551	555	PF00082	0.685
CLV_PCSK_SKI1_1	659	663	PF00082	0.561
CLV_PCSK_SKI1_1	920	924	PF00082	0.691
DEG_APCC_DBOX_1	585	593	PF00400	0.620
DEG_Nend_Nbox_1	1	3	PF02207	0.682
DEG_SPOP_SBC_1	571	575	PF00917	0.640
DOC_CKS1_1	231	236	PF01111	0.707
DOC_CKS1_1	457	462	PF01111	0.694
DOC_CKS1_1	46	51	PF01111	0.664
DOC_CKS1_1	535	540	PF01111	0.680
DOC_CKS1_1	76	81	PF01111	0.673
DOC_CKS1_1	781	786	PF01111	0.684
DOC_CYCLIN_RxL_1	133	143	PF00134	0.704
DOC_MAPK_gen_1	202	213	PF00069	0.676
DOC_MAPK_MEF2A_6	173	180	PF00069	0.650
DOC_MAPK_MEF2A_6	206	215	PF00069	0.674
DOC_PP2B_LxvP_1	1010	1013	PF13499	0.688
DOC_PP2B_LxvP_1	129	132	PF13499	0.709
DOC_PP2B_LxvP_1	215	218	PF13499	0.639
DOC_PP2B_LxvP_1	252	255	PF13499	0.745
DOC_PP2B_PxIxI_1	537	543	PF00149	0.657
DOC_PP4_MxPP_1	242	245	PF00568	0.631
DOC_USP7_MATH_1	134	138	PF00917	0.666
DOC_USP7_MATH_1	14	18	PF00917	0.601
DOC_USP7_MATH_1	152	156	PF00917	0.546
DOC_USP7_MATH_1	270	274	PF00917	0.648
DOC_USP7_MATH_1	431	435	PF00917	0.773
DOC_USP7_MATH_1	522	526	PF00917	0.702
DOC_USP7_MATH_1	570	574	PF00917	0.653
DOC_USP7_MATH_1	593	597	PF00917	0.593
DOC_USP7_MATH_1	626	630	PF00917	0.606
DOC_USP7_MATH_1	694	698	PF00917	0.578
DOC_USP7_MATH_1	836	840	PF00917	0.594
DOC_USP7_MATH_1	852	856	PF00917	0.486
DOC_USP7_MATH_1	937	941	PF00917	0.688
DOC_USP7_MATH_1	960	964	PF00917	0.613
DOC_USP7_MATH_1	995	999	PF00917	0.635
DOC_WW_Pin1_4	100	105	PF00397	0.724
DOC_WW_Pin1_4	110	115	PF00397	0.635
DOC_WW_Pin1_4	166	171	PF00397	0.560
DOC_WW_Pin1_4	230	235	PF00397	0.710
DOC_WW_Pin1_4	30	35	PF00397	0.700
DOC_WW_Pin1_4	334	339	PF00397	0.631
DOC_WW_Pin1_4	359	364	PF00397	0.692
DOC_WW_Pin1_4	368	373	PF00397	0.617
DOC_WW_Pin1_4	384	389	PF00397	0.519
DOC_WW_Pin1_4	399	404	PF00397	0.547
DOC_WW_Pin1_4	41	46	PF00397	0.651
DOC_WW_Pin1_4	423	428	PF00397	0.738
DOC_WW_Pin1_4	445	450	PF00397	0.842
DOC_WW_Pin1_4	456	461	PF00397	0.692
DOC_WW_Pin1_4	481	486	PF00397	0.657
DOC_WW_Pin1_4	501	506	PF00397	0.710
DOC_WW_Pin1_4	511	516	PF00397	0.688
DOC_WW_Pin1_4	534	539	PF00397	0.677
DOC_WW_Pin1_4	543	548	PF00397	0.590
DOC_WW_Pin1_4	678	683	PF00397	0.645
DOC_WW_Pin1_4	690	695	PF00397	0.613
DOC_WW_Pin1_4	699	704	PF00397	0.610
DOC_WW_Pin1_4	719	724	PF00397	0.517
DOC_WW_Pin1_4	75	80	PF00397	0.671
DOC_WW_Pin1_4	760	765	PF00397	0.656
DOC_WW_Pin1_4	780	785	PF00397	0.491
DOC_WW_Pin1_4	797	802	PF00397	0.529
DOC_WW_Pin1_4	845	850	PF00397	0.663
DOC_WW_Pin1_4	865	870	PF00397	0.548
LIG_14-3-3_CanoR_1	1048	1054	PF00244	0.569
LIG_14-3-3_CanoR_1	123	133	PF00244	0.628
LIG_14-3-3_CanoR_1	136	141	PF00244	0.583
LIG_14-3-3_CanoR_1	144	148	PF00244	0.621
LIG_14-3-3_CanoR_1	37	43	PF00244	0.605
LIG_14-3-3_CanoR_1	433	438	PF00244	0.667
LIG_14-3-3_CanoR_1	521	527	PF00244	0.580
LIG_14-3-3_CanoR_1	586	590	PF00244	0.644
LIG_14-3-3_CanoR_1	659	668	PF00244	0.554
LIG_14-3-3_CanoR_1	688	694	PF00244	0.652
LIG_14-3-3_CanoR_1	739	745	PF00244	0.654
LIG_APCC_ABBA_1	610	615	PF00400	0.616
LIG_BIR_III_4	771	775	PF00653	0.630
LIG_BRCT_BRCA1_1	843	847	PF00533	0.550
LIG_deltaCOP1_diTrp_1	561	566	PF00928	0.686
LIG_deltaCOP1_diTrp_1	796	804	PF00928	0.690
LIG_EVH1_1	129	133	PF00568	0.707
LIG_FHA_1	159	165	PF00498	0.690
LIG_FHA_1	293	299	PF00498	0.570
LIG_FHA_1	371	377	PF00498	0.590
LIG_FHA_1	535	541	PF00498	0.680
LIG_FHA_1	720	726	PF00498	0.664
LIG_FHA_1	739	745	PF00498	0.629
LIG_FHA_1	888	894	PF00498	0.682
LIG_FHA_1	959	965	PF00498	0.639
LIG_FHA_2	231	237	PF00498	0.661
LIG_FHA_2	502	508	PF00498	0.773
LIG_FHA_2	547	553	PF00498	0.635
LIG_FHA_2	556	562	PF00498	0.569
LIG_FHA_2	879	885	PF00498	0.586
LIG_LIR_Apic_2	371	377	PF02991	0.735
LIG_LIR_Apic_2	399	403	PF02991	0.783
LIG_LIR_Apic_2	697	703	PF02991	0.684
LIG_LIR_Apic_2	796	801	PF02991	0.690
LIG_LIR_Gen_1	848	859	PF02991	0.623
LIG_LIR_Gen_1	901	909	PF02991	0.578
LIG_LIR_Nem_3	246	250	PF02991	0.752
LIG_LIR_Nem_3	300	306	PF02991	0.635
LIG_LIR_Nem_3	628	634	PF02991	0.551
LIG_LIR_Nem_3	848	854	PF02991	0.650
LIG_LIR_Nem_3	855	859	PF02991	0.573
LIG_LIR_Nem_3	901	905	PF02991	0.579
LIG_NRBOX	902	908	PF00104	0.576
LIG_PTAP_UEV_1	484	489	PF05743	0.556
LIG_SH2_CRK	374	378	PF00017	0.670
LIG_SH2_CRK	851	855	PF00017	0.597
LIG_SH2_NCK_1	851	855	PF00017	0.642
LIG_SH2_STAT3	117	120	PF00017	0.606
LIG_SH2_STAT3	417	420	PF00017	0.539
LIG_SH2_STAT3	701	704	PF00017	0.682
LIG_SH2_STAT5	631	634	PF00017	0.558
LIG_SH3_1	43	49	PF00018	0.684
LIG_SH3_2	457	462	PF14604	0.614
LIG_SH3_3	106	112	PF00018	0.630
LIG_SH3_3	127	133	PF00018	0.707
LIG_SH3_3	17	23	PF00018	0.637
LIG_SH3_3	302	308	PF00018	0.640
LIG_SH3_3	43	49	PF00018	0.729
LIG_SH3_3	454	460	PF00018	0.707
LIG_SH3_3	464	470	PF00018	0.579
LIG_SH3_3	479	485	PF00018	0.513
LIG_SH3_3	741	747	PF00018	0.632
LIG_SH3_3	994	1000	PF00018	0.705
LIG_SUMO_SIM_anti_2	901	907	PF11976	0.576
LIG_SUMO_SIM_par_1	680	687	PF11976	0.617
LIG_SUMO_SIM_par_1	889	894	PF11976	0.679
LIG_TRAF2_1	182	185	PF00917	0.714
LIG_TRAF2_1	491	494	PF00917	0.635
LIG_TRAF2_2	806	811	PF00917	0.628
LIG_UBA3_1	292	297	PF00899	0.645
LIG_WW_1	244	247	PF00397	0.631
LIG_WW_1	86	89	PF00397	0.716
MOD_CDC14_SPxK_1	362	365	PF00782	0.678
MOD_CDK_SPK_2	105	110	PF00069	0.683
MOD_CDK_SPK_2	334	339	PF00069	0.575
MOD_CDK_SPK_2	456	461	PF00069	0.736
MOD_CDK_SPK_2	75	80	PF00069	0.671
MOD_CDK_SPK_2	780	785	PF00069	0.559
MOD_CDK_SPxK_1	359	365	PF00069	0.680
MOD_CDK_SPxK_1	449	455	PF00069	0.724
MOD_CDK_SPxK_1	456	462	PF00069	0.669
MOD_CDK_SPxK_1	760	766	PF00069	0.659
MOD_CDK_SPxxK_3	100	107	PF00069	0.680
MOD_CDK_SPxxK_3	166	173	PF00069	0.558
MOD_CDK_SPxxK_3	30	37	PF00069	0.669
MOD_CDK_SPxxK_3	368	375	PF00069	0.695
MOD_CDK_SPxxK_3	45	52	PF00069	0.593
MOD_CDK_SPxxK_3	719	726	PF00069	0.639
MOD_CK1_1	169	175	PF00069	0.602
MOD_CK1_1	274	280	PF00069	0.687
MOD_CK1_1	28	34	PF00069	0.686
MOD_CK1_1	41	47	PF00069	0.646
MOD_CK1_1	448	454	PF00069	0.719
MOD_CK1_1	486	492	PF00069	0.814
MOD_CK1_1	575	581	PF00069	0.586
MOD_CK1_1	591	597	PF00069	0.588
MOD_CK1_1	681	687	PF00069	0.698
MOD_CK1_1	689	695	PF00069	0.619
MOD_CK1_1	745	751	PF00069	0.652
MOD_CK1_1	843	849	PF00069	0.670
MOD_CK1_1	850	856	PF00069	0.601
MOD_CK1_1	887	893	PF00069	0.691
MOD_CK1_1	90	96	PF00069	0.725
MOD_CK1_1	941	947	PF00069	0.673
MOD_CK1_1	998	1004	PF00069	0.687
MOD_CK2_1	2	8	PF00069	0.650
MOD_CK2_1	353	359	PF00069	0.643
MOD_CK2_1	501	507	PF00069	0.686
MOD_CK2_1	790	796	PF00069	0.603
MOD_CK2_1	873	879	PF00069	0.709
MOD_CK2_1	94	100	PF00069	0.680
MOD_GlcNHglycan	1021	1024	PF01048	0.605
MOD_GlcNHglycan	1049	1052	PF01048	0.582
MOD_GlcNHglycan	187	190	PF01048	0.644
MOD_GlcNHglycan	215	218	PF01048	0.633
MOD_GlcNHglycan	27	30	PF01048	0.665
MOD_GlcNHglycan	315	318	PF01048	0.694
MOD_GlcNHglycan	355	358	PF01048	0.684
MOD_GlcNHglycan	393	396	PF01048	0.714
MOD_GlcNHglycan	4	7	PF01048	0.648
MOD_GlcNHglycan	485	488	PF01048	0.691
MOD_GlcNHglycan	516	519	PF01048	0.638
MOD_GlcNHglycan	568	571	PF01048	0.638
MOD_GlcNHglycan	595	598	PF01048	0.681
MOD_GlcNHglycan	628	631	PF01048	0.603
MOD_GlcNHglycan	688	691	PF01048	0.671
MOD_GlcNHglycan	713	716	PF01048	0.657
MOD_GlcNHglycan	751	754	PF01048	0.589
MOD_GlcNHglycan	785	788	PF01048	0.654
MOD_GlcNHglycan	792	795	PF01048	0.591
MOD_GlcNHglycan	915	918	PF01048	0.576
MOD_GlcNHglycan	925	929	PF01048	0.559
MOD_GlcNHglycan	943	946	PF01048	0.646
MOD_GlcNHglycan	96	99	PF01048	0.712
MOD_GlcNHglycan	973	978	PF01048	0.619
MOD_GSK3_1	134	141	PF00069	0.700
MOD_GSK3_1	185	192	PF00069	0.658
MOD_GSK3_1	2	9	PF00069	0.666
MOD_GSK3_1	202	209	PF00069	0.619
MOD_GSK3_1	270	277	PF00069	0.684
MOD_GSK3_1	349	356	PF00069	0.559
MOD_GSK3_1	380	387	PF00069	0.621
MOD_GSK3_1	41	48	PF00069	0.662
MOD_GSK3_1	422	429	PF00069	0.791
MOD_GSK3_1	433	440	PF00069	0.557
MOD_GSK3_1	445	452	PF00069	0.657
MOD_GSK3_1	566	573	PF00069	0.596
MOD_GSK3_1	584	591	PF00069	0.547
MOD_GSK3_1	684	691	PF00069	0.691
MOD_GSK3_1	695	702	PF00069	0.553
MOD_GSK3_1	711	718	PF00069	0.617
MOD_GSK3_1	738	745	PF00069	0.653
MOD_GSK3_1	751	758	PF00069	0.564
MOD_GSK3_1	779	786	PF00069	0.639
MOD_GSK3_1	836	843	PF00069	0.651
MOD_GSK3_1	878	885	PF00069	0.632
MOD_GSK3_1	90	97	PF00069	0.690
MOD_GSK3_1	937	944	PF00069	0.692
MOD_GSK3_1	948	955	PF00069	0.543
MOD_GSK3_1	998	1005	PF00069	0.670
MOD_LATS_1	122	128	PF00433	0.721
MOD_LATS_1	200	206	PF00433	0.729
MOD_LATS_1	871	877	PF00433	0.661
MOD_N-GLC_1	339	344	PF02516	0.592
MOD_N-GLC_1	913	918	PF02516	0.574
MOD_NEK2_1	1002	1007	PF00069	0.570
MOD_NEK2_1	1049	1054	PF00069	0.459
MOD_NEK2_1	2	7	PF00069	0.664
MOD_NEK2_1	213	218	PF00069	0.588
MOD_NEK2_1	292	297	PF00069	0.578
MOD_NEK2_1	391	396	PF00069	0.581
MOD_NEK2_1	432	437	PF00069	0.702
MOD_NEK2_1	554	559	PF00069	0.680
MOD_NEK2_1	566	571	PF00069	0.566
MOD_NEK2_1	624	629	PF00069	0.620
MOD_NEK2_1	670	675	PF00069	0.554
MOD_NEK2_1	711	716	PF00069	0.634
MOD_NEK2_1	765	770	PF00069	0.621
MOD_NEK2_2	38	43	PF00069	0.603
MOD_NEK2_2	6	11	PF00069	0.644
MOD_PIKK_1	275	281	PF00454	0.691
MOD_PIKK_1	670	676	PF00454	0.520
MOD_PIKK_1	742	748	PF00454	0.699
MOD_PIKK_1	884	890	PF00454	0.702
MOD_PK_1	433	439	PF00069	0.695
MOD_PK_1	882	888	PF00069	0.683
MOD_PKA_1	202	208	PF00069	0.710
MOD_PKA_2	1047	1053	PF00069	0.565
MOD_PKA_2	125	131	PF00069	0.613
MOD_PKA_2	143	149	PF00069	0.523
MOD_PKA_2	202	208	PF00069	0.709
MOD_PKA_2	23	29	PF00069	0.620
MOD_PKA_2	321	327	PF00069	0.646
MOD_PKA_2	36	42	PF00069	0.571
MOD_PKA_2	432	438	PF00069	0.668
MOD_PKA_2	585	591	PF00069	0.645
MOD_PKA_2	738	744	PF00069	0.654
MOD_PKA_2	765	771	PF00069	0.622
MOD_Plk_1	882	888	PF00069	0.706
MOD_Plk_4	536	542	PF00069	0.681
MOD_Plk_4	695	701	PF00069	0.643
MOD_Plk_4	751	757	PF00069	0.615
MOD_Plk_4	960	966	PF00069	0.606
MOD_ProDKin_1	100	106	PF00069	0.724
MOD_ProDKin_1	110	116	PF00069	0.636
MOD_ProDKin_1	166	172	PF00069	0.559
MOD_ProDKin_1	230	236	PF00069	0.707
MOD_ProDKin_1	30	36	PF00069	0.701
MOD_ProDKin_1	334	340	PF00069	0.628
MOD_ProDKin_1	359	365	PF00069	0.692
MOD_ProDKin_1	368	374	PF00069	0.618
MOD_ProDKin_1	384	390	PF00069	0.519
MOD_ProDKin_1	399	405	PF00069	0.549
MOD_ProDKin_1	41	47	PF00069	0.651
MOD_ProDKin_1	423	429	PF00069	0.739
MOD_ProDKin_1	445	451	PF00069	0.844
MOD_ProDKin_1	456	462	PF00069	0.692
MOD_ProDKin_1	481	487	PF00069	0.658
MOD_ProDKin_1	501	507	PF00069	0.713
MOD_ProDKin_1	511	517	PF00069	0.688
MOD_ProDKin_1	534	540	PF00069	0.677
MOD_ProDKin_1	543	549	PF00069	0.592
MOD_ProDKin_1	678	684	PF00069	0.649
MOD_ProDKin_1	690	696	PF00069	0.613
MOD_ProDKin_1	699	705	PF00069	0.609
MOD_ProDKin_1	719	725	PF00069	0.516
MOD_ProDKin_1	75	81	PF00069	0.671
MOD_ProDKin_1	760	766	PF00069	0.659
MOD_ProDKin_1	780	786	PF00069	0.490
MOD_ProDKin_1	797	803	PF00069	0.527
MOD_ProDKin_1	845	851	PF00069	0.663
MOD_ProDKin_1	865	871	PF00069	0.550
MOD_SUMO_rev_2	221	229	PF00179	0.642
TRG_DiLeu_BaEn_1	901	906	PF01217	0.578
TRG_ENDOCYTIC_2	851	854	PF00928	0.625
TRG_ER_diArg_1	1039	1042	PF00400	0.565
TRG_ER_diArg_1	1046	1049	PF00400	0.503
TRG_ER_diArg_1	123	125	PF00400	0.725
TRG_ER_diArg_1	460	462	PF00400	0.614
TRG_ER_diArg_1	725	728	PF00400	0.630
TRG_ER_diArg_1	918	921	PF00400	0.604
TRG_ER_diArg_1	985	988	PF00400	0.554
TRG_Pf-PMV_PEXEL_1	921	925	PF00026	0.617

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJP7	Leishmania donovani	99%	100%
A4H3R6	Leishmania braziliensis	62%	97%
E9ACJ1	Leishmania major	86%	100%
E9AJS9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	99%