Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

E9AG33_LEIIN

TriTrypDb:

LINF_030006200

Length:

139

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AG33

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AG33

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	110	112	PF00675	0.646
CLV_NRD_NRD_1	121	123	PF00675	0.431
CLV_NRD_NRD_1	32	34	PF00675	0.522
CLV_PCSK_FUR_1	108	112	PF00082	0.642
CLV_PCSK_KEX2_1	110	112	PF00082	0.623
CLV_PCSK_KEX2_1	31	33	PF00082	0.523
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.552
CLV_PCSK_SKI1_1	111	115	PF00082	0.550
DEG_APCC_DBOX_1	110	118	PF00400	0.623
DOC_MAPK_gen_1	120	129	PF00069	0.550
DOC_MAPK_MEF2A_6	62	69	PF00069	0.587
DOC_MAPK_NFAT4_5	62	70	PF00069	0.664
DOC_USP7_MATH_1	86	90	PF00917	0.703
DOC_USP7_MATH_1	92	96	PF00917	0.686
DOC_USP7_UBL2_3	68	72	PF12436	0.703
LIG_14-3-3_CanoR_1	110	118	PF00244	0.540
LIG_LIR_Gen_1	38	48	PF02991	0.527
LIG_LIR_Nem_3	38	44	PF02991	0.492
LIG_SH2_CRK	23	27	PF00017	0.618
LIG_SH2_STAT5	13	16	PF00017	0.553
LIG_SH2_STAT5	43	46	PF00017	0.559
LIG_TRAF2_1	113	116	PF00917	0.619
MOD_CK1_1	6	12	PF00069	0.564
MOD_CK2_1	96	102	PF00069	0.539
MOD_GlcNHglycan	5	8	PF01048	0.578
MOD_GlcNHglycan	88	91	PF01048	0.666
MOD_GSK3_1	92	99	PF00069	0.674
MOD_PIKK_1	96	102	PF00454	0.630
MOD_PKA_2	109	115	PF00069	0.532
MOD_PKA_2	9	15	PF00069	0.541
MOD_Plk_1	92	98	PF00069	0.568
MOD_Plk_4	9	15	PF00069	0.579
TRG_ENDOCYTIC_2	23	26	PF00928	0.653
TRG_ER_diArg_1	62	65	PF00400	0.562

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJS5	Leptomonas seymouri	57%	97%
A0A0S4JDM7	Bodo saltans	43%	100%
A0A1X0P8N0	Trypanosomatidae	47%	100%
A0A422N7L0	Trypanosoma rangeli	46%	100%
A0A451EJL9	Leishmania donovani	99%	100%
A4H3I6	Leishmania braziliensis	80%	100%
D0A221	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
E9ACG1	Leishmania major	96%	100%
E9AJP9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%