LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania major
UniProt:
E9AG14_LEIMA
TriTrypDb:
LmjF.36.1265
Length:
134

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 3
GO:0110165 cellular anatomical entity 1 3
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Expansion

Sequence features

E9AG14
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AG14

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 122 124 PF00675 0.411
CLV_PCSK_KEX2_1 122 124 PF00082 0.411
CLV_PCSK_KEX2_1 128 130 PF00082 0.405
CLV_PCSK_PC1ET2_1 122 124 PF00082 0.411
CLV_PCSK_PC1ET2_1 128 130 PF00082 0.405
CLV_PCSK_SKI1_1 129 133 PF00082 0.408
DEG_APCC_KENBOX_2 84 88 PF00400 0.647
DEG_Nend_UBRbox_2 1 3 PF02207 0.645
DOC_CYCLIN_RxL_1 123 134 PF00134 0.609
DOC_MAPK_MEF2A_6 15 23 PF00069 0.435
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IKD2 Leishmania donovani 53% 100%
E9AHX2 Leishmania infantum 40% 95%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS