EF-hand domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AFY0_LEIMA

TriTrypDb:

LmjF.35.5070 , LMJLV39_350058800 , LMJSD75_350058100

Length:

168


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

E9AFY0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFY0


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	108	112	PF00082	0.379
CLV_PCSK_SKI1_1	55	59	PF00082	0.381
CLV_PCSK_SKI1_1	67	71	PF00082	0.398
DOC_MAPK_MEF2A_6	124	132	PF00069	0.455
DOC_PP1_RVXF_1	65	71	PF00149	0.466
DOC_USP7_MATH_1	100	104	PF00917	0.448
DOC_USP7_UBL2_3	108	112	PF12436	0.459
LIG_14-3-3_CanoR_1	78	84	PF00244	0.491
LIG_BIR_II_1	1	5	PF00653	0.574
LIG_BRCT_BRCA1_1	76	80	PF00533	0.520
LIG_Clathr_ClatBox_1	131	135	PF01394	0.453
LIG_deltaCOP1_diTrp_1	85	89	PF00928	0.470
LIG_FHA_1	162	168	PF00498	0.490
LIG_FHA_2	47	53	PF00498	0.509
LIG_FHA_2	80	86	PF00498	0.333
LIG_LIR_Gen_1	85	92	PF02991	0.400
LIG_LIR_Nem_3	135	141	PF02991	0.385
LIG_LIR_Nem_3	157	161	PF02991	0.525
LIG_LIR_Nem_3	51	57	PF02991	0.390
LIG_LIR_Nem_3	77	83	PF02991	0.468
LIG_LIR_Nem_3	85	89	PF02991	0.382
LIG_REV1ctd_RIR_1	108	116	PF16727	0.393
LIG_SH2_CRK	158	162	PF00017	0.565
LIG_SH2_NCK_1	143	147	PF00017	0.491
LIG_SH2_STAP1	115	119	PF00017	0.377
LIG_SH2_STAT5	141	144	PF00017	0.554
LIG_SH2_STAT5	38	41	PF00017	0.429
LIG_SUMO_SIM_anti_2	5	15	PF11976	0.499
LIG_SUMO_SIM_par_1	127	133	PF11976	0.464
LIG_TRAF2_1	88	91	PF00917	0.443
MOD_CK1_1	2	8	PF00069	0.658
MOD_CK2_1	3	9	PF00069	0.630
MOD_CK2_1	46	52	PF00069	0.502
MOD_CK2_1	79	85	PF00069	0.472
MOD_GlcNHglycan	102	106	PF01048	0.463
MOD_GlcNHglycan	118	122	PF01048	0.401
MOD_GSK3_1	90	97	PF00069	0.518
MOD_N-GLC_1	34	39	PF02516	0.548
MOD_NEK2_1	161	166	PF00069	0.502
MOD_PKA_2	94	100	PF00069	0.631
MOD_Plk_1	34	40	PF00069	0.550
MOD_Plk_2-3	3	9	PF00069	0.658
MOD_Plk_2-3	94	100	PF00069	0.543
MOD_SUMO_for_1	111	114	PF00179	0.397
TRG_DiLeu_BaEn_1	157	162	PF01217	0.532
TRG_ENDOCYTIC_2	143	146	PF00928	0.507
TRG_ENDOCYTIC_2	158	161	PF00928	0.458


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC25	Leptomonas seymouri	76%	100%
A0A0S4JSV4	Bodo saltans	50%	99%
A0A1X0P4T8	Trypanosomatidae	56%	93%
A0A3S7XA39	Leishmania donovani	99%	100%
A0A422ND44	Trypanosoma rangeli	51%	100%
A0A6L0Y1J4	Leishmania infantum	99%	100%
A4HNG9	Leishmania braziliensis	90%	100%
C9ZYE3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
E9B733	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%