Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AFX8_LEIMA

TriTrypDb:

LmjF.35.5050 , LMJLV39_350058600 , LMJSD75_350057900

Length:

648

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AFX8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFX8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	139	143	PF00656	0.638
CLV_NRD_NRD_1	19	21	PF00675	0.779
CLV_NRD_NRD_1	329	331	PF00675	0.579
CLV_NRD_NRD_1	373	375	PF00675	0.666
CLV_NRD_NRD_1	377	379	PF00675	0.637
CLV_NRD_NRD_1	412	414	PF00675	0.638
CLV_NRD_NRD_1	516	518	PF00675	0.712
CLV_NRD_NRD_1	520	522	PF00675	0.705
CLV_NRD_NRD_1	545	547	PF00675	0.700
CLV_NRD_NRD_1	583	585	PF00675	0.720

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H810	Leishmania donovani	86%	100%
A4HNG7	Leishmania braziliensis	59%	100%
A4IC58	Leishmania infantum	85%	100%
E9B731	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%

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