LeishMANIAdb
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Cell division protein ZapD

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Cell division protein ZapD
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
E9AFU5_LEIMA
TriTrypDb:
LmjF.35.4680 , LMJLV39_350055100 * , LMJSD75_350054400
Length:
108

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AFU5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFU5

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_APCC_DBOX_1 79 87 PF00400 0.647
DEG_Nend_UBRbox_2 1 3 PF02207 0.512
DOC_MAPK_gen_1 77 86 PF00069 0.455
DOC_MAPK_MEF2A_6 60 69 PF00069 0.431
LIG_14-3-3_CanoR_1 8 13 PF00244 0.475
LIG_FHA_1 32 38 PF00498 0.597
LIG_FHA_1 62 68 PF00498 0.484
LIG_Integrin_RGD_1 96 98 PF01839 0.556
LIG_LIR_Gen_1 11 21 PF02991 0.482
LIG_LIR_Nem_3 11 16 PF02991 0.461
LIG_MYND_1 100 104 PF01753 0.573
LIG_SUMO_SIM_anti_2 25 31 PF11976 0.516
MOD_CK2_1 8 14 PF00069 0.477
MOD_N-GLC_1 31 36 PF02516 0.637
MOD_NEK2_1 61 66 PF00069 0.480
MOD_PK_1 8 14 PF00069 0.477
MOD_Plk_1 25 31 PF00069 0.646
MOD_Plk_1 49 55 PF00069 0.471
MOD_Plk_4 25 31 PF00069 0.518
MOD_Plk_4 61 67 PF00069 0.545
MOD_Plk_4 8 14 PF00069 0.539
MOD_SUMO_for_1 3 6 PF00179 0.467
TRG_DiLeu_BaLyEn_6 97 102 PF01217 0.563
TRG_ENDOCYTIC_2 59 62 PF00928 0.567
TRG_ER_diArg_1 102 105 PF00400 0.577
TRG_Pf-PMV_PEXEL_1 77 81 PF00026 0.589

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IGP3 Leishmania donovani 71% 100%
A4IC07 Leishmania infantum 70% 100%
E9B6Z7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 69% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS