Coiled-coil domain-containing protein 86

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AFU1_LEIMA

TriTrypDb:

LmjF.35.4640 , LMJLV39_350054700 , LMJSD75_350054000

Length:

114


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0043226	organelle	2	9
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	9
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	9
GO:0005634	nucleus	5	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7

E9AFU1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFU1


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	102	104	PF00675	0.270
CLV_NRD_NRD_1	67	69	PF00675	0.281
CLV_NRD_NRD_1	73	75	PF00675	0.287
CLV_NRD_NRD_1	9	11	PF00675	0.467
CLV_NRD_NRD_1	94	96	PF00675	0.305
CLV_PCSK_KEX2_1	102	104	PF00082	0.410
CLV_PCSK_KEX2_1	62	64	PF00082	0.317
CLV_PCSK_PC1ET2_1	62	64	PF00082	0.297
CLV_PCSK_SKI1_1	35	39	PF00082	0.275
DOC_USP7_UBL2_3	26	30	PF12436	0.313
DOC_USP7_UBL2_3	36	40	PF12436	0.304
DOC_USP7_UBL2_3	92	96	PF12436	0.293
DOC_WW_Pin1_4	95	100	PF00397	0.279
LIG_14-3-3_CanoR_1	45	50	PF00244	0.200
LIG_BIR_II_1	1	5	PF00653	0.696
MOD_CDK_SPK_2	95	100	PF00069	0.279
MOD_CDK_SPxxK_3	95	102	PF00069	0.279
MOD_PIKK_1	47	53	PF00454	0.410
MOD_PKB_1	45	53	PF00069	0.279
MOD_ProDKin_1	95	101	PF00069	0.279
MOD_SUMO_for_1	2	5	PF00179	0.654
MOD_SUMO_for_1	53	56	PF00179	0.355
MOD_SUMO_for_1	88	91	PF00179	0.410
MOD_SUMO_rev_2	55	64	PF00179	0.297
MOD_SUMO_rev_2	77	83	PF00179	0.295
TRG_NLS_MonoCore_2	9	14	PF00514	0.464
TRG_NLS_MonoExtC_3	9	15	PF00514	0.466
TRG_NLS_MonoExtN_4	7	14	PF00514	0.470
TRG_Pf-PMV_PEXEL_1	47	51	PF00026	0.327


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMV4	Leptomonas seymouri	82%	100%
A0A0S4JUA2	Bodo saltans	66%	100%
A0A1X0P578	Trypanosomatidae	63%	100%
A0A3R7NTL4	Trypanosoma rangeli	57%	100%
A0A3S7X9Z5	Leishmania donovani	96%	100%
A4HND1	Leishmania braziliensis	89%	100%
A4IC03	Leishmania infantum	96%	100%
C9ZYK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	58%	70%
E9B6Z3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%