LeishMANIAdb
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ARL2_Bind_BART domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
ARL2_Bind_BART domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9AFS5_LEIMA
TriTrypDb:
LmjF.35.4480 , LMJLV39_350053000 * , LMJSD75_350052400 *
Length:
116

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 3
GO:0005929 cilium 4 3
GO:0042995 cell projection 2 3
GO:0043226 organelle 2 3
GO:0043227 membrane-bounded organelle 3 3
GO:0110165 cellular anatomical entity 1 3
GO:0120025 plasma membrane bounded cell projection 3 3

Expansion

Sequence features

E9AFS5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFS5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 20 24 PF00656 0.483
DOC_CKS1_1 15 20 PF01111 0.515
DOC_PP1_SILK_1 103 108 PF00149 0.454
DOC_USP7_MATH_1 24 28 PF00917 0.456
DOC_USP7_MATH_1 61 65 PF00917 0.565
DOC_WW_Pin1_4 14 19 PF00397 0.495
DOC_WW_Pin1_4 4 9 PF00397 0.544
LIG_14-3-3_CanoR_1 39 49 PF00244 0.408
LIG_BIR_II_1 1 5 PF00653 0.556
LIG_Clathr_ClatBox_1 59 63 PF01394 0.453
LIG_CtBP_PxDLS_1 8 12 PF00389 0.531
LIG_FHA_1 24 30 PF00498 0.428
LIG_FHA_1 41 47 PF00498 0.520
LIG_FHA_1 54 60 PF00498 0.520
LIG_FHA_2 1 7 PF00498 0.550
LIG_FHA_2 110 116 PF00498 0.472
LIG_FHA_2 66 72 PF00498 0.532
LIG_LIR_Gen_1 31 37 PF02991 0.395
LIG_LIR_Nem_3 31 36 PF02991 0.527
LIG_Pex14_2 33 37 PF04695 0.388
LIG_REV1ctd_RIR_1 34 43 PF16727 0.389
LIG_SH2_PTP2 83 86 PF00017 0.360
LIG_SH2_STAP1 42 46 PF00017 0.382
LIG_SH2_STAT5 42 45 PF00017 0.384
LIG_SH2_STAT5 83 86 PF00017 0.360
LIG_SH3_3 12 18 PF00018 0.558
LIG_SUMO_SIM_anti_2 55 61 PF11976 0.411
LIG_SUMO_SIM_par_1 5 13 PF11976 0.539
LIG_WRC_WIRS_1 33 38 PF05994 0.392
MOD_CK1_1 10 16 PF00069 0.532
MOD_CK1_1 101 107 PF00069 0.522
MOD_CK2_1 109 115 PF00069 0.492
MOD_CK2_1 65 71 PF00069 0.553
MOD_GlcNHglycan 12 15 PF01048 0.535
MOD_GlcNHglycan 26 29 PF01048 0.491
MOD_GSK3_1 10 17 PF00069 0.531
MOD_GSK3_1 61 68 PF00069 0.584
MOD_GSK3_1 94 101 PF00069 0.504
MOD_NEK2_1 108 113 PF00069 0.524
MOD_Plk_1 101 107 PF00069 0.534
MOD_Plk_4 101 107 PF00069 0.534
MOD_Plk_4 32 38 PF00069 0.392
MOD_ProDKin_1 14 20 PF00069 0.490
MOD_ProDKin_1 4 10 PF00069 0.545
MOD_SUMO_rev_2 20 27 PF00179 0.464
TRG_ENDOCYTIC_2 77 80 PF00928 0.450
TRG_ENDOCYTIC_2 83 86 PF00928 0.386

Homologs

Protein Taxonomy Sequence identity Coverage
A4HNB6 Leishmania braziliensis 63% 69%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS