LeishMANIAdb
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Si:ch211-242b18.1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Si:ch211-242b18.1
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9AFS1_LEIMA
TriTrypDb:
LmjF.35.4440 * , LMJLV39_350052600 * , LMJSD75_350052000 *
Length:
107

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AFS1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFS1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 99 103 PF00656 0.735
CLV_NRD_NRD_1 71 73 PF00675 0.681
CLV_PCSK_KEX2_1 71 73 PF00082 0.681
DEG_APCC_DBOX_1 71 79 PF00400 0.674
DEG_Nend_UBRbox_3 1 3 PF02207 0.689
DOC_PP4_FxxP_1 47 50 PF00568 0.738
DOC_WW_Pin1_4 42 47 PF00397 0.773
LIG_AP2alpha_1 100 104 PF02296 0.643
LIG_APCC_ABBA_1 44 49 PF00400 0.754
LIG_FHA_1 1 7 PF00498 0.605
LIG_FHA_1 16 22 PF00498 0.534
LIG_LIR_Apic_2 45 50 PF02991 0.747
LIG_Pex14_2 100 104 PF04695 0.583
LIG_SH2_CRK 36 40 PF00017 0.512
LIG_SH2_NCK_1 36 40 PF00017 0.512
LIG_WRC_WIRS_1 97 102 PF05994 0.720
MOD_CK1_1 61 67 PF00069 0.546
MOD_CK1_1 96 102 PF00069 0.705
MOD_GlcNHglycan 62 66 PF01048 0.419
MOD_GSK3_1 96 103 PF00069 0.719
MOD_NEK2_1 100 105 PF00069 0.464
MOD_NEK2_1 84 89 PF00069 0.620
MOD_PKA_2 15 21 PF00069 0.552
MOD_PKB_1 20 28 PF00069 0.712
MOD_Plk_1 22 28 PF00069 0.563
MOD_Plk_1 61 67 PF00069 0.570
MOD_ProDKin_1 42 48 PF00069 0.767
MOD_SUMO_for_1 50 53 PF00179 0.710
MOD_SUMO_rev_2 45 52 PF00179 0.737
TRG_DiLeu_BaEn_2 61 67 PF01217 0.670
TRG_ER_diArg_1 70 72 PF00400 0.674

Homologs

Protein Taxonomy Sequence identity Coverage
A4IBY4 Leishmania infantum 89% 100%
E9B6X3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS