Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AFQ8_LEIMA

TriTrypDb:

LmjF.35.4310 , LMJLV39_350051200 , LMJSD75_350050600

Length:

141


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

E9AFQ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFQ8


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_Nbox_1	1	3	PF02207	0.615
DOC_WW_Pin1_4	109	114	PF00397	0.635
DOC_WW_Pin1_4	41	46	PF00397	0.398
LIG_14-3-3_CanoR_1	133	138	PF00244	0.675
LIG_APCC_ABBA_1	89	94	PF00400	0.325
LIG_BRCT_BRCA1_1	3	7	PF00533	0.625
LIG_Clathr_ClatBox_1	90	94	PF01394	0.284
LIG_DLG_GKlike_1	133	141	PF00625	0.628
LIG_FHA_1	12	18	PF00498	0.458
LIG_FHA_1	32	38	PF00498	0.380
LIG_LIR_LC3C_4	14	18	PF02991	0.369
LIG_LIR_LC3C_4	85	88	PF02991	0.325
LIG_NRBOX	85	91	PF00104	0.304
LIG_SH2_GRB2like	118	121	PF00017	0.630
LIG_SH2_STAP1	124	128	PF00017	0.630
LIG_SH2_STAT3	118	121	PF00017	0.599
LIG_SH2_STAT5	25	28	PF00017	0.304
LIG_SH3_1	42	48	PF00018	0.398
LIG_SH3_3	42	48	PF00018	0.426
LIG_SUMO_SIM_anti_2	14	20	PF11976	0.455
LIG_SUMO_SIM_anti_2	85	91	PF11976	0.369
LIG_SUMO_SIM_par_1	14	20	PF11976	0.455
LIG_TYR_ITIM	23	28	PF00017	0.272
LIG_UBA3_1	36	42	PF00899	0.372
MOD_CK1_1	123	129	PF00069	0.559
MOD_GlcNHglycan	64	67	PF01048	0.704
MOD_GlcNHglycan	7	10	PF01048	0.316
MOD_GlcNHglycan	74	77	PF01048	0.430
MOD_GSK3_1	1	8	PF00069	0.651
MOD_N-GLC_1	72	77	PF02516	0.580
MOD_NEK2_1	1	6	PF00069	0.634
MOD_NEK2_1	7	12	PF00069	0.617
MOD_NEK2_1	72	77	PF00069	0.368
MOD_Plk_1	72	78	PF00069	0.269
MOD_Plk_4	1	7	PF00069	0.608
MOD_Plk_4	32	38	PF00069	0.397
MOD_ProDKin_1	109	115	PF00069	0.632
MOD_ProDKin_1	41	47	PF00069	0.397
TRG_ENDOCYTIC_2	25	28	PF00928	0.318
TRG_ER_diLys_1	138	141	PF00400	0.660
TRG_NES_CRM1_1	53	67	PF08389	0.406


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBU8	Leptomonas seymouri	55%	99%
A0A3S7X9Y2	Leishmania donovani	96%	100%
A4HNA0	Leishmania braziliensis	72%	100%
A4IBX1	Leishmania infantum	96%	100%
E9B6W1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%