Mitochondrial fission process protein 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

Present in the outer mitochondrial membrane proteome 6

Species:

Leishmania major

UniProt:

E9AFQ4_LEIMA

TriTrypDb:

LmjF.35.4270 , LMJLV39_350050700 , LMJSD75_350050100

Length:

169


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0000331	contractile vacuole	6	2
GO:0005741	mitochondrial outer membrane	5	2
GO:0005773	vacuole	5	2
GO:0016020	membrane	2	3
GO:0019867	outer membrane	3	2
GO:0031090	organelle membrane	3	2
GO:0031410	cytoplasmic vesicle	6	2
GO:0031966	mitochondrial membrane	4	2
GO:0031968	organelle outer membrane	4	2
GO:0031982	vesicle	4	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0097708	intracellular vesicle	5	2
GO:0098588	bounding membrane of organelle	4	2
GO:0110165	cellular anatomical entity	1	3

E9AFQ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFQ4


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	129	131	PF00675	0.504
CLV_NRD_NRD_1	161	163	PF00675	0.552
CLV_NRD_NRD_1	64	66	PF00675	0.461
CLV_PCSK_FUR_1	159	163	PF00082	0.669
CLV_PCSK_KEX2_1	129	131	PF00082	0.502
CLV_PCSK_KEX2_1	159	161	PF00082	0.533
CLV_PCSK_KEX2_1	64	66	PF00082	0.471
CLV_PCSK_SKI1_1	130	134	PF00082	0.516
DEG_Nend_UBRbox_2	1	3	PF02207	0.543
DOC_CYCLIN_yCln2_LP_2	18	24	PF00134	0.639
DOC_MAPK_gen_1	78	86	PF00069	0.580
DOC_MAPK_MEF2A_6	14	22	PF00069	0.551
DOC_MAPK_MEF2A_6	30	38	PF00069	0.546
DOC_PP2B_LxvP_1	18	21	PF13499	0.576
DOC_USP7_MATH_1	102	106	PF00917	0.693
LIG_FHA_1	135	141	PF00498	0.596
LIG_LIR_Apic_2	45	51	PF02991	0.491
LIG_PCNA_yPIPBox_3	78	89	PF02747	0.608
LIG_Pex14_2	62	66	PF04695	0.473
LIG_RPA_C_Fungi	124	136	PF08784	0.505
LIG_SH2_STAP1	25	29	PF00017	0.552
LIG_SH2_STAT3	107	110	PF00017	0.656
LIG_SH2_STAT5	107	110	PF00017	0.556
LIG_SH2_STAT5	28	31	PF00017	0.586
LIG_SH3_3	18	24	PF00018	0.622
LIG_SH3_3	51	57	PF00018	0.573
LIG_TRAF2_1	98	101	PF00917	0.619
MOD_GlcNHglycan	113	116	PF01048	0.510
MOD_GlcNHglycan	25	28	PF01048	0.520
MOD_GlcNHglycan	8	11	PF01048	0.551
MOD_GlcNHglycan	95	98	PF01048	0.673
MOD_GSK3_1	102	109	PF00069	0.602
MOD_PIKK_1	106	112	PF00454	0.674
MOD_PKA_2	110	116	PF00069	0.540
MOD_Plk_4	57	63	PF00069	0.528
TRG_ER_diArg_1	158	161	PF00400	0.526
TRG_ER_diArg_1	63	65	PF00400	0.476
TRG_Pf-PMV_PEXEL_1	161	165	PF00026	0.590


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PD34	Leptomonas seymouri	80%	100%
A0A1X0P529	Trypanosomatidae	47%	100%
A0A3Q8IQ29	Leishmania donovani	96%	100%
A0A422NU90	Trypanosoma rangeli	47%	100%
A4HN96	Leishmania braziliensis	91%	100%
A4IBW7	Leishmania infantum	96%	100%
C9ZYP2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
E9B6V7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%