Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AFN4_LEIMA

TriTrypDb:

LmjF.35.4080 , LMJLV39_350048700 , LMJSD75_350048100

Length:

1104

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AFN4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFN4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	13	17	PF00656	0.659
CLV_C14_Caspase3-7	25	29	PF00656	0.524
CLV_C14_Caspase3-7	696	700	PF00656	0.590
CLV_C14_Caspase3-7	923	927	PF00656	0.675
CLV_NRD_NRD_1	1005	1007	PF00675	0.654
CLV_NRD_NRD_1	167	169	PF00675	0.635
CLV_NRD_NRD_1	182	184	PF00675	0.594
CLV_NRD_NRD_1	186	188	PF00675	0.547
CLV_NRD_NRD_1	343	345	PF00675	0.571
CLV_NRD_NRD_1	350	352	PF00675	0.575

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGL1	Leishmania donovani	88%	100%
A4HN79	Leishmania braziliensis	62%	100%
A4IBU7	Leishmania infantum	88%	100%
E9B6T7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%

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