TPR_REGION domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MAP kinase kinase-like protein

Species:

Leishmania major

UniProt:

E9AFM5_LEIMA

TriTrypDb:

LmjF.35.4000 , LMJLV39_350047800 , LMJSD75_350047100

Length:

1343

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9AFM5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016310	phosphorylation	5	7
GO:0019538	protein metabolic process	3	7
GO:0036211	protein modification process	4	7
GO:0043170	macromolecule metabolic process	3	7
GO:0043412	macromolecule modification	4	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0071704	organic substance metabolic process	2	7
GO:1901564	organonitrogen compound metabolic process	3	7

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004672	protein kinase activity	3	7
GO:0004842	ubiquitin-protein transferase activity	4	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7
GO:0017076	purine nucleotide binding	4	7
GO:0019787	ubiquitin-like protein transferase activity	3	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140096	catalytic activity, acting on a protein	2	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	941	945	PF00656	0.369
CLV_C14_Caspase3-7	97	101	PF00656	0.567
CLV_NRD_NRD_1	1196	1198	PF00675	0.312
CLV_NRD_NRD_1	1203	1205	PF00675	0.312
CLV_NRD_NRD_1	1272	1274	PF00675	0.312
CLV_NRD_NRD_1	135	137	PF00675	0.385
CLV_NRD_NRD_1	280	282	PF00675	0.579
CLV_NRD_NRD_1	438	440	PF00675	0.478
CLV_NRD_NRD_1	446	448	PF00675	0.447
CLV_NRD_NRD_1	666	668	PF00675	0.312
CLV_NRD_NRD_1	685	687	PF00675	0.312
CLV_NRD_NRD_1	954	956	PF00675	0.350
CLV_PCSK_KEX2_1	1136	1138	PF00082	0.312
CLV_PCSK_KEX2_1	1195	1197	PF00082	0.312
CLV_PCSK_KEX2_1	1272	1274	PF00082	0.312
CLV_PCSK_KEX2_1	248	250	PF00082	0.508
CLV_PCSK_KEX2_1	280	282	PF00082	0.691
CLV_PCSK_KEX2_1	437	439	PF00082	0.485
CLV_PCSK_KEX2_1	587	589	PF00082	0.538
CLV_PCSK_KEX2_1	666	668	PF00082	0.312
CLV_PCSK_KEX2_1	684	686	PF00082	0.312
CLV_PCSK_KEX2_1	878	880	PF00082	0.388
CLV_PCSK_KEX2_1	954	956	PF00082	0.350
CLV_PCSK_PC1ET2_1	1136	1138	PF00082	0.312
CLV_PCSK_PC1ET2_1	248	250	PF00082	0.508
CLV_PCSK_PC1ET2_1	587	589	PF00082	0.409
CLV_PCSK_PC1ET2_1	878	880	PF00082	0.388
CLV_PCSK_SKI1_1	1021	1025	PF00082	0.327
CLV_PCSK_SKI1_1	1090	1094	PF00082	0.312
CLV_PCSK_SKI1_1	1197	1201	PF00082	0.312
CLV_PCSK_SKI1_1	1257	1261	PF00082	0.312
CLV_PCSK_SKI1_1	1272	1276	PF00082	0.312
CLV_PCSK_SKI1_1	1291	1295	PF00082	0.312
CLV_PCSK_SKI1_1	298	302	PF00082	0.452
CLV_PCSK_SKI1_1	321	325	PF00082	0.519
CLV_PCSK_SKI1_1	478	482	PF00082	0.484
CLV_PCSK_SKI1_1	528	532	PF00082	0.424
CLV_PCSK_SKI1_1	631	635	PF00082	0.355
CLV_PCSK_SKI1_1	706	710	PF00082	0.312
CLV_PCSK_SKI1_1	728	732	PF00082	0.388
CLV_PCSK_SKI1_1	975	979	PF00082	0.429
DEG_APCC_DBOX_1	116	124	PF00400	0.388
DEG_APCC_DBOX_1	1196	1204	PF00400	0.312
DEG_APCC_DBOX_1	723	731	PF00400	0.388
DEG_ODPH_VHL_1	1080	1093	PF01847	0.388
DEG_ODPH_VHL_1	141	154	PF01847	0.505
DEG_SIAH_1	192	200	PF03145	0.601
DEG_SPOP_SBC_1	1044	1048	PF00917	0.418
DEG_SPOP_SBC_1	395	399	PF00917	0.570
DEG_SPOP_SBC_1	499	503	PF00917	0.494
DOC_CDC14_PxL_1	1066	1074	PF14671	0.378
DOC_CKS1_1	1174	1179	PF01111	0.388
DOC_CKS1_1	165	170	PF01111	0.473
DOC_CYCLIN_RxL_1	1087	1095	PF00134	0.312
DOC_CYCLIN_RxL_1	1133	1142	PF00134	0.388
DOC_CYCLIN_RxL_1	1270	1281	PF00134	0.312
DOC_CYCLIN_yClb5_NLxxxL_5	1266	1275	PF00134	0.312
DOC_CYCLIN_yCln2_LP_2	986	992	PF00134	0.368
DOC_MAPK_DCC_7	163	171	PF00069	0.493
DOC_MAPK_gen_1	1326	1333	PF00069	0.331
DOC_MAPK_gen_1	248	259	PF00069	0.446
DOC_MAPK_gen_1	666	673	PF00069	0.312
DOC_MAPK_gen_1	684	693	PF00069	0.312
DOC_MAPK_MEF2A_6	1257	1266	PF00069	0.312
DOC_MAPK_MEF2A_6	1326	1333	PF00069	0.321
DOC_MAPK_MEF2A_6	147	154	PF00069	0.512
DOC_MAPK_MEF2A_6	25	34	PF00069	0.446
DOC_MAPK_MEF2A_6	578	586	PF00069	0.493
DOC_MAPK_MEF2A_6	867	874	PF00069	0.312
DOC_PP1_RVXF_1	704	711	PF00149	0.312
DOC_PP2B_LxvP_1	1072	1075	PF13499	0.438
DOC_PP2B_LxvP_1	1314	1317	PF13499	0.312
DOC_PP2B_LxvP_1	872	875	PF13499	0.312
DOC_PP4_FxxP_1	710	713	PF00568	0.352
DOC_USP7_MATH_1	1039	1043	PF00917	0.499
DOC_USP7_MATH_1	1049	1053	PF00917	0.576
DOC_USP7_MATH_1	1117	1121	PF00917	0.388
DOC_USP7_MATH_1	121	125	PF00917	0.388
DOC_USP7_MATH_1	131	135	PF00917	0.285
DOC_USP7_MATH_1	1334	1338	PF00917	0.388
DOC_USP7_MATH_1	173	177	PF00917	0.618
DOC_USP7_MATH_1	205	209	PF00917	0.490
DOC_USP7_MATH_1	260	264	PF00917	0.453
DOC_USP7_MATH_1	383	387	PF00917	0.647
DOC_USP7_MATH_1	395	399	PF00917	0.501
DOC_USP7_MATH_1	619	623	PF00917	0.417
DOC_USP7_MATH_1	624	628	PF00917	0.378
DOC_USP7_MATH_1	945	949	PF00917	0.381
DOC_USP7_MATH_2	345	351	PF00917	0.589
DOC_USP7_UBL2_3	1090	1094	PF12436	0.312
DOC_USP7_UBL2_3	1322	1326	PF12436	0.312
DOC_USP7_UBL2_3	156	160	PF12436	0.497
DOC_USP7_UBL2_3	248	252	PF12436	0.517
DOC_USP7_UBL2_3	320	324	PF12436	0.448
DOC_USP7_UBL2_3	92	96	PF12436	0.378
DOC_WW_Pin1_4	1033	1038	PF00397	0.538
DOC_WW_Pin1_4	1170	1175	PF00397	0.308
DOC_WW_Pin1_4	1218	1223	PF00397	0.388
DOC_WW_Pin1_4	1252	1257	PF00397	0.312
DOC_WW_Pin1_4	164	169	PF00397	0.494
DOC_WW_Pin1_4	36	41	PF00397	0.566
DOC_WW_Pin1_4	361	366	PF00397	0.710
DOC_WW_Pin1_4	391	396	PF00397	0.661
DOC_WW_Pin1_4	5	10	PF00397	0.499
DOC_WW_Pin1_4	985	990	PF00397	0.361
LIG_14-3-3_CanoR_1	1139	1146	PF00244	0.312
LIG_14-3-3_CanoR_1	1168	1177	PF00244	0.381
LIG_14-3-3_CanoR_1	1195	1203	PF00244	0.388
LIG_14-3-3_CanoR_1	189	193	PF00244	0.567
LIG_14-3-3_CanoR_1	221	227	PF00244	0.451
LIG_14-3-3_CanoR_1	389	395	PF00244	0.561
LIG_14-3-3_CanoR_1	65	73	PF00244	0.342
LIG_14-3-3_CanoR_1	778	786	PF00244	0.312
LIG_14-3-3_CanoR_1	908	915	PF00244	0.312
LIG_14-3-3_CanoR_1	954	962	PF00244	0.380
LIG_Actin_WH2_2	1080	1096	PF00022	0.312
LIG_Actin_WH2_2	1283	1299	PF00022	0.388
LIG_Actin_WH2_2	650	668	PF00022	0.388
LIG_APCC_ABBA_1	1010	1015	PF00400	0.327
LIG_BIR_III_2	201	205	PF00653	0.443
LIG_BIR_III_4	1076	1080	PF00653	0.428
LIG_BIR_III_4	457	461	PF00653	0.509
LIG_BRCT_BRCA1_1	1062	1066	PF00533	0.474
LIG_BRCT_BRCA1_1	1336	1340	PF00533	0.312
LIG_BRCT_BRCA1_1	209	213	PF00533	0.449
LIG_CaM_IQ_9	579	594	PF13499	0.388
LIG_deltaCOP1_diTrp_1	842	848	PF00928	0.340
LIG_eIF4E_1	1014	1020	PF01652	0.396
LIG_eIF4E_1	1258	1264	PF01652	0.388
LIG_FHA_1	1005	1011	PF00498	0.352
LIG_FHA_1	1279	1285	PF00498	0.291
LIG_FHA_1	1309	1315	PF00498	0.388
LIG_FHA_1	165	171	PF00498	0.478
LIG_FHA_1	192	198	PF00498	0.500
LIG_FHA_1	501	507	PF00498	0.475
LIG_FHA_1	66	72	PF00498	0.312
LIG_FHA_1	799	805	PF00498	0.291
LIG_FHA_2	1196	1202	PF00498	0.388
LIG_FHA_2	207	213	PF00498	0.528
LIG_FHA_2	223	229	PF00498	0.365
LIG_FHA_2	259	265	PF00498	0.456
LIG_FHA_2	487	493	PF00498	0.579
LIG_FHA_2	500	506	PF00498	0.434
LIG_FHA_2	532	538	PF00498	0.455
LIG_FHA_2	847	853	PF00498	0.312
LIG_FHA_2	908	914	PF00498	0.312
LIG_GBD_Chelix_1	893	901	PF00786	0.312
LIG_LIR_Apic_2	817	823	PF02991	0.312
LIG_LIR_Gen_1	1063	1074	PF02991	0.569
LIG_LIR_Gen_1	1083	1093	PF02991	0.227
LIG_LIR_Gen_1	1118	1129	PF02991	0.312
LIG_LIR_Gen_1	1152	1161	PF02991	0.312
LIG_LIR_Gen_1	1181	1190	PF02991	0.312
LIG_LIR_Gen_1	1337	1343	PF02991	0.312
LIG_LIR_Gen_1	210	220	PF02991	0.417
LIG_LIR_Gen_1	636	647	PF02991	0.334
LIG_LIR_Gen_1	659	669	PF02991	0.312
LIG_LIR_Gen_1	711	722	PF02991	0.312
LIG_LIR_Gen_1	738	746	PF02991	0.312
LIG_LIR_Gen_1	808	818	PF02991	0.243
LIG_LIR_Gen_1	85	94	PF02991	0.439
LIG_LIR_Gen_1	910	920	PF02991	0.312
LIG_LIR_Gen_1	976	986	PF02991	0.388
LIG_LIR_Nem_3	1063	1069	PF02991	0.581
LIG_LIR_Nem_3	1083	1088	PF02991	0.227
LIG_LIR_Nem_3	1118	1124	PF02991	0.312
LIG_LIR_Nem_3	1152	1156	PF02991	0.312
LIG_LIR_Nem_3	1181	1186	PF02991	0.312
LIG_LIR_Nem_3	1188	1193	PF02991	0.312
LIG_LIR_Nem_3	1245	1249	PF02991	0.312
LIG_LIR_Nem_3	1337	1343	PF02991	0.312
LIG_LIR_Nem_3	210	216	PF02991	0.420
LIG_LIR_Nem_3	565	571	PF02991	0.402
LIG_LIR_Nem_3	636	642	PF02991	0.331
LIG_LIR_Nem_3	643	647	PF02991	0.338
LIG_LIR_Nem_3	659	665	PF02991	0.312
LIG_LIR_Nem_3	711	717	PF02991	0.312
LIG_LIR_Nem_3	738	742	PF02991	0.312
LIG_LIR_Nem_3	808	814	PF02991	0.243
LIG_LIR_Nem_3	85	91	PF02991	0.357
LIG_LIR_Nem_3	910	915	PF02991	0.312
LIG_LIR_Nem_3	976	981	PF02991	0.415
LIG_MYND_1	871	875	PF01753	0.312
LIG_NRBOX	1083	1089	PF00104	0.312
LIG_NRBOX	1224	1230	PF00104	0.312
LIG_NRBOX	431	437	PF00104	0.539
LIG_NRBOX	726	732	PF00104	0.388
LIG_PCNA_PIPBox_1	1268	1277	PF02747	0.312
LIG_PCNA_yPIPBox_3	599	611	PF02747	0.434
LIG_Pex14_1	844	848	PF04695	0.340
LIG_Pex14_2	1156	1160	PF04695	0.312
LIG_Pex14_2	329	333	PF04695	0.486
LIG_Pex14_2	710	714	PF04695	0.312
LIG_PTAP_UEV_1	192	197	PF05743	0.555
LIG_PTB_Apo_2	1008	1015	PF02174	0.333
LIG_PTB_Apo_2	80	87	PF02174	0.359
LIG_PTB_Apo_2	854	861	PF02174	0.312
LIG_PTB_Phospho_1	1008	1014	PF10480	0.334
LIG_REV1ctd_RIR_1	109	117	PF16727	0.367
LIG_REV1ctd_RIR_1	327	334	PF16727	0.460
LIG_SH2_CRK	662	666	PF00017	0.312
LIG_SH2_CRK	811	815	PF00017	0.243
LIG_SH2_CRK	912	916	PF00017	0.312
LIG_SH2_GRB2like	81	84	PF00017	0.362
LIG_SH2_GRB2like	88	91	PF00017	0.362
LIG_SH2_PTP2	1183	1186	PF00017	0.312
LIG_SH2_PTP2	716	719	PF00017	0.388
LIG_SH2_SRC	1071	1074	PF00017	0.441
LIG_SH2_SRC	1127	1130	PF00017	0.243
LIG_SH2_SRC	949	952	PF00017	0.386
LIG_SH2_STAP1	1014	1018	PF00017	0.320
LIG_SH2_STAP1	233	237	PF00017	0.473
LIG_SH2_STAP1	67	71	PF00017	0.349
LIG_SH2_STAP1	912	916	PF00017	0.312
LIG_SH2_STAT3	237	240	PF00017	0.513
LIG_SH2_STAT3	66	69	PF00017	0.312
LIG_SH2_STAT5	1071	1074	PF00017	0.441
LIG_SH2_STAT5	1155	1158	PF00017	0.400
LIG_SH2_STAT5	1169	1172	PF00017	0.258
LIG_SH2_STAT5	1183	1186	PF00017	0.332
LIG_SH2_STAT5	1208	1211	PF00017	0.388
LIG_SH2_STAT5	1258	1261	PF00017	0.388
LIG_SH2_STAT5	181	184	PF00017	0.537
LIG_SH2_STAT5	67	70	PF00017	0.312
LIG_SH2_STAT5	716	719	PF00017	0.339
LIG_SH2_STAT5	755	758	PF00017	0.312
LIG_SH2_STAT5	81	84	PF00017	0.438
LIG_SH2_STAT5	88	91	PF00017	0.366
LIG_SH2_STAT5	919	922	PF00017	0.386
LIG_SH2_STAT5	949	952	PF00017	0.386
LIG_SH3_2	193	198	PF14604	0.580
LIG_SH3_3	1053	1059	PF00018	0.473
LIG_SH3_3	1067	1073	PF00018	0.360
LIG_SH3_3	1171	1177	PF00018	0.388
LIG_SH3_3	162	168	PF00018	0.478
LIG_SH3_3	190	196	PF00018	0.524
LIG_SH3_3	353	359	PF00018	0.593
LIG_SH3_3	367	373	PF00018	0.745
LIG_SH3_3	404	410	PF00018	0.720
LIG_SH3_3	865	871	PF00018	0.312
LIG_SH3_3	899	905	PF00018	0.312
LIG_SUMO_SIM_anti_2	1015	1021	PF11976	0.347
LIG_SUMO_SIM_anti_2	1223	1230	PF11976	0.312
LIG_SUMO_SIM_anti_2	988	994	PF11976	0.374
LIG_SUMO_SIM_par_1	869	876	PF11976	0.290
LIG_SUMO_SIM_par_1	961	966	PF11976	0.441
LIG_TRAF2_1	1028	1031	PF00917	0.389
LIG_TRAF2_1	323	326	PF00917	0.443
LIG_TRAF2_1	732	735	PF00917	0.388
LIG_TRFH_1	716	720	PF08558	0.312
LIG_TYR_ITIM	1012	1017	PF00017	0.300
LIG_UBA3_1	1084	1090	PF00899	0.312
LIG_UBA3_1	629	634	PF00899	0.359
LIG_UBA3_1	702	706	PF00899	0.312
MOD_CDK_SPK_2	1252	1257	PF00069	0.312
MOD_CK1_1	1042	1048	PF00069	0.509
MOD_CK1_1	1130	1136	PF00069	0.298
MOD_CK1_1	1154	1160	PF00069	0.312
MOD_CK1_1	1173	1179	PF00069	0.312
MOD_CK1_1	187	193	PF00069	0.639
MOD_CK1_1	247	253	PF00069	0.494
MOD_CK1_1	255	261	PF00069	0.434
MOD_CK1_1	263	269	PF00069	0.425
MOD_CK1_1	388	394	PF00069	0.599
MOD_CK1_1	398	404	PF00069	0.553
MOD_CK1_1	424	430	PF00069	0.573
MOD_CK1_1	651	657	PF00069	0.351
MOD_CK1_1	8	14	PF00069	0.601
MOD_CK1_1	922	928	PF00069	0.427
MOD_CK2_1	1092	1098	PF00069	0.312
MOD_CK2_1	1112	1118	PF00069	0.183
MOD_CK2_1	1182	1188	PF00069	0.310
MOD_CK2_1	1195	1201	PF00069	0.333
MOD_CK2_1	258	264	PF00069	0.453
MOD_CK2_1	486	492	PF00069	0.572
MOD_CK2_1	499	505	PF00069	0.441
MOD_CK2_1	516	522	PF00069	0.496
MOD_CK2_1	531	537	PF00069	0.454
MOD_CK2_1	729	735	PF00069	0.388
MOD_CK2_1	846	852	PF00069	0.312
MOD_GlcNHglycan	1051	1054	PF01048	0.472
MOD_GlcNHglycan	1114	1117	PF01048	0.337
MOD_GlcNHglycan	1141	1144	PF01048	0.316
MOD_GlcNHglycan	1235	1238	PF01048	0.428
MOD_GlcNHglycan	1286	1289	PF01048	0.340
MOD_GlcNHglycan	13	16	PF01048	0.511
MOD_GlcNHglycan	264	268	PF01048	0.622
MOD_GlcNHglycan	34	37	PF01048	0.491
MOD_GlcNHglycan	367	370	PF01048	0.789
MOD_GlcNHglycan	5	8	PF01048	0.501
MOD_GlcNHglycan	635	638	PF01048	0.337
MOD_GlcNHglycan	750	753	PF01048	0.312
MOD_GlcNHglycan	933	936	PF01048	0.495
MOD_GlcNHglycan	95	99	PF01048	0.466
MOD_GSK3_1	1039	1046	PF00069	0.523
MOD_GSK3_1	1060	1067	PF00069	0.439
MOD_GSK3_1	1127	1134	PF00069	0.234
MOD_GSK3_1	1178	1185	PF00069	0.290
MOD_GSK3_1	169	176	PF00069	0.672
MOD_GSK3_1	181	188	PF00069	0.504
MOD_GSK3_1	255	262	PF00069	0.450
MOD_GSK3_1	32	39	PF00069	0.487
MOD_GSK3_1	339	346	PF00069	0.570
MOD_GSK3_1	347	354	PF00069	0.557
MOD_GSK3_1	361	368	PF00069	0.586
MOD_GSK3_1	391	398	PF00069	0.542
MOD_GSK3_1	419	426	PF00069	0.725
MOD_GSK3_1	486	493	PF00069	0.580
MOD_GSK3_1	500	507	PF00069	0.476
MOD_GSK3_1	648	655	PF00069	0.348
MOD_GSK3_1	796	803	PF00069	0.312
MOD_GSK3_1	810	817	PF00069	0.312
MOD_GSK3_1	827	834	PF00069	0.273
MOD_GSK3_1	918	925	PF00069	0.397
MOD_GSK3_1	926	933	PF00069	0.462
MOD_N-GLC_1	624	629	PF02516	0.415
MOD_N-GLC_1	640	645	PF02516	0.372
MOD_N-GLC_1	805	810	PF02516	0.356
MOD_N-GLC_1	82	87	PF02516	0.369
MOD_N-GLC_1	931	936	PF02516	0.489
MOD_NEK2_1	1043	1048	PF00069	0.401
MOD_NEK2_1	1065	1070	PF00069	0.391
MOD_NEK2_1	1092	1097	PF00069	0.312
MOD_NEK2_1	1104	1109	PF00069	0.312
MOD_NEK2_1	1151	1156	PF00069	0.388
MOD_NEK2_1	1233	1238	PF00069	0.388
MOD_NEK2_1	1264	1269	PF00069	0.297
MOD_NEK2_1	206	211	PF00069	0.463
MOD_NEK2_1	305	310	PF00069	0.647
MOD_NEK2_1	32	37	PF00069	0.487
MOD_NEK2_1	42	47	PF00069	0.522
MOD_NEK2_1	421	426	PF00069	0.503
MOD_NEK2_1	463	468	PF00069	0.482
MOD_NEK2_1	531	536	PF00069	0.453
MOD_NEK2_1	653	658	PF00069	0.355
MOD_NEK2_1	79	84	PF00069	0.442
MOD_NEK2_1	798	803	PF00069	0.319
MOD_NEK2_1	827	832	PF00069	0.501
MOD_NEK2_1	846	851	PF00069	0.231
MOD_NEK2_1	893	898	PF00069	0.243
MOD_NEK2_1	920	925	PF00069	0.405
MOD_NEK2_1	94	99	PF00069	0.310
MOD_NEK2_1	970	975	PF00069	0.405
MOD_NEK2_2	131	136	PF00069	0.388
MOD_PIKK_1	1264	1270	PF00454	0.312
MOD_PIKK_1	274	280	PF00454	0.682
MOD_PIKK_1	410	416	PF00454	0.635
MOD_PIKK_1	419	425	PF00454	0.584
MOD_PIKK_1	486	492	PF00454	0.552
MOD_PIKK_1	65	71	PF00454	0.312
MOD_PK_1	674	680	PF00069	0.312
MOD_PKA_1	1195	1201	PF00069	0.388
MOD_PKA_2	1167	1173	PF00069	0.364
MOD_PKA_2	1195	1201	PF00069	0.388
MOD_PKA_2	1250	1256	PF00069	0.340
MOD_PKA_2	188	194	PF00069	0.556
MOD_PKA_2	197	203	PF00069	0.646
MOD_PKA_2	388	394	PF00069	0.561
MOD_PKA_2	723	729	PF00069	0.312
MOD_PKA_2	907	913	PF00069	0.312
MOD_PKA_2	953	959	PF00069	0.437
MOD_PKB_1	1137	1145	PF00069	0.312
MOD_Plk_1	1151	1157	PF00069	0.312
MOD_Plk_1	174	180	PF00069	0.542
MOD_Plk_1	263	269	PF00069	0.489
MOD_Plk_1	298	304	PF00069	0.455
MOD_Plk_1	640	646	PF00069	0.334
MOD_Plk_1	674	680	PF00069	0.312
MOD_Plk_1	796	802	PF00069	0.312
MOD_Plk_1	82	88	PF00069	0.356
MOD_Plk_1	861	867	PF00069	0.340
MOD_Plk_1	931	937	PF00069	0.488
MOD_Plk_2-3	1182	1188	PF00069	0.267
MOD_Plk_4	1039	1045	PF00069	0.403
MOD_Plk_4	1060	1066	PF00069	0.352
MOD_Plk_4	1092	1098	PF00069	0.312
MOD_Plk_4	1106	1112	PF00069	0.312
MOD_Plk_4	1117	1123	PF00069	0.355
MOD_Plk_4	252	258	PF00069	0.522
MOD_Plk_4	516	522	PF00069	0.503
MOD_Plk_4	735	741	PF00069	0.324
MOD_Plk_4	8	14	PF00069	0.555
MOD_Plk_4	810	816	PF00069	0.340
MOD_Plk_4	896	902	PF00069	0.316
MOD_ProDKin_1	1033	1039	PF00069	0.542
MOD_ProDKin_1	1170	1176	PF00069	0.308
MOD_ProDKin_1	1218	1224	PF00069	0.388
MOD_ProDKin_1	1252	1258	PF00069	0.312
MOD_ProDKin_1	164	170	PF00069	0.496
MOD_ProDKin_1	36	42	PF00069	0.568
MOD_ProDKin_1	361	367	PF00069	0.716
MOD_ProDKin_1	391	397	PF00069	0.660
MOD_ProDKin_1	5	11	PF00069	0.495
MOD_ProDKin_1	985	991	PF00069	0.363
MOD_SUMO_for_1	155	158	PF00179	0.511
MOD_SUMO_for_1	323	326	PF00179	0.443
MOD_SUMO_for_1	467	470	PF00179	0.524
MOD_SUMO_for_1	546	549	PF00179	0.528
MOD_SUMO_rev_2	144	149	PF00179	0.440
MOD_SUMO_rev_2	269	277	PF00179	0.555
MOD_SUMO_rev_2	539	548	PF00179	0.534
MOD_SUMO_rev_2	573	579	PF00179	0.388
TRG_DiLeu_BaEn_1	1015	1020	PF01217	0.395
TRG_DiLeu_BaEn_1	1188	1193	PF01217	0.388
TRG_DiLeu_BaEn_1	431	436	PF01217	0.480
TRG_DiLeu_BaEn_1	476	481	PF01217	0.483
TRG_DiLeu_BaEn_1	537	542	PF01217	0.457
TRG_DiLeu_BaEn_1	549	554	PF01217	0.437
TRG_DiLeu_BaEn_4	543	549	PF01217	0.533
TRG_DiLeu_BaLyEn_6	1136	1141	PF01217	0.312
TRG_DiLeu_BaLyEn_6	165	170	PF01217	0.473
TRG_DiLeu_BaLyEn_6	868	873	PF01217	0.312
TRG_DiLeu_LyEn_5	549	554	PF01217	0.516
TRG_ENDOCYTIC_2	1014	1017	PF00928	0.321
TRG_ENDOCYTIC_2	1183	1186	PF00928	0.312
TRG_ENDOCYTIC_2	662	665	PF00928	0.312
TRG_ENDOCYTIC_2	716	719	PF00928	0.312
TRG_ENDOCYTIC_2	811	814	PF00928	0.243
TRG_ENDOCYTIC_2	88	91	PF00928	0.362
TRG_ENDOCYTIC_2	912	915	PF00928	0.312
TRG_ER_diArg_1	1137	1140	PF00400	0.312
TRG_ER_diArg_1	1195	1197	PF00400	0.381
TRG_ER_diArg_1	1271	1273	PF00400	0.312
TRG_ER_diArg_1	279	281	PF00400	0.708
TRG_ER_diArg_1	436	439	PF00400	0.486
TRG_ER_diArg_1	557	560	PF00400	0.384
TRG_ER_diArg_1	665	667	PF00400	0.312
TRG_ER_diArg_1	684	686	PF00400	0.312
TRG_ER_diArg_1	953	955	PF00400	0.355
TRG_NES_CRM1_1	1224	1238	PF08389	0.312
TRG_NES_CRM1_1	431	444	PF08389	0.557
TRG_NES_CRM1_1	561	574	PF08389	0.388
TRG_NES_CRM1_1	891	904	PF08389	0.388
TRG_Pf-PMV_PEXEL_1	1257	1261	PF00026	0.312
TRG_Pf-PMV_PEXEL_1	478	483	PF00026	0.484
TRG_Pf-PMV_PEXEL_1	552	556	PF00026	0.622
TRG_Pf-PMV_PEXEL_1	975	979	PF00026	0.429

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3D7	Leptomonas seymouri	67%	94%
A0A3S7X9U1	Leishmania donovani	97%	100%
A4HN70	Leishmania braziliensis	85%	95%
A4IBT8	Leishmania infantum	97%	100%
E9B6S8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%