4E-interacting_protein

4E-interacting protein, putative

Leishmania major

796

Source | Evidence on protein | Close homologs |
---|---|---|

Cuervo et al. | no | yes: 0 |

Hassani et al. | no | yes: 0 |

Forrest at al. (metacyclic) | no | yes: 0 |

Forrest at al. (procyclic) | no | yes: 0 |

Silverman et al. | no | yes: 0 |

Pissara et al. | no | yes: 0 |

Source | Evidence on protein | Close homologs |
---|---|---|

Pires et al. | no | yes: 0 |

Source | Evidence on protein | Close homologs |
---|---|---|

Silverman et al. | no | yes: 0 |

Source | Evidence on protein | Close homologs |
---|---|---|

Jamdhade et al. | no | yes: 0 |

Source | Evidence on protein | Close homologs |
---|---|---|

DeepLoc | ||

SignalP6 | no | yes: 0, no: 6 |

NetGPI | no | yes: 0, no: 6 |

Term | Name | Level | Count |
---|---|---|---|

GO:0005737 | cytoplasm | 2 | 2 |

GO:0110165 | cellular anatomical entity | 1 | 2 |

E9AFM3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Term | Name | Level | Count |
---|---|---|---|

GO:0006417 | regulation of translation | 6 | 2 |

GO:0009889 | regulation of biosynthetic process | 4 | 2 |

GO:0010468 | regulation of gene expression | 5 | 2 |

GO:0010556 | regulation of macromolecule biosynthetic process | 5 | 2 |

GO:0010608 | post-transcriptional regulation of gene expression | 6 | 2 |

GO:0019222 | regulation of metabolic process | 3 | 2 |

GO:0031323 | regulation of cellular metabolic process | 4 | 2 |

GO:0031326 | regulation of cellular biosynthetic process | 5 | 2 |

GO:0034248 | regulation of amide metabolic process | 5 | 2 |

GO:0050789 | regulation of biological process | 2 | 2 |

GO:0050794 | regulation of cellular process | 3 | 2 |

GO:0051171 | regulation of nitrogen compound metabolic process | 4 | 2 |

GO:0051246 | regulation of protein metabolic process | 5 | 2 |

GO:0060255 | regulation of macromolecule metabolic process | 4 | 2 |

GO:0065007 | biological regulation | 1 | 2 |

GO:0080090 | regulation of primary metabolic process | 4 | 2 |

GO:2000112 | obsolete regulation of cellular macromolecule biosynthetic process | 6 | 2 |

Term | Name | Level | Count |
---|---|---|---|

GO:0045182 | translation regulator activity | 1 | 2 |

Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|

CLV_C14_Caspase3-7 | 207 | 211 | PF00656 | 0.551 |

CLV_NRD_NRD_1 | 119 | 121 | PF00675 | 0.621 |

CLV_NRD_NRD_1 | 191 | 193 | PF00675 | 0.483 |

CLV_NRD_NRD_1 | 30 | 32 | PF00675 | 0.552 |

CLV_NRD_NRD_1 | 47 | 49 | PF00675 | 0.608 |

CLV_NRD_NRD_1 | 747 | 749 | PF00675 | 0.559 |

CLV_PCSK_KEX2_1 | 119 | 121 | PF00082 | 0.610 |

CLV_PCSK_KEX2_1 | 181 | 183 | PF00082 | 0.469 |

CLV_PCSK_KEX2_1 | 46 | 48 | PF00082 | 0.621 |

CLV_PCSK_KEX2_1 | 747 | 749 | PF00082 | 0.559 |

CLV_PCSK_PC1ET2_1 | 181 | 183 | PF00082 | 0.469 |

CLV_PCSK_PC1ET2_1 | 46 | 48 | PF00082 | 0.620 |

CLV_PCSK_SKI1_1 | 15 | 19 | PF00082 | 0.487 |

CLV_PCSK_SKI1_1 | 198 | 202 | PF00082 | 0.478 |

CLV_PCSK_SKI1_1 | 503 | 507 | PF00082 | 0.599 |

CLV_PCSK_SKI1_1 | 548 | 552 | PF00082 | 0.614 |

CLV_Separin_Metazoa | 12 | 16 | PF03568 | 0.509 |

CLV_Separin_Metazoa | 28 | 32 | PF03568 | 0.406 |

DEG_APCC_DBOX_1 | 9 | 17 | PF00400 | 0.458 |

DEG_COP1_1 | 481 | 491 | PF00400 | 0.660 |

DEG_SCF_FBW7_1 | 296 | 303 | PF00400 | 0.609 |

DEG_SCF_FBW7_1 | 451 | 458 | PF00400 | 0.634 |

DEG_SIAH_1 | 291 | 299 | PF03145 | 0.626 |

DEG_SPOP_SBC_1 | 100 | 104 | PF00917 | 0.679 |

DEG_SPOP_SBC_1 | 368 | 372 | PF00917 | 0.615 |

DOC_CKS1_1 | 297 | 302 | PF01111 | 0.606 |

DOC_CKS1_1 | 42 | 47 | PF01111 | 0.541 |

DOC_CKS1_1 | 452 | 457 | PF01111 | 0.667 |

DOC_CYCLIN_yClb3_PxF_3 | 559 | 565 | PF00134 | 0.657 |

DOC_CYCLIN_yClb5_NLxxxL_5 | 193 | 201 | PF00134 | 0.491 |

DOC_CYCLIN_yCln2_LP_2 | 715 | 721 | PF00134 | 0.570 |

DOC_MAPK_gen_1 | 31 | 38 | PF00069 | 0.597 |

DOC_PP2B_LxvP_1 | 629 | 632 | PF13499 | 0.622 |

DOC_PP2B_LxvP_1 | 715 | 718 | PF13499 | 0.582 |

DOC_PP4_FxxP_1 | 148 | 151 | PF00568 | 0.538 |

DOC_PP4_FxxP_1 | 277 | 280 | PF00568 | 0.612 |

DOC_PP4_FxxP_1 | 401 | 404 | PF00568 | 0.604 |

DOC_PP4_FxxP_1 | 565 | 568 | PF00568 | 0.657 |

DOC_PP4_FxxP_1 | 578 | 581 | PF00568 | 0.566 |

DOC_PP4_FxxP_1 | 728 | 731 | PF00568 | 0.491 |

DOC_PP4_FxxP_1 | 746 | 749 | PF00568 | 0.426 |

DOC_USP7_MATH_1 | 100 | 104 | PF00917 | 0.827 |

DOC_USP7_MATH_1 | 269 | 273 | PF00917 | 0.633 |

DOC_USP7_MATH_1 | 280 | 284 | PF00917 | 0.575 |

DOC_USP7_MATH_1 | 292 | 296 | PF00917 | 0.733 |

DOC_USP7_MATH_1 | 300 | 304 | PF00917 | 0.532 |

DOC_USP7_MATH_1 | 312 | 316 | PF00917 | 0.583 |

DOC_USP7_MATH_1 | 346 | 350 | PF00917 | 0.762 |

DOC_USP7_MATH_1 | 369 | 373 | PF00917 | 0.656 |

DOC_USP7_MATH_1 | 383 | 387 | PF00917 | 0.551 |

DOC_USP7_MATH_1 | 393 | 397 | PF00917 | 0.714 |

DOC_USP7_MATH_1 | 415 | 419 | PF00917 | 0.664 |

DOC_USP7_MATH_1 | 459 | 463 | PF00917 | 0.763 |

DOC_USP7_MATH_1 | 479 | 483 | PF00917 | 0.556 |

DOC_USP7_MATH_1 | 579 | 583 | PF00917 | 0.744 |

DOC_USP7_MATH_1 | 588 | 592 | PF00917 | 0.623 |

DOC_USP7_MATH_1 | 635 | 639 | PF00917 | 0.640 |

DOC_USP7_MATH_1 | 641 | 645 | PF00917 | 0.637 |

DOC_WW_Pin1_4 | 102 | 107 | PF00397 | 0.623 |

DOC_WW_Pin1_4 | 262 | 267 | PF00397 | 0.653 |

DOC_WW_Pin1_4 | 288 | 293 | PF00397 | 0.640 |

DOC_WW_Pin1_4 | 296 | 301 | PF00397 | 0.586 |

DOC_WW_Pin1_4 | 344 | 349 | PF00397 | 0.661 |

DOC_WW_Pin1_4 | 407 | 412 | PF00397 | 0.602 |

DOC_WW_Pin1_4 | 41 | 46 | PF00397 | 0.550 |

DOC_WW_Pin1_4 | 451 | 456 | PF00397 | 0.663 |

DOC_WW_Pin1_4 | 558 | 563 | PF00397 | 0.652 |

DOC_WW_Pin1_4 | 581 | 586 | PF00397 | 0.659 |

DOC_WW_Pin1_4 | 597 | 602 | PF00397 | 0.531 |

DOC_WW_Pin1_4 | 664 | 669 | PF00397 | 0.593 |

DOC_WW_Pin1_4 | 686 | 691 | PF00397 | 0.667 |

LIG_14-3-3_CanoR_1 | 15 | 20 | PF00244 | 0.527 |

LIG_14-3-3_CanoR_1 | 244 | 251 | PF00244 | 0.630 |

LIG_AP2alpha_1 | 59 | 63 | PF02296 | 0.538 |

LIG_APCC_ABBAyCdc20_2 | 55 | 61 | PF00400 | 0.544 |

LIG_BIR_III_2 | 345 | 349 | PF00653 | 0.633 |

LIG_BRCT_BRCA1_1 | 242 | 246 | PF00533 | 0.556 |

LIG_EH_1 | 776 | 780 | PF12763 | 0.614 |

LIG_eIF4E_1 | 8 | 14 | PF01652 | 0.453 |

LIG_EVH1_1 | 629 | 633 | PF00568 | 0.622 |

LIG_FHA_1 | 218 | 224 | PF00498 | 0.509 |

LIG_FHA_1 | 526 | 532 | PF00498 | 0.630 |

LIG_FHA_1 | 692 | 698 | PF00498 | 0.665 |

LIG_FHA_2 | 162 | 168 | PF00498 | 0.531 |

LIG_FHA_2 | 229 | 235 | PF00498 | 0.585 |

LIG_FHA_2 | 252 | 258 | PF00498 | 0.631 |

LIG_FHA_2 | 530 | 536 | PF00498 | 0.585 |

LIG_FHA_2 | 7 | 13 | PF00498 | 0.460 |

LIG_LIR_Apic_2 | 146 | 151 | PF02991 | 0.548 |

LIG_LIR_Apic_2 | 274 | 280 | PF02991 | 0.614 |

LIG_LIR_Apic_2 | 400 | 404 | PF02991 | 0.603 |

LIG_LIR_Gen_1 | 143 | 151 | PF02991 | 0.608 |

LIG_LIR_Gen_1 | 667 | 676 | PF02991 | 0.580 |

LIG_LIR_Nem_3 | 143 | 148 | PF02991 | 0.727 |

LIG_MLH1_MIPbox_1 | 242 | 246 | PF16413 | 0.556 |

LIG_MYND_1 | 695 | 699 | PF01753 | 0.661 |

LIG_NRBOX | 496 | 502 | PF00104 | 0.513 |

LIG_NRP_CendR_1 | 795 | 796 | PF00754 | 0.584 |

LIG_Pex14_2 | 59 | 63 | PF04695 | 0.559 |

LIG_SH2_STAP1 | 145 | 149 | PF00017 | 0.555 |

LIG_SH2_STAT5 | 727 | 730 | PF00017 | 0.520 |

LIG_SH2_STAT5 | 8 | 11 | PF00017 | 0.455 |

LIG_SH3_2 | 348 | 353 | PF14604 | 0.552 |

LIG_SH3_3 | 261 | 267 | PF00018 | 0.644 |

LIG_SH3_3 | 345 | 351 | PF00018 | 0.637 |

LIG_SH3_3 | 35 | 41 | PF00018 | 0.583 |

LIG_SH3_3 | 400 | 406 | PF00018 | 0.659 |

LIG_SH3_3 | 408 | 414 | PF00018 | 0.581 |

LIG_SH3_3 | 416 | 422 | PF00018 | 0.547 |

LIG_SH3_3 | 445 | 451 | PF00018 | 0.669 |

LIG_SH3_3 | 453 | 459 | PF00018 | 0.622 |

LIG_SH3_3 | 463 | 469 | PF00018 | 0.648 |

LIG_SH3_3 | 509 | 515 | PF00018 | 0.618 |

LIG_SH3_3 | 556 | 562 | PF00018 | 0.658 |

LIG_SH3_3 | 565 | 571 | PF00018 | 0.573 |

LIG_SH3_3 | 582 | 588 | PF00018 | 0.523 |

LIG_SH3_3 | 616 | 622 | PF00018 | 0.662 |

LIG_SH3_3 | 625 | 631 | PF00018 | 0.585 |

LIG_SH3_3 | 670 | 676 | PF00018 | 0.651 |

LIG_SH3_3 | 693 | 699 | PF00018 | 0.665 |

LIG_SH3_3 | 772 | 778 | PF00018 | 0.628 |

LIG_SUMO_SIM_anti_2 | 496 | 501 | PF11976 | 0.524 |

LIG_SUMO_SIM_par_1 | 34 | 40 | PF11976 | 0.573 |

LIG_TRAF2_1 | 164 | 167 | PF00917 | 0.530 |

LIG_TRAF2_1 | 9 | 12 | PF00917 | 0.508 |

LIG_WW_3 | 569 | 573 | PF00397 | 0.534 |

MOD_CDK_SPK_2 | 41 | 46 | PF00069 | 0.532 |

MOD_CDK_SPxK_1 | 41 | 47 | PF00069 | 0.539 |

MOD_CDK_SPxxK_3 | 41 | 48 | PF00069 | 0.531 |

MOD_CK1_1 | 102 | 108 | PF00069 | 0.610 |

MOD_CK1_1 | 134 | 140 | PF00069 | 0.528 |

MOD_CK1_1 | 3 | 9 | PF00069 | 0.444 |

MOD_CK1_1 | 315 | 321 | PF00069 | 0.762 |

MOD_CK1_1 | 328 | 334 | PF00069 | 0.484 |

MOD_CK1_1 | 359 | 365 | PF00069 | 0.719 |

MOD_CK1_1 | 386 | 392 | PF00069 | 0.665 |

MOD_CK1_1 | 464 | 470 | PF00069 | 0.611 |

MOD_CK1_1 | 481 | 487 | PF00069 | 0.647 |

MOD_CK1_1 | 57 | 63 | PF00069 | 0.663 |

MOD_CK1_1 | 591 | 597 | PF00069 | 0.630 |

MOD_CK1_1 | 64 | 70 | PF00069 | 0.595 |

MOD_CK1_1 | 686 | 692 | PF00069 | 0.581 |

MOD_CK2_1 | 161 | 167 | PF00069 | 0.539 |

MOD_CK2_1 | 251 | 257 | PF00069 | 0.625 |

MOD_CK2_1 | 529 | 535 | PF00069 | 0.595 |

MOD_CK2_1 | 6 | 12 | PF00069 | 0.542 |

MOD_GlcNHglycan | 109 | 112 | PF01048 | 0.585 |

MOD_GlcNHglycan | 142 | 145 | PF01048 | 0.593 |

MOD_GlcNHglycan | 175 | 178 | PF01048 | 0.434 |

MOD_GlcNHglycan | 20 | 23 | PF01048 | 0.497 |

MOD_GlcNHglycan | 246 | 249 | PF01048 | 0.579 |

MOD_GlcNHglycan | 254 | 257 | PF01048 | 0.620 |

MOD_GlcNHglycan | 302 | 305 | PF01048 | 0.609 |

MOD_GlcNHglycan | 330 | 333 | PF01048 | 0.577 |

MOD_GlcNHglycan | 385 | 388 | PF01048 | 0.686 |

MOD_GlcNHglycan | 393 | 396 | PF01048 | 0.604 |

MOD_GlcNHglycan | 443 | 446 | PF01048 | 0.669 |

MOD_GlcNHglycan | 481 | 484 | PF01048 | 0.643 |

MOD_GlcNHglycan | 492 | 495 | PF01048 | 0.620 |

MOD_GlcNHglycan | 509 | 512 | PF01048 | 0.537 |

MOD_GlcNHglycan | 520 | 523 | PF01048 | 0.756 |

MOD_GlcNHglycan | 594 | 597 | PF01048 | 0.629 |

MOD_GlcNHglycan | 79 | 82 | PF01048 | 0.790 |

MOD_GlcNHglycan | 87 | 90 | PF01048 | 0.662 |

MOD_GSK3_1 | 132 | 139 | PF00069 | 0.633 |

MOD_GSK3_1 | 240 | 247 | PF00069 | 0.600 |

MOD_GSK3_1 | 258 | 265 | PF00069 | 0.770 |

MOD_GSK3_1 | 269 | 276 | PF00069 | 0.648 |

MOD_GSK3_1 | 288 | 295 | PF00069 | 0.668 |

MOD_GSK3_1 | 296 | 303 | PF00069 | 0.574 |

MOD_GSK3_1 | 311 | 318 | PF00069 | 0.603 |

MOD_GSK3_1 | 321 | 328 | PF00069 | 0.647 |

MOD_GSK3_1 | 333 | 340 | PF00069 | 0.607 |

MOD_GSK3_1 | 359 | 366 | PF00069 | 0.676 |

MOD_GSK3_1 | 369 | 376 | PF00069 | 0.580 |

MOD_GSK3_1 | 383 | 390 | PF00069 | 0.607 |

MOD_GSK3_1 | 393 | 400 | PF00069 | 0.562 |

MOD_GSK3_1 | 426 | 433 | PF00069 | 0.736 |

MOD_GSK3_1 | 436 | 443 | PF00069 | 0.596 |

MOD_GSK3_1 | 451 | 458 | PF00069 | 0.603 |

MOD_GSK3_1 | 478 | 485 | PF00069 | 0.676 |

MOD_GSK3_1 | 486 | 493 | PF00069 | 0.731 |

MOD_GSK3_1 | 503 | 510 | PF00069 | 0.595 |

MOD_GSK3_1 | 514 | 521 | PF00069 | 0.574 |

MOD_GSK3_1 | 525 | 532 | PF00069 | 0.755 |

MOD_GSK3_1 | 554 | 561 | PF00069 | 0.660 |

MOD_GSK3_1 | 57 | 64 | PF00069 | 0.714 |

MOD_GSK3_1 | 588 | 595 | PF00069 | 0.634 |

MOD_GSK3_1 | 641 | 648 | PF00069 | 0.657 |

MOD_N-GLC_1 | 383 | 388 | PF02516 | 0.580 |

MOD_N-GLC_1 | 61 | 66 | PF02516 | 0.594 |

MOD_N-GLC_1 | 686 | 691 | PF02516 | 0.667 |

MOD_NEK2_1 | 173 | 178 | PF00069 | 0.480 |

MOD_NEK2_1 | 322 | 327 | PF00069 | 0.585 |

MOD_NEK2_1 | 333 | 338 | PF00069 | 0.597 |

MOD_NEK2_1 | 507 | 512 | PF00069 | 0.628 |

MOD_NEK2_1 | 54 | 59 | PF00069 | 0.728 |

MOD_NEK2_1 | 63 | 68 | PF00069 | 0.585 |

MOD_NEK2_2 | 312 | 317 | PF00069 | 0.637 |

MOD_NEK2_2 | 749 | 754 | PF00069 | 0.555 |

MOD_PIKK_1 | 259 | 265 | PF00454 | 0.543 |

MOD_PIKK_1 | 302 | 308 | PF00454 | 0.624 |

MOD_PIKK_1 | 356 | 362 | PF00454 | 0.734 |

MOD_PIKK_1 | 459 | 465 | PF00454 | 0.711 |

MOD_PIKK_1 | 525 | 531 | PF00454 | 0.692 |

MOD_PIKK_1 | 635 | 641 | PF00454 | 0.641 |

MOD_PIKK_1 | 645 | 651 | PF00454 | 0.601 |

MOD_PKA_2 | 140 | 146 | PF00069 | 0.537 |

MOD_PKA_2 | 173 | 179 | PF00069 | 0.458 |

MOD_PKA_2 | 479 | 485 | PF00069 | 0.656 |

MOD_PKB_1 | 242 | 250 | PF00069 | 0.568 |

MOD_Plk_2-3 | 217 | 223 | PF00069 | 0.572 |

MOD_Plk_4 | 292 | 298 | PF00069 | 0.667 |

MOD_Plk_4 | 415 | 421 | PF00069 | 0.677 |

MOD_Plk_4 | 503 | 509 | PF00069 | 0.606 |

MOD_Plk_4 | 535 | 541 | PF00069 | 0.511 |

MOD_Plk_4 | 54 | 60 | PF00069 | 0.671 |

MOD_Plk_4 | 749 | 755 | PF00069 | 0.558 |

MOD_ProDKin_1 | 102 | 108 | PF00069 | 0.625 |

MOD_ProDKin_1 | 262 | 268 | PF00069 | 0.650 |

MOD_ProDKin_1 | 288 | 294 | PF00069 | 0.641 |

MOD_ProDKin_1 | 296 | 302 | PF00069 | 0.587 |

MOD_ProDKin_1 | 344 | 350 | PF00069 | 0.661 |

MOD_ProDKin_1 | 407 | 413 | PF00069 | 0.604 |

MOD_ProDKin_1 | 41 | 47 | PF00069 | 0.553 |

MOD_ProDKin_1 | 451 | 457 | PF00069 | 0.668 |

MOD_ProDKin_1 | 558 | 564 | PF00069 | 0.656 |

MOD_ProDKin_1 | 581 | 587 | PF00069 | 0.661 |

MOD_ProDKin_1 | 597 | 603 | PF00069 | 0.533 |

MOD_ProDKin_1 | 664 | 670 | PF00069 | 0.592 |

MOD_ProDKin_1 | 686 | 692 | PF00069 | 0.667 |

MOD_SUMO_for_1 | 204 | 207 | PF00179 | 0.550 |

TRG_DiLeu_BaEn_1 | 222 | 227 | PF01217 | 0.537 |

TRG_DiLeu_BaLyEn_6 | 572 | 577 | PF01217 | 0.612 |

TRG_DiLeu_LyEn_5 | 222 | 227 | PF01217 | 0.537 |

TRG_ENDOCYTIC_2 | 145 | 148 | PF00928 | 0.620 |

TRG_ER_diArg_1 | 241 | 244 | PF00400 | 0.552 |

TRG_ER_diArg_1 | 746 | 748 | PF00400 | 0.524 |

TRG_NES_CRM1_1 | 24 | 37 | PF08389 | 0.561 |

TRG_NLS_MonoExtC_3 | 179 | 185 | PF00514 | 0.466 |

Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|

A0A0N1HU08 | Leptomonas seymouri | 41% | 100% |

A0A3S7X9R7 | Leishmania donovani | 90% | 100% |

A4HN68 | Leishmania braziliensis | 72% | 100% |

A4IBT6 | Leishmania infantum | 90% | 100% |

E9B6S6 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 89% | 100% |