Putative 60S ribosomal protein L27A/L29

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L27A/L29, putative

Species:

Leishmania major

UniProt:

E9AFK0_LEIMA

TriTrypDb:

LmjF.35.3760 , LMJLV39_350045200 , LMJSD75_350044800

Length:

145

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 7

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 14

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Show entries

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0005737	cytoplasm	2	2
GO:0015934	large ribosomal subunit	4	10
GO:0022625	cytosolic large ribosomal subunit	5	2
GO:0032991	protein-containing complex	1	10
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0044391	ribosomal subunit	3	10

Previous1 2Next

Expansion

Sequence features

E9AFK0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFK0

PDB structure(s): 6az3_L

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	10
GO:0006518	peptide metabolic process	4	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0009058	biosynthetic process	2	10
GO:0009059	macromolecule biosynthetic process	4	10
GO:0009987	cellular process	1	10
GO:0019538	protein metabolic process	3	10
GO:0034641	cellular nitrogen compound metabolic process	3	10
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	10

Previous1 2 3Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	10
GO:0005198	structural molecule activity	1	10

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	134	136	PF00675	0.380
CLV_NRD_NRD_1	25	27	PF00675	0.563
CLV_NRD_NRD_1	62	64	PF00675	0.530
CLV_PCSK_SKI1_1	89	93	PF00082	0.465
DOC_MAPK_DCC_7	92	101	PF00069	0.383
DOC_MAPK_gen_1	132	143	PF00069	0.380
DOC_MAPK_gen_1	89	98	PF00069	0.405
DOC_MAPK_MEF2A_6	92	101	PF00069	0.380
DOC_PP1_RVXF_1	40	46	PF00149	0.380
DOC_USP7_UBL2_3	128	132	PF12436	0.380

Previous1 2 3 4Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4J103	Bodo saltans	81%	100%
A0A1D8PSC5	Candida albicans (strain SC5314 / ATCC MYA-2876)	54%	97%
A0A1X0NDQ3	Trypanosomatidae	82%	100%
A0A3Q8IGI9	Leishmania donovani	99%	100%
A0A3R7KFD5	Trypanosoma rangeli	83%	100%
A1RT57	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	40%	93%
A1RWR4	Thermofilum pendens (strain DSM 2475 / Hrk 5)	37%	96%
A2BME1	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	41%	96%
A3DNC9	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	32%	95%
A3MUZ1	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	37%	93%

Previous1 2 3 4 5 6Next