Fusaric acid resistance protein-like-domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Fusaric acid resistance protein-like, putative

Species:

Leishmania major

UniProt:

E9AFI1_LEIMA

TriTrypDb:

LmjF.35.3570 , LMJLV39_350043100 , LMJSD75_350042600

Length:

1190

Annotations

LeishMANIAdb annotations

This protein has a very unusual architecture, as it contains massive helical bundle domains outside the membrane. It is related to bacterial Fusaric acid resistance protein FusC, by a duplication of the latter. The distant bacterial relatives are thought to be para-hydroxybenzoic acid efflux pumps. The family has massively expanded in Kinetoplastids.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005886	plasma membrane	3	2
GO:0016020	membrane	2	15
GO:0110165	cellular anatomical entity	1	15

Expansion

Sequence features

E9AFI1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFI1

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	3
GO:0009987	cellular process	1	2
GO:0051179	localization	1	3
GO:0051234	establishment of localization	2	3
GO:0055085	transmembrane transport	2	2
GO:0006811	monoatomic ion transport	4	1
GO:0006820	monoatomic anion transport	5	1
GO:0006835	dicarboxylic acid transport	7	1
GO:0015711	organic anion transport	5	1
GO:0015740	C4-dicarboxylate transport	8	1
GO:0015743	malate transport	6	1
GO:0015849	organic acid transport	5	1
GO:0046942	carboxylic acid transport	6	1
GO:0071702	organic substance transport	4	1

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	2
GO:0022857	transmembrane transporter activity	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	515	519	PF00656	0.575
CLV_C14_Caspase3-7	988	992	PF00656	0.488
CLV_NRD_NRD_1	1122	1124	PF00675	0.688
CLV_NRD_NRD_1	180	182	PF00675	0.473
CLV_NRD_NRD_1	300	302	PF00675	0.260
CLV_NRD_NRD_1	495	497	PF00675	0.451
CLV_NRD_NRD_1	524	526	PF00675	0.343
CLV_NRD_NRD_1	603	605	PF00675	0.362
CLV_NRD_NRD_1	851	853	PF00675	0.399
CLV_NRD_NRD_1	914	916	PF00675	0.420
CLV_NRD_NRD_1	969	971	PF00675	0.324
CLV_PCSK_FUR_1	601	605	PF00082	0.307
CLV_PCSK_FUR_1	760	764	PF00082	0.358
CLV_PCSK_KEX2_1	1122	1124	PF00082	0.741
CLV_PCSK_KEX2_1	180	182	PF00082	0.513
CLV_PCSK_KEX2_1	241	243	PF00082	0.406
CLV_PCSK_KEX2_1	300	302	PF00082	0.274
CLV_PCSK_KEX2_1	352	354	PF00082	0.399
CLV_PCSK_KEX2_1	524	526	PF00082	0.345
CLV_PCSK_KEX2_1	603	605	PF00082	0.372
CLV_PCSK_KEX2_1	762	764	PF00082	0.337
CLV_PCSK_KEX2_1	851	853	PF00082	0.399
CLV_PCSK_KEX2_1	914	916	PF00082	0.401
CLV_PCSK_PC1ET2_1	241	243	PF00082	0.406
CLV_PCSK_PC1ET2_1	352	354	PF00082	0.399
CLV_PCSK_PC1ET2_1	762	764	PF00082	0.337
CLV_PCSK_PC7_1	176	182	PF00082	0.531
CLV_PCSK_SKI1_1	1023	1027	PF00082	0.698
CLV_PCSK_SKI1_1	104	108	PF00082	0.570
CLV_PCSK_SKI1_1	1079	1083	PF00082	0.772
CLV_PCSK_SKI1_1	393	397	PF00082	0.344
CLV_PCSK_SKI1_1	428	432	PF00082	0.304
CLV_PCSK_SKI1_1	496	500	PF00082	0.416
CLV_PCSK_SKI1_1	525	529	PF00082	0.348
CLV_PCSK_SKI1_1	595	599	PF00082	0.374
CLV_PCSK_SKI1_1	851	855	PF00082	0.365
CLV_PCSK_SKI1_1	955	959	PF00082	0.418
CLV_Separin_Metazoa	848	852	PF03568	0.558
DEG_APCC_DBOX_1	438	446	PF00400	0.522
DEG_APCC_DBOX_1	495	503	PF00400	0.618
DEG_APCC_KENBOX_2	587	591	PF00400	0.649
DEG_SCF_FBW7_1	1092	1098	PF00400	0.523
DEG_SPOP_SBC_1	48	52	PF00917	0.702
DOC_AGCK_PIF_2	412	417	PF00069	0.577
DOC_CKS1_1	1092	1097	PF01111	0.500
DOC_CKS1_1	12	17	PF01111	0.708
DOC_CKS1_1	75	80	PF01111	0.686
DOC_CYCLIN_RxL_1	492	504	PF00134	0.606
DOC_CYCLIN_RxL_1	592	600	PF00134	0.611
DOC_CYCLIN_yClb3_PxF_3	752	760	PF00134	0.232
DOC_CYCLIN_yCln2_LP_2	418	424	PF00134	0.578
DOC_CYCLIN_yCln2_LP_2	749	755	PF00134	0.381
DOC_MAPK_DCC_7	62	70	PF00069	0.739
DOC_MAPK_FxFP_2	1146	1149	PF00069	0.453
DOC_MAPK_FxFP_2	345	348	PF00069	0.452
DOC_MAPK_gen_1	103	111	PF00069	0.667
DOC_MAPK_gen_1	300	307	PF00069	0.459
DOC_MAPK_gen_1	494	502	PF00069	0.623
DOC_MAPK_gen_1	699	709	PF00069	0.493
DOC_MAPK_gen_1	854	862	PF00069	0.639
DOC_MAPK_gen_1	864	872	PF00069	0.691
DOC_MAPK_gen_1	970	978	PF00069	0.480
DOC_MAPK_MEF2A_6	204	212	PF00069	0.390
DOC_MAPK_MEF2A_6	614	623	PF00069	0.378
DOC_MAPK_MEF2A_6	62	70	PF00069	0.683
DOC_MAPK_MEF2A_6	970	978	PF00069	0.489
DOC_MAPK_NFAT4_5	971	979	PF00069	0.511
DOC_MAPK_RevD_3	338	353	PF00069	0.349
DOC_MAPK_RevD_3	748	763	PF00069	0.369
DOC_PP1_RVXF_1	426	433	PF00149	0.598
DOC_PP2B_LxvP_1	175	178	PF13499	0.707
DOC_PP2B_LxvP_1	190	193	PF13499	0.672
DOC_PP2B_LxvP_1	63	66	PF13499	0.689
DOC_PP2B_LxvP_1	70	73	PF13499	0.723
DOC_PP2B_LxvP_1	749	752	PF13499	0.424
DOC_PP4_FxxP_1	1146	1149	PF00568	0.365
DOC_PP4_FxxP_1	149	152	PF00568	0.523
DOC_PP4_FxxP_1	226	229	PF00568	0.445
DOC_PP4_FxxP_1	260	263	PF00568	0.368
DOC_PP4_FxxP_1	345	348	PF00568	0.452
DOC_PP4_FxxP_1	377	380	PF00568	0.586
DOC_PP4_FxxP_1	636	639	PF00568	0.355
DOC_PP4_FxxP_1	781	784	PF00568	0.570
DOC_USP7_MATH_1	1029	1033	PF00917	0.602
DOC_USP7_MATH_1	105	109	PF00917	0.747
DOC_USP7_MATH_1	1070	1074	PF00917	0.492
DOC_USP7_MATH_1	1149	1153	PF00917	0.405
DOC_USP7_MATH_1	39	43	PF00917	0.781
DOC_USP7_MATH_1	454	458	PF00917	0.634
DOC_USP7_MATH_1	48	52	PF00917	0.780
DOC_USP7_MATH_1	613	617	PF00917	0.333
DOC_USP7_MATH_1	643	647	PF00917	0.296
DOC_USP7_MATH_1	717	721	PF00917	0.300
DOC_USP7_MATH_1	761	765	PF00917	0.597
DOC_USP7_MATH_1	875	879	PF00917	0.533
DOC_USP7_MATH_1	989	993	PF00917	0.470
DOC_USP7_MATH_2	15	21	PF00917	0.674
DOC_USP7_UBL2_3	857	861	PF12436	0.641
DOC_WW_Pin1_4	1044	1049	PF00397	0.551
DOC_WW_Pin1_4	1050	1055	PF00397	0.534
DOC_WW_Pin1_4	1091	1096	PF00397	0.564
DOC_WW_Pin1_4	11	16	PF00397	0.707
DOC_WW_Pin1_4	113	118	PF00397	0.738
DOC_WW_Pin1_4	1135	1140	PF00397	0.513
DOC_WW_Pin1_4	221	226	PF00397	0.425
DOC_WW_Pin1_4	376	381	PF00397	0.584
DOC_WW_Pin1_4	61	66	PF00397	0.639
DOC_WW_Pin1_4	677	682	PF00397	0.537
DOC_WW_Pin1_4	74	79	PF00397	0.654
DOC_WW_Pin1_4	751	756	PF00397	0.349
DOC_WW_Pin1_4	98	103	PF00397	0.680
LIG_14-3-3_CanoR_1	1020	1026	PF00244	0.409
LIG_14-3-3_CanoR_1	1062	1068	PF00244	0.577
LIG_14-3-3_CanoR_1	1079	1084	PF00244	0.545
LIG_14-3-3_CanoR_1	1113	1118	PF00244	0.463
LIG_14-3-3_CanoR_1	134	139	PF00244	0.635
LIG_14-3-3_CanoR_1	181	187	PF00244	0.672
LIG_14-3-3_CanoR_1	204	212	PF00244	0.324
LIG_14-3-3_CanoR_1	364	374	PF00244	0.570
LIG_14-3-3_CanoR_1	393	402	PF00244	0.556
LIG_14-3-3_CanoR_1	439	449	PF00244	0.561
LIG_14-3-3_CanoR_1	684	689	PF00244	0.561
LIG_14-3-3_CanoR_1	768	774	PF00244	0.552
LIG_14-3-3_CanoR_1	851	860	PF00244	0.600
LIG_14-3-3_CanoR_1	888	892	PF00244	0.506
LIG_14-3-3_CanoR_1	904	910	PF00244	0.652
LIG_14-3-3_CanoR_1	970	978	PF00244	0.513
LIG_Actin_WH2_2	1064	1081	PF00022	0.559
LIG_Actin_WH2_2	839	856	PF00022	0.569
LIG_APCC_ABBA_1	291	296	PF00400	0.232
LIG_APCC_ABBA_1	94	99	PF00400	0.645
LIG_APCC_ABBAyCdc20_2	524	530	PF00400	0.556
LIG_BIR_II_1	1	5	PF00653	0.780
LIG_BRCT_BRCA1_1	1	5	PF00533	0.729
LIG_BRCT_BRCA1_1	134	138	PF00533	0.670
LIG_BRCT_BRCA1_1	410	414	PF00533	0.600
LIG_BRCT_BRCA1_1	464	468	PF00533	0.562
LIG_BRCT_BRCA1_1	753	757	PF00533	0.419
LIG_BRCT_BRCA1_1	90	94	PF00533	0.686
LIG_BRCT_BRCA1_2	134	140	PF00533	0.625
LIG_Clathr_ClatBox_1	628	632	PF01394	0.381
LIG_Clathr_ClatBox_1	869	873	PF01394	0.697
LIG_CSL_BTD_1	260	263	PF09270	0.319
LIG_CSL_BTD_1	377	380	PF09270	0.586
LIG_DLG_GKlike_1	684	691	PF00625	0.561
LIG_EH1_1	886	894	PF00400	0.543
LIG_eIF4E_1	283	289	PF01652	0.396
LIG_eIF4E_1	710	716	PF01652	0.370
LIG_eIF4E_1	887	893	PF01652	0.574
LIG_FHA_1	1135	1141	PF00498	0.470
LIG_FHA_1	1160	1166	PF00498	0.321
LIG_FHA_1	1170	1176	PF00498	0.336
LIG_FHA_1	293	299	PF00498	0.441
LIG_FHA_1	394	400	PF00498	0.553
LIG_FHA_1	530	536	PF00498	0.601
LIG_FHA_1	542	548	PF00498	0.492
LIG_FHA_1	554	560	PF00498	0.598
LIG_FHA_1	660	666	PF00498	0.344
LIG_FHA_1	735	741	PF00498	0.276
LIG_FHA_1	78	84	PF00498	0.697
LIG_FHA_1	835	841	PF00498	0.660
LIG_FHA_1	888	894	PF00498	0.576
LIG_FHA_2	1031	1037	PF00498	0.549
LIG_FHA_2	1149	1155	PF00498	0.344
LIG_FHA_2	12	18	PF00498	0.736
LIG_FHA_2	183	189	PF00498	0.648
LIG_FHA_2	241	247	PF00498	0.514
LIG_FHA_2	580	586	PF00498	0.606
LIG_FHA_2	674	680	PF00498	0.392
LIG_FHA_2	722	728	PF00498	0.302
LIG_FHA_2	800	806	PF00498	0.764
LIG_FHA_2	866	872	PF00498	0.708
LIG_GBD_Chelix_1	298	306	PF00786	0.353
LIG_LIR_Apic_2	1145	1149	PF02991	0.376
LIG_LIR_Apic_2	147	152	PF02991	0.512
LIG_LIR_Apic_2	224	229	PF02991	0.329
LIG_LIR_Apic_2	376	380	PF02991	0.583
LIG_LIR_Apic_2	635	639	PF02991	0.354
LIG_LIR_Apic_2	779	784	PF02991	0.547
LIG_LIR_Gen_1	1065	1075	PF02991	0.587
LIG_LIR_Gen_1	1084	1095	PF02991	0.533
LIG_LIR_Gen_1	185	195	PF02991	0.584
LIG_LIR_Gen_1	228	238	PF02991	0.421
LIG_LIR_Gen_1	413	422	PF02991	0.559
LIG_LIR_Gen_1	481	490	PF02991	0.585
LIG_LIR_Gen_1	504	513	PF02991	0.533
LIG_LIR_Gen_1	622	631	PF02991	0.361
LIG_LIR_Gen_1	696	704	PF02991	0.543
LIG_LIR_Gen_1	880	891	PF02991	0.596
LIG_LIR_Nem_3	1053	1058	PF02991	0.565
LIG_LIR_Nem_3	1065	1071	PF02991	0.579
LIG_LIR_Nem_3	1082	1086	PF02991	0.533
LIG_LIR_Nem_3	1088	1093	PF02991	0.521
LIG_LIR_Nem_3	185	190	PF02991	0.591
LIG_LIR_Nem_3	228	233	PF02991	0.421
LIG_LIR_Nem_3	368	373	PF02991	0.578
LIG_LIR_Nem_3	411	417	PF02991	0.537
LIG_LIR_Nem_3	465	471	PF02991	0.590
LIG_LIR_Nem_3	481	486	PF02991	0.498
LIG_LIR_Nem_3	504	509	PF02991	0.545
LIG_LIR_Nem_3	526	531	PF02991	0.568
LIG_LIR_Nem_3	537	542	PF02991	0.495
LIG_LIR_Nem_3	544	548	PF02991	0.485
LIG_LIR_Nem_3	582	587	PF02991	0.593
LIG_LIR_Nem_3	622	628	PF02991	0.336
LIG_LIR_Nem_3	696	700	PF02991	0.520
LIG_LIR_Nem_3	737	741	PF02991	0.323
LIG_LIR_Nem_3	899	903	PF02991	0.550
LIG_NRBOX	485	491	PF00104	0.602
LIG_PCNA_yPIPBox_3	301	315	PF02747	0.370
LIG_PDZ_Class_1	1185	1190	PF00595	0.478
LIG_Pex14_1	280	284	PF04695	0.319
LIG_Pex14_2	1083	1087	PF04695	0.572
LIG_Pex14_2	195	199	PF04695	0.571
LIG_Pex14_2	226	230	PF04695	0.445
LIG_Pex14_2	693	697	PF04695	0.511
LIG_Pex14_2	741	745	PF04695	0.447
LIG_SH2_CRK	370	374	PF00017	0.595
LIG_SH2_NCK_1	986	990	PF00017	0.494
LIG_SH2_PTP2	250	253	PF00017	0.432
LIG_SH2_SRC	986	989	PF00017	0.567
LIG_SH2_STAP1	284	288	PF00017	0.319
LIG_SH2_STAP1	415	419	PF00017	0.554
LIG_SH2_STAT5	1120	1123	PF00017	0.472
LIG_SH2_STAT5	250	253	PF00017	0.319
LIG_SH2_STAT5	508	511	PF00017	0.570
LIG_SH2_STAT5	531	534	PF00017	0.629
LIG_SH2_STAT5	546	549	PF00017	0.521
LIG_SH2_STAT5	627	630	PF00017	0.384
LIG_SH2_STAT5	743	746	PF00017	0.325
LIG_SH2_STAT5	883	886	PF00017	0.589
LIG_SH2_STAT5	909	912	PF00017	0.582
LIG_SH3_1	1042	1048	PF00018	0.541
LIG_SH3_3	1042	1048	PF00018	0.568
LIG_SH3_3	1089	1095	PF00018	0.567
LIG_SH3_3	1137	1143	PF00018	0.446
LIG_SH3_3	153	159	PF00018	0.585
LIG_SH3_3	166	172	PF00018	0.666
LIG_SH3_3	207	213	PF00018	0.366
LIG_SH3_3	219	225	PF00018	0.409
LIG_SH3_3	398	404	PF00018	0.569
LIG_SH3_3	63	69	PF00018	0.702
LIG_SH3_3	711	717	PF00018	0.357
LIG_SH3_3	72	78	PF00018	0.669
LIG_SH3_3	749	755	PF00018	0.316
LIG_SH3_3	783	789	PF00018	0.647
LIG_SH3_3	869	875	PF00018	0.640
LIG_SUMO_SIM_anti_2	396	403	PF11976	0.621
LIG_SUMO_SIM_anti_2	484	491	PF11976	0.604
LIG_SUMO_SIM_anti_2	747	752	PF11976	0.426
LIG_SUMO_SIM_anti_2	972	978	PF11976	0.452
LIG_SUMO_SIM_par_1	1160	1166	PF11976	0.337
LIG_SUMO_SIM_par_1	1171	1178	PF11976	0.382
LIG_SUMO_SIM_par_1	447	453	PF11976	0.488
LIG_SUMO_SIM_par_1	484	491	PF11976	0.614
LIG_SUMO_SIM_par_1	717	725	PF11976	0.456
LIG_SUMO_SIM_par_1	868	873	PF11976	0.688
LIG_SxIP_EBH_1	102	115	PF03271	0.638
LIG_TRFH_1	713	717	PF08558	0.364
LIG_TYR_ITIM	248	253	PF00017	0.547
LIG_UBA3_1	1182	1189	PF00899	0.393
LIG_UBA3_1	486	494	PF00899	0.568
LIG_UBA3_1	849	857	PF00899	0.603
LIG_WRC_WIRS_1	1158	1163	PF05994	0.348
LIG_WRC_WIRS_1	146	151	PF05994	0.492
LIG_WRC_WIRS_1	374	379	PF05994	0.594
LIG_WRC_WIRS_1	542	547	PF05994	0.491
LIG_WRC_WIRS_1	694	699	PF05994	0.484
LIG_WW_2	66	69	PF00397	0.673
MOD_CDC14_SPxK_1	101	104	PF00782	0.650
MOD_CDK_SPK_2	11	16	PF00069	0.679
MOD_CDK_SPK_2	98	103	PF00069	0.724
MOD_CDK_SPxK_1	98	104	PF00069	0.656
MOD_CDK_SPxxK_3	1044	1051	PF00069	0.590
MOD_CDK_SPxxK_3	677	684	PF00069	0.537
MOD_CK1_1	1061	1067	PF00069	0.554
MOD_CK1_1	1073	1079	PF00069	0.511
MOD_CK1_1	1134	1140	PF00069	0.481
MOD_CK1_1	145	151	PF00069	0.609
MOD_CK1_1	376	382	PF00069	0.569
MOD_CK1_1	42	48	PF00069	0.775
MOD_CK1_1	462	468	PF00069	0.531
MOD_CK1_1	52	58	PF00069	0.794
MOD_CK1_1	570	576	PF00069	0.644
MOD_CK1_1	579	585	PF00069	0.556
MOD_CK1_1	61	67	PF00069	0.654
MOD_CK1_1	772	778	PF00069	0.549
MOD_CK1_1	820	826	PF00069	0.729
MOD_CK1_1	905	911	PF00069	0.655
MOD_CK1_1	993	999	PF00069	0.470
MOD_CK2_1	1030	1036	PF00069	0.566
MOD_CK2_1	11	17	PF00069	0.789
MOD_CK2_1	240	246	PF00069	0.387
MOD_CK2_1	378	384	PF00069	0.601
MOD_CK2_1	4	10	PF00069	0.786
MOD_CK2_1	410	416	PF00069	0.523
MOD_CK2_1	570	576	PF00069	0.654
MOD_CK2_1	579	585	PF00069	0.551
MOD_CK2_1	673	679	PF00069	0.429
MOD_CK2_1	717	723	PF00069	0.414
MOD_CK2_1	799	805	PF00069	0.757
MOD_CK2_1	852	858	PF00069	0.598
MOD_CK2_1	865	871	PF00069	0.537
MOD_CK2_1	905	911	PF00069	0.605
MOD_CMANNOS	897	900	PF00535	0.333
MOD_GlcNHglycan	1033	1036	PF01048	0.806
MOD_GlcNHglycan	162	165	PF01048	0.525
MOD_GlcNHglycan	284	287	PF01048	0.329
MOD_GlcNHglycan	456	459	PF01048	0.408
MOD_GlcNHglycan	532	535	PF01048	0.442
MOD_GlcNHglycan	615	618	PF01048	0.289
MOD_GlcNHglycan	636	639	PF01048	0.463
MOD_GlcNHglycan	645	648	PF01048	0.463
MOD_GlcNHglycan	994	998	PF01048	0.742
MOD_GSK3_1	1005	1012	PF00069	0.509
MOD_GSK3_1	1027	1034	PF00069	0.601
MOD_GSK3_1	1040	1047	PF00069	0.558
MOD_GSK3_1	1058	1065	PF00069	0.396
MOD_GSK3_1	1069	1076	PF00069	0.510
MOD_GSK3_1	1091	1098	PF00069	0.553
MOD_GSK3_1	1123	1130	PF00069	0.490
MOD_GSK3_1	1131	1138	PF00069	0.435
MOD_GSK3_1	1157	1164	PF00069	0.337
MOD_GSK3_1	17	24	PF00069	0.757
MOD_GSK3_1	221	228	PF00069	0.396
MOD_GSK3_1	38	45	PF00069	0.738
MOD_GSK3_1	48	55	PF00069	0.776
MOD_GSK3_1	488	495	PF00069	0.599
MOD_GSK3_1	567	574	PF00069	0.627
MOD_GSK3_1	619	626	PF00069	0.345
MOD_GSK3_1	673	680	PF00069	0.340
MOD_GSK3_1	717	724	PF00069	0.326
MOD_GSK3_1	769	776	PF00069	0.497
MOD_GSK3_1	816	823	PF00069	0.654
MOD_GSK3_1	830	837	PF00069	0.700
MOD_GSK3_1	875	882	PF00069	0.538
MOD_GSK3_1	892	899	PF00069	0.491
MOD_GSK3_1	989	996	PF00069	0.461
MOD_N-GLC_1	1113	1118	PF02516	0.663
MOD_N-GLC_1	1169	1174	PF02516	0.606
MOD_N-GLC_1	182	187	PF02516	0.461
MOD_N-GLC_1	21	26	PF02516	0.592
MOD_N-GLC_1	39	44	PF02516	0.552
MOD_N-GLC_1	440	445	PF02516	0.366
MOD_N-GLC_1	52	57	PF02516	0.425
MOD_N-GLC_1	792	797	PF02516	0.523
MOD_N-GLC_1	825	830	PF02516	0.475
MOD_N-GLC_1	979	984	PF02516	0.413
MOD_N-GLC_1	989	994	PF02516	0.648
MOD_N-GLC_2	308	310	PF02516	0.364
MOD_NEK2_1	1175	1180	PF00069	0.378
MOD_NEK2_1	237	242	PF00069	0.393
MOD_NEK2_1	306	311	PF00069	0.372
MOD_NEK2_1	373	378	PF00069	0.541
MOD_NEK2_1	387	392	PF00069	0.543
MOD_NEK2_1	49	54	PF00069	0.804
MOD_NEK2_1	490	495	PF00069	0.516
MOD_NEK2_1	619	624	PF00069	0.336
MOD_NEK2_1	665	670	PF00069	0.359
MOD_NEK2_1	673	678	PF00069	0.302
MOD_NEK2_1	693	698	PF00069	0.335
MOD_NEK2_1	744	749	PF00069	0.448
MOD_NEK2_1	892	897	PF00069	0.509
MOD_NEK2_2	1021	1026	PF00069	0.492
MOD_NEK2_2	523	528	PF00069	0.619
MOD_NEK2_2	541	546	PF00069	0.491
MOD_NEK2_2	997	1002	PF00069	0.421
MOD_OFUCOSY	303	310	PF10250	0.417
MOD_PIKK_1	1040	1046	PF00454	0.588
MOD_PIKK_1	805	811	PF00454	0.759
MOD_PIKK_1	902	908	PF00454	0.583
MOD_PIKK_1	969	975	PF00454	0.561
MOD_PK_1	1113	1119	PF00069	0.430
MOD_PK_1	943	949	PF00069	0.655
MOD_PKA_2	1061	1067	PF00069	0.574
MOD_PKA_2	1073	1079	PF00069	0.488
MOD_PKA_2	203	209	PF00069	0.324
MOD_PKA_2	363	369	PF00069	0.549
MOD_PKA_2	523	529	PF00069	0.595
MOD_PKA_2	553	559	PF00069	0.547
MOD_PKA_2	659	665	PF00069	0.336
MOD_PKA_2	820	826	PF00069	0.724
MOD_PKA_2	887	893	PF00069	0.587
MOD_PKA_2	969	975	PF00069	0.511
MOD_Plk_1	1113	1119	PF00069	0.458
MOD_Plk_1	142	148	PF00069	0.644
MOD_Plk_1	167	173	PF00069	0.745
MOD_Plk_1	182	188	PF00069	0.662
MOD_Plk_1	39	45	PF00069	0.683
MOD_Plk_1	440	446	PF00069	0.551
MOD_Plk_1	52	58	PF00069	0.692
MOD_Plk_1	722	728	PF00069	0.314
MOD_Plk_1	792	798	PF00069	0.751
MOD_Plk_1	825	831	PF00069	0.707
MOD_Plk_1	865	871	PF00069	0.698
MOD_Plk_1	879	885	PF00069	0.452
MOD_Plk_1	979	985	PF00069	0.424
MOD_Plk_2-3	142	148	PF00069	0.684
MOD_Plk_2-3	865	871	PF00069	0.709
MOD_Plk_4	1073	1079	PF00069	0.527
MOD_Plk_4	1113	1119	PF00069	0.410
MOD_Plk_4	134	140	PF00069	0.667
MOD_Plk_4	182	188	PF00069	0.640
MOD_Plk_4	232	238	PF00069	0.353
MOD_Plk_4	262	268	PF00069	0.412
MOD_Plk_4	373	379	PF00069	0.556
MOD_Plk_4	541	547	PF00069	0.492
MOD_Plk_4	567	573	PF00069	0.641
MOD_Plk_4	654	660	PF00069	0.288
MOD_Plk_4	665	671	PF00069	0.286
MOD_Plk_4	693	699	PF00069	0.484
MOD_Plk_4	744	750	PF00069	0.398
MOD_Plk_4	753	759	PF00069	0.272
MOD_Plk_4	769	775	PF00069	0.483
MOD_Plk_4	77	83	PF00069	0.696
MOD_Plk_4	792	798	PF00069	0.677
MOD_Plk_4	879	885	PF00069	0.578
MOD_Plk_4	887	893	PF00069	0.506
MOD_ProDKin_1	1044	1050	PF00069	0.551
MOD_ProDKin_1	1091	1097	PF00069	0.564
MOD_ProDKin_1	11	17	PF00069	0.706
MOD_ProDKin_1	113	119	PF00069	0.739
MOD_ProDKin_1	1135	1141	PF00069	0.508
MOD_ProDKin_1	221	227	PF00069	0.423
MOD_ProDKin_1	376	382	PF00069	0.585
MOD_ProDKin_1	61	67	PF00069	0.636
MOD_ProDKin_1	677	683	PF00069	0.537
MOD_ProDKin_1	74	80	PF00069	0.656
MOD_ProDKin_1	751	757	PF00069	0.349
MOD_ProDKin_1	98	104	PF00069	0.681
MOD_SUMO_rev_2	1166	1175	PF00179	0.333
MOD_SUMO_rev_2	450	457	PF00179	0.590
TRG_DiLeu_BaEn_1	1171	1176	PF01217	0.331
TRG_DiLeu_BaEn_1	354	359	PF01217	0.598
TRG_DiLeu_BaEn_1	485	490	PF01217	0.604
TRG_DiLeu_BaEn_2	588	594	PF01217	0.614
TRG_DiLeu_LyEn_5	354	359	PF01217	0.608
TRG_ENDOCYTIC_2	250	253	PF00928	0.392
TRG_ENDOCYTIC_2	284	287	PF00928	0.333
TRG_ENDOCYTIC_2	347	350	PF00928	0.364
TRG_ENDOCYTIC_2	370	373	PF00928	0.598
TRG_ENDOCYTIC_2	415	418	PF00928	0.546
TRG_ENDOCYTIC_2	704	707	PF00928	0.331
TRG_ENDOCYTIC_2	710	713	PF00928	0.316
TRG_ENDOCYTIC_2	743	746	PF00928	0.314
TRG_ENDOCYTIC_2	883	886	PF00928	0.590
TRG_ER_diArg_1	1121	1123	PF00400	0.522
TRG_ER_diArg_1	179	181	PF00400	0.727
TRG_ER_diArg_1	299	301	PF00400	0.517
TRG_ER_diArg_1	437	440	PF00400	0.550
TRG_ER_diArg_1	601	604	PF00400	0.521
TRG_ER_diArg_1	850	852	PF00400	0.606
TRG_ER_diArg_1	914	916	PF00400	0.620
TRG_Pf-PMV_PEXEL_1	1015	1019	PF00026	0.725
TRG_Pf-PMV_PEXEL_1	827	831	PF00026	0.378
TRG_Pf-PMV_PEXEL_1	844	848	PF00026	0.406
TRG_Pf-PMV_PEXEL_1	867	871	PF00026	0.485
TRG_PTS1	1187	1190	PF00515	0.492

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2I7	Leptomonas seymouri	67%	100%
A0A0S4ILS6	Bodo saltans	25%	100%
A0A0S4JFC0	Bodo saltans	28%	100%
A0A0S4JFT8	Bodo saltans	28%	100%
A0A1X0NTN6	Trypanosomatidae	34%	96%
A0A1X0P637	Trypanosomatidae	52%	100%
A0A3Q8IJB5	Leishmania donovani	93%	100%
A0A3R7MLB2	Trypanosoma rangeli	50%	100%
A4HN28	Leishmania braziliensis	75%	100%
A4IBP2	Leishmania infantum	94%	100%
C9ZYX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
E9B6N6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
V5BY09	Trypanosoma cruzi	50%	100%