Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AFE6_LEIMA

TriTrypDb:

LmjF.35.3220 , LMJLV39_350039600 , LMJSD75_350039000

Length:

169


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005930	axoneme	2	2
GO:0110165	cellular anatomical entity	1	2

E9AFE6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AFE6


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	156	160	PF00656	0.508
CLV_NRD_NRD_1	12	14	PF00675	0.679
CLV_PCSK_SKI1_1	36	40	PF00082	0.573
CLV_PCSK_SKI1_1	72	76	PF00082	0.593
DOC_USP7_MATH_1	88	92	PF00917	0.526
DOC_USP7_MATH_1	9	13	PF00917	0.668
DOC_USP7_UBL2_3	10	14	PF12436	0.623
DOC_WW_Pin1_4	48	53	PF00397	0.448
LIG_14-3-3_CanoR_1	67	76	PF00244	0.557
LIG_BIR_II_1	1	5	PF00653	0.733
LIG_FHA_1	56	62	PF00498	0.510
LIG_FHA_1	88	94	PF00498	0.463
LIG_FHA_2	28	34	PF00498	0.466
LIG_FHA_2	58	64	PF00498	0.549
LIG_FHA_2	87	93	PF00498	0.480
LIG_LIR_LC3C_4	44	49	PF02991	0.518
LIG_LIR_Nem_3	107	113	PF02991	0.438
LIG_SH2_CRK	85	89	PF00017	0.490
LIG_SH2_NCK_1	85	89	PF00017	0.490
LIG_SH2_SRC	108	111	PF00017	0.496
LIG_SH3_1	15	21	PF00018	0.588
LIG_SH3_3	15	21	PF00018	0.586
LIG_SH3_3	46	52	PF00018	0.416
LIG_SUMO_SIM_anti_2	44	51	PF11976	0.509
LIG_SUMO_SIM_par_1	44	51	PF11976	0.398
LIG_TRAF2_1	144	147	PF00917	0.582
MOD_CK1_1	70	76	PF00069	0.541
MOD_CK2_1	57	63	PF00069	0.547
MOD_CK2_1	86	92	PF00069	0.492
MOD_GlcNHglycan	43	46	PF01048	0.525
MOD_GlcNHglycan	7	10	PF01048	0.659
MOD_GlcNHglycan	72	75	PF01048	0.542
MOD_GSK3_1	1	8	PF00069	0.644
MOD_GSK3_1	70	77	PF00069	0.534
MOD_GSK3_1	93	100	PF00069	0.539
MOD_N-GLC_1	68	73	PF02516	0.514
MOD_NEK2_1	1	6	PF00069	0.722
MOD_NEK2_1	104	109	PF00069	0.328
MOD_NEK2_1	131	136	PF00069	0.529
MOD_NEK2_1	68	73	PF00069	0.504
MOD_NEK2_1	97	102	PF00069	0.446
MOD_PIKK_1	131	137	PF00454	0.537
MOD_PK_1	3	9	PF00069	0.579
MOD_Plk_1	36	42	PF00069	0.345
MOD_Plk_4	57	63	PF00069	0.483
MOD_ProDKin_1	48	54	PF00069	0.454
TRG_DiLeu_BaEn_1	123	128	PF01217	0.449
TRG_ENDOCYTIC_2	110	113	PF00928	0.504
TRG_NLS_MonoExtC_3	9	14	PF00514	0.690
TRG_NLS_MonoExtN_4	10	17	PF00514	0.654


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCS8	Leptomonas seymouri	54%	97%
A0A1X0P5D6	Trypanosomatidae	44%	100%
A0A3R7K5Y2	Trypanosoma rangeli	36%	97%
A0A3S7X9I9	Leishmania donovani	95%	99%
A4HMY9	Leishmania braziliensis	77%	100%
A4IBL3	Leishmania infantum	95%	99%
C9ZZ27	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	99%
E9B6K1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
V5BD44	Trypanosoma cruzi	40%	100%