LeishMANIAdb
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Cilia- and flagella-associated protein 157

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Cilia- and flagella-associated protein 157
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9AF99_LEIMA
TriTrypDb:
LmjF.35.2750 , LMJLV39_350034500 * , LMJSD75_350033800 *
Length:
429

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AF99
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AF99

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 103 107 PF00656 0.605
CLV_NRD_NRD_1 124 126 PF00675 0.627
CLV_NRD_NRD_1 178 180 PF00675 0.559
CLV_NRD_NRD_1 318 320 PF00675 0.637
CLV_NRD_NRD_1 407 409 PF00675 0.537
CLV_PCSK_KEX2_1 123 125 PF00082 0.599
CLV_PCSK_KEX2_1 204 206 PF00082 0.656
CLV_PCSK_KEX2_1 229 231 PF00082 0.530
CLV_PCSK_KEX2_1 237 239 PF00082 0.573
CLV_PCSK_KEX2_1 318 320 PF00082 0.637
CLV_PCSK_KEX2_1 407 409 PF00082 0.579
CLV_PCSK_PC1ET2_1 123 125 PF00082 0.579
CLV_PCSK_PC1ET2_1 204 206 PF00082 0.602
CLV_PCSK_PC1ET2_1 229 231 PF00082 0.545
CLV_PCSK_PC1ET2_1 237 239 PF00082 0.573
CLV_PCSK_SKI1_1 132 136 PF00082 0.653
CLV_PCSK_SKI1_1 219 223 PF00082 0.585
CLV_PCSK_SKI1_1 407 411 PF00082 0.543
CLV_Separin_Metazoa 391 395 PF03568 0.656
DEG_APCC_DBOX_1 131 139 PF00400 0.627
DEG_APCC_DBOX_1 170 178 PF00400 0.475
DEG_APCC_DBOX_1 320 328 PF00400 0.658
DEG_Nend_Nbox_1 1 3 PF02207 0.543
DOC_CKS1_1 158 163 PF01111 0.656
DOC_CYCLIN_RxL_1 129 136 PF00134 0.621
DOC_MAPK_FxFP_2 352 355 PF00069 0.641
DOC_MAPK_gen_1 318 326 PF00069 0.650
DOC_MAPK_gen_1 407 413 PF00069 0.577
DOC_PP2B_LxvP_1 46 49 PF13499 0.701
DOC_PP4_FxxP_1 352 355 PF00568 0.641
DOC_USP7_MATH_1 100 104 PF00917 0.688
DOC_USP7_MATH_1 13 17 PF00917 0.740
DOC_USP7_MATH_1 276 280 PF00917 0.534
DOC_USP7_MATH_1 425 429 PF00917 0.678
DOC_WW_Pin1_4 157 162 PF00397 0.680
DOC_WW_Pin1_4 26 31 PF00397 0.593
DOC_WW_Pin1_4 9 14 PF00397 0.692
LIG_BIR_III_4 106 110 PF00653 0.628
LIG_BIR_III_4 334 338 PF00653 0.656
LIG_eIF4E_1 372 378 PF01652 0.649
LIG_FHA_1 56 62 PF00498 0.816
LIG_FHA_2 103 109 PF00498 0.481
LIG_NRBOX 134 140 PF00104 0.629
LIG_SH2_CRK 338 342 PF00017 0.566
LIG_SH2_NCK_1 338 342 PF00017 0.554
LIG_SH2_SRC 338 341 PF00017 0.556
LIG_SH2_STAP1 246 250 PF00017 0.528
LIG_SH2_STAT3 372 375 PF00017 0.647
LIG_SH3_3 139 145 PF00018 0.669
LIG_SH3_3 46 52 PF00018 0.821
LIG_TRAF2_1 166 169 PF00917 0.637
LIG_TRAF2_1 249 252 PF00917 0.523
LIG_TRAF2_1 279 282 PF00917 0.554
LIG_TRAF2_1 82 85 PF00917 0.707
LIG_UBA3_1 398 403 PF00899 0.636
MOD_CK1_1 344 350 PF00069 0.579
MOD_CK2_1 102 108 PF00069 0.567
MOD_CK2_1 156 162 PF00069 0.711
MOD_CK2_1 194 200 PF00069 0.636
MOD_CK2_1 276 282 PF00069 0.556
MOD_GlcNHglycan 102 105 PF01048 0.623
MOD_GlcNHglycan 15 18 PF01048 0.746
MOD_GlcNHglycan 212 216 PF01048 0.650
MOD_GlcNHglycan 34 37 PF01048 0.791
MOD_GlcNHglycan 341 344 PF01048 0.783
MOD_GSK3_1 140 147 PF00069 0.717
MOD_GSK3_1 179 186 PF00069 0.555
MOD_GSK3_1 421 428 PF00069 0.781
MOD_GSK3_1 51 58 PF00069 0.663
MOD_GSK3_1 9 16 PF00069 0.807
MOD_N-GLC_1 13 18 PF02516 0.687
MOD_N-GLC_1 302 307 PF02516 0.619
MOD_N-GLC_1 384 389 PF02516 0.580
MOD_N-GLC_1 77 82 PF02516 0.754
MOD_NEK2_1 371 376 PF00069 0.647
MOD_NEK2_2 17 22 PF00069 0.576
MOD_PIKK_1 258 264 PF00454 0.501
MOD_PIKK_1 366 372 PF00454 0.659
MOD_PKA_1 179 185 PF00069 0.555
MOD_PKA_2 186 192 PF00069 0.551
MOD_Plk_1 302 308 PF00069 0.622
MOD_Plk_2-3 194 200 PF00069 0.470
MOD_Plk_2-3 328 334 PF00069 0.712
MOD_ProDKin_1 157 163 PF00069 0.675
MOD_ProDKin_1 26 32 PF00069 0.593
MOD_ProDKin_1 9 15 PF00069 0.693
TRG_DiLeu_BaEn_1 85 90 PF01217 0.678
TRG_DiLeu_BaLyEn_6 134 139 PF01217 0.623
TRG_ENDOCYTIC_2 338 341 PF00928 0.567
TRG_ER_diArg_1 124 126 PF00400 0.653
TRG_ER_diArg_1 317 319 PF00400 0.547
TRG_ER_diArg_1 320 323 PF00400 0.532
TRG_ER_diArg_1 406 408 PF00400 0.577
TRG_NES_CRM1_1 400 412 PF08389 0.573
TRG_Pf-PMV_PEXEL_1 116 120 PF00026 0.606
TRG_Pf-PMV_PEXEL_1 137 141 PF00026 0.724
TRG_Pf-PMV_PEXEL_1 179 183 PF00026 0.601
TRG_Pf-PMV_PEXEL_1 19 24 PF00026 0.573
TRG_Pf-PMV_PEXEL_1 308 312 PF00026 0.634
TRG_Pf-PMV_PEXEL_1 318 322 PF00026 0.477

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P8Q8 Leptomonas seymouri 43% 73%
A0A3Q8IJI3 Leishmania donovani 88% 73%
A4IBE3 Leishmania infantum 87% 100%
E9AIW7 Leishmania braziliensis 62% 73%
E9B6F4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS