Related to many other eukaryotic palmitoyltransferases (e.g. mammalian ZDHHC4/9/14/24)
Source | Evidence on protein | Close homologs |
---|---|---|
Cuervo et al. | no | yes: 0 |
Hassani et al. | no | yes: 0 |
Forrest at al. (metacyclic) | no | yes: 0 |
Forrest at al. (procyclic) | no | yes: 0 |
Silverman et al. | no | yes: 0 |
Pissara et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pires et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Silverman et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Jamdhade et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
DeepLoc | ||
SignalP6 | no | yes: 0, no: 11 |
NetGPI | no | yes: 0, no: 11 |
Term | Name | Level | Count |
---|---|---|---|
GO:0005783 | endoplasmic reticulum | 5 | 2 |
GO:0005794 | Golgi apparatus | 5 | 2 |
GO:0016020 | membrane | 2 | 12 |
GO:0043226 | organelle | 2 | 2 |
GO:0043227 | membrane-bounded organelle | 3 | 2 |
GO:0043229 | intracellular organelle | 3 | 2 |
GO:0043231 | intracellular membrane-bounded organelle | 4 | 2 |
GO:0110165 | cellular anatomical entity | 1 | 12 |
Related structures:
AlphaFold database: E9AF82
Term | Name | Level | Count |
---|---|---|---|
GO:0006497 | protein lipidation | 5 | 2 |
GO:0006605 | protein targeting | 5 | 2 |
GO:0006612 | protein targeting to membrane | 5 | 2 |
GO:0006807 | nitrogen compound metabolic process | 2 | 2 |
GO:0006810 | transport | 3 | 2 |
GO:0006886 | intracellular protein transport | 4 | 2 |
GO:0008104 | protein localization | 4 | 2 |
GO:0008152 | metabolic process | 1 | 2 |
GO:0009987 | cellular process | 1 | 2 |
GO:0015031 | protein transport | 4 | 2 |
GO:0018193 | peptidyl-amino acid modification | 5 | 2 |
GO:0018198 | peptidyl-cysteine modification | 6 | 2 |
GO:0018230 | peptidyl-L-cysteine S-palmitoylation | 7 | 2 |
GO:0018231 | peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine | 7 | 2 |
GO:0018345 | protein palmitoylation | 6 | 2 |
GO:0019538 | protein metabolic process | 3 | 2 |
GO:0033036 | macromolecule localization | 2 | 2 |
GO:0036211 | protein modification process | 4 | 2 |
GO:0043170 | macromolecule metabolic process | 3 | 2 |
GO:0043412 | macromolecule modification | 4 | 2 |
GO:0043543 | protein acylation | 5 | 2 |
GO:0044238 | primary metabolic process | 2 | 2 |
GO:0045184 | establishment of protein localization | 3 | 2 |
GO:0046907 | intracellular transport | 3 | 2 |
GO:0051179 | localization | 1 | 2 |
GO:0051234 | establishment of localization | 2 | 2 |
GO:0051641 | cellular localization | 2 | 2 |
GO:0051649 | establishment of localization in cell | 3 | 2 |
GO:0051668 | localization within membrane | 3 | 2 |
GO:0070727 | cellular macromolecule localization | 3 | 2 |
GO:0071702 | organic substance transport | 4 | 2 |
GO:0071704 | organic substance metabolic process | 2 | 2 |
GO:0071705 | nitrogen compound transport | 4 | 2 |
GO:0072657 | protein localization to membrane | 4 | 2 |
GO:0090150 | establishment of protein localization to membrane | 4 | 2 |
GO:1901564 | organonitrogen compound metabolic process | 3 | 2 |
Term | Name | Level | Count |
---|---|---|---|
GO:0003824 | catalytic activity | 1 | 12 |
GO:0016409 | palmitoyltransferase activity | 5 | 12 |
GO:0016417 | S-acyltransferase activity | 5 | 12 |
GO:0016740 | transferase activity | 2 | 12 |
GO:0016746 | acyltransferase activity | 3 | 12 |
GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | 4 | 12 |
GO:0019706 | protein-cysteine S-palmitoyltransferase activity | 4 | 12 |
GO:0019707 | protein-cysteine S-acyltransferase activity | 3 | 12 |
GO:0140096 | catalytic activity, acting on a protein | 2 | 12 |
Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|
CLV_NRD_NRD_1 | 263 | 265 | PF00675 | 0.368 |
CLV_PCSK_KEX2_1 | 146 | 148 | PF00082 | 0.208 |
CLV_PCSK_KEX2_1 | 263 | 265 | PF00082 | 0.335 |
CLV_PCSK_KEX2_1 | 9 | 11 | PF00082 | 0.365 |
CLV_PCSK_PC1ET2_1 | 146 | 148 | PF00082 | 0.224 |
CLV_PCSK_PC1ET2_1 | 9 | 11 | PF00082 | 0.365 |
CLV_PCSK_SKI1_1 | 263 | 267 | PF00082 | 0.326 |
CLV_PCSK_SKI1_1 | 9 | 13 | PF00082 | 0.378 |
DEG_APCC_DBOX_1 | 184 | 192 | PF00400 | 0.211 |
DOC_CDC14_PxL_1 | 32 | 40 | PF14671 | 0.284 |
DOC_CYCLIN_RxL_1 | 260 | 267 | PF00134 | 0.455 |
DOC_MAPK_gen_1 | 253 | 261 | PF00069 | 0.427 |
DOC_MAPK_gen_1 | 9 | 17 | PF00069 | 0.668 |
DOC_PP1_RVXF_1 | 14 | 20 | PF00149 | 0.654 |
DOC_PP2B_LxvP_1 | 208 | 211 | PF13499 | 0.284 |
DOC_USP7_MATH_1 | 221 | 225 | PF00917 | 0.438 |
DOC_USP7_MATH_1 | 91 | 95 | PF00917 | 0.632 |
DOC_WW_Pin1_4 | 264 | 269 | PF00397 | 0.626 |
LIG_14-3-3_CanoR_1 | 116 | 125 | PF00244 | 0.424 |
LIG_14-3-3_CanoR_1 | 234 | 243 | PF00244 | 0.581 |
LIG_BRCT_BRCA1_1 | 175 | 179 | PF00533 | 0.211 |
LIG_deltaCOP1_diTrp_1 | 26 | 32 | PF00928 | 0.420 |
LIG_deltaCOP1_diTrp_1 | 53 | 59 | PF00928 | 0.238 |
LIG_eIF4E_1 | 57 | 63 | PF01652 | 0.360 |
LIG_FHA_1 | 109 | 115 | PF00498 | 0.429 |
LIG_FHA_1 | 157 | 163 | PF00498 | 0.265 |
LIG_FHA_1 | 194 | 200 | PF00498 | 0.283 |
LIG_FHA_1 | 40 | 46 | PF00498 | 0.349 |
LIG_FHA_1 | 63 | 69 | PF00498 | 0.321 |
LIG_FHA_1 | 70 | 76 | PF00498 | 0.331 |
LIG_FHA_2 | 223 | 229 | PF00498 | 0.392 |
LIG_GBD_Chelix_1 | 200 | 208 | PF00786 | 0.377 |
LIG_LIR_Gen_1 | 159 | 168 | PF02991 | 0.339 |
LIG_LIR_Gen_1 | 170 | 179 | PF02991 | 0.379 |
LIG_LIR_Gen_1 | 26 | 36 | PF02991 | 0.495 |
LIG_LIR_Gen_1 | 41 | 50 | PF02991 | 0.158 |
LIG_LIR_Gen_1 | 56 | 66 | PF02991 | 0.147 |
LIG_LIR_Nem_3 | 148 | 152 | PF02991 | 0.402 |
LIG_LIR_Nem_3 | 159 | 164 | PF02991 | 0.236 |
LIG_LIR_Nem_3 | 170 | 174 | PF02991 | 0.379 |
LIG_LIR_Nem_3 | 26 | 31 | PF02991 | 0.536 |
LIG_LIR_Nem_3 | 41 | 47 | PF02991 | 0.148 |
LIG_LIR_Nem_3 | 53 | 57 | PF02991 | 0.155 |
LIG_LIR_Nem_3 | 60 | 66 | PF02991 | 0.252 |
LIG_PDZ_Class_2 | 275 | 280 | PF00595 | 0.584 |
LIG_Pex14_1 | 28 | 32 | PF04695 | 0.447 |
LIG_Pex14_2 | 151 | 155 | PF04695 | 0.247 |
LIG_Pex14_2 | 40 | 44 | PF04695 | 0.402 |
LIG_Pex14_2 | 59 | 63 | PF04695 | 0.458 |
LIG_SH2_PTP2 | 165 | 168 | PF00017 | 0.326 |
LIG_SH2_PTP2 | 216 | 219 | PF00017 | 0.442 |
LIG_SH2_STAT5 | 165 | 168 | PF00017 | 0.305 |
LIG_SH2_STAT5 | 216 | 219 | PF00017 | 0.437 |
LIG_SH2_STAT5 | 257 | 260 | PF00017 | 0.521 |
LIG_SH2_STAT5 | 57 | 60 | PF00017 | 0.281 |
LIG_SH3_3 | 30 | 36 | PF00018 | 0.284 |
LIG_SH3_3 | 44 | 50 | PF00018 | 0.349 |
LIG_SH3_3 | 78 | 84 | PF00018 | 0.484 |
LIG_SUMO_SIM_anti_2 | 170 | 178 | PF11976 | 0.360 |
LIG_SUMO_SIM_par_1 | 170 | 178 | PF11976 | 0.349 |
LIG_SUMO_SIM_par_1 | 64 | 69 | PF11976 | 0.348 |
LIG_SUMO_SIM_par_1 | 71 | 76 | PF11976 | 0.382 |
LIG_TYR_ITIM | 163 | 168 | PF00017 | 0.247 |
LIG_WRC_WIRS_1 | 158 | 163 | PF05994 | 0.460 |
LIG_WRC_WIRS_1 | 168 | 173 | PF05994 | 0.198 |
LIG_WW_3 | 116 | 120 | PF00397 | 0.411 |
MOD_CDK_SPxxK_3 | 264 | 271 | PF00069 | 0.533 |
MOD_CK1_1 | 222 | 228 | PF00069 | 0.480 |
MOD_CK2_1 | 222 | 228 | PF00069 | 0.392 |
MOD_Cter_Amidation | 144 | 147 | PF01082 | 0.306 |
MOD_GlcNHglycan | 219 | 222 | PF01048 | 0.282 |
MOD_GlcNHglycan | 238 | 241 | PF01048 | 0.308 |
MOD_GlcNHglycan | 253 | 256 | PF01048 | 0.262 |
MOD_GSK3_1 | 217 | 224 | PF00069 | 0.460 |
MOD_GSK3_1 | 39 | 46 | PF00069 | 0.405 |
MOD_GSK3_1 | 53 | 60 | PF00069 | 0.141 |
MOD_GSK3_1 | 62 | 69 | PF00069 | 0.283 |
MOD_GSK3_1 | 85 | 92 | PF00069 | 0.539 |
MOD_N-GLC_1 | 222 | 227 | PF02516 | 0.202 |
MOD_NEK2_1 | 156 | 161 | PF00069 | 0.265 |
MOD_NEK2_1 | 167 | 172 | PF00069 | 0.160 |
MOD_NEK2_1 | 191 | 196 | PF00069 | 0.230 |
MOD_NEK2_1 | 219 | 224 | PF00069 | 0.445 |
MOD_NEK2_1 | 38 | 43 | PF00069 | 0.360 |
MOD_NEK2_1 | 62 | 67 | PF00069 | 0.280 |
MOD_NEK2_1 | 71 | 76 | PF00069 | 0.258 |
MOD_NEK2_2 | 145 | 150 | PF00069 | 0.411 |
MOD_OFUCOSY | 106 | 112 | PF10250 | 0.242 |
MOD_OFUCOSY | 137 | 143 | PF10250 | 0.224 |
MOD_PIKK_1 | 229 | 235 | PF00454 | 0.575 |
MOD_PIKK_1 | 85 | 91 | PF00454 | 0.559 |
MOD_PKA_2 | 118 | 124 | PF00069 | 0.411 |
MOD_Plk_1 | 222 | 228 | PF00069 | 0.497 |
MOD_Plk_4 | 157 | 163 | PF00069 | 0.303 |
MOD_Plk_4 | 39 | 45 | PF00069 | 0.341 |
MOD_Plk_4 | 53 | 59 | PF00069 | 0.131 |
MOD_ProDKin_1 | 264 | 270 | PF00069 | 0.629 |
MOD_SUMO_rev_2 | 176 | 182 | PF00179 | 0.211 |
TRG_DiLeu_BaEn_1 | 184 | 189 | PF01217 | 0.211 |
TRG_ENDOCYTIC_2 | 165 | 168 | PF00928 | 0.317 |
TRG_ENDOCYTIC_2 | 216 | 219 | PF00928 | 0.421 |
TRG_ER_diArg_1 | 14 | 17 | PF00400 | 0.627 |
TRG_ER_diArg_1 | 262 | 264 | PF00400 | 0.575 |
TRG_ER_diArg_1 | 271 | 274 | PF00400 | 0.614 |
Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|
A0A0N1HZ19 | Leptomonas seymouri | 25% | 80% |
A0A0S4INR8 | Bodo saltans | 30% | 94% |
A0A0S4IT15 | Bodo saltans | 29% | 79% |
A0A0S4IXZ6 | Bodo saltans | 28% | 100% |
A0A0S4KJ22 | Bodo saltans | 38% | 92% |
A0A0S4KJ92 | Bodo saltans | 27% | 100% |
A0A1X0NY23 | Trypanosomatidae | 26% | 94% |
A0A1X0P5Q8 | Trypanosomatidae | 42% | 87% |
A0A3Q8ICY2 | Leishmania donovani | 28% | 79% |
A0A3Q8IIC8 | Leishmania donovani | 95% | 100% |
A0A3R7N519 | Trypanosoma rangeli | 34% | 94% |
A0A3R7P4J6 | Trypanosoma rangeli | 32% | 94% |
A0A422NE16 | Trypanosoma rangeli | 44% | 86% |
A4HCH5 | Leishmania braziliensis | 26% | 70% |
A4HG63 | Leishmania braziliensis | 27% | 78% |
A4HMS9 | Leishmania braziliensis | 80% | 100% |
A4I395 | Leishmania infantum | 28% | 79% |
A4IBG8 | Leishmania infantum | 95% | 100% |
D0A7S1 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 31% | 92% |
E7F587 | Danio rerio | 23% | 87% |
E9AVW7 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 26% | 71% |
E9AZI3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 28% | 79% |
E9B6D8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 92% | 100% |
O74384 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 32% | 80% |
O80685 | Arabidopsis thaliana | 27% | 68% |
P0C7U3 | Homo sapiens | 25% | 75% |
Q2TGJ1 | Rattus norvegicus | 33% | 73% |
Q4Q8P8 | Leishmania major | 25% | 79% |
Q5M757 | Arabidopsis thaliana | 27% | 96% |
Q5PNZ1 | Arabidopsis thaliana | 25% | 68% |
Q5Y5T2 | Mus musculus | 32% | 74% |
Q6BHT4 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 23% | 75% |
Q6CQB5 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 30% | 79% |
Q6FSS4 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 28% | 86% |
Q7ZVN4 | Danio rerio | 32% | 72% |
Q8VYS8 | Arabidopsis thaliana | 26% | 69% |
Q9FLM3 | Arabidopsis thaliana | 30% | 68% |
Q9H8X9 | Homo sapiens | 25% | 68% |
Q9NUE0 | Homo sapiens | 30% | 72% |
Q9SB58 | Arabidopsis thaliana | 29% | 69% |
V5B8P9 | Trypanosoma cruzi | 25% | 80% |
V5BCH8 | Trypanosoma cruzi | 33% | 93% |
V5C316 | Trypanosoma cruzi | 43% | 85% |