Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

E9AF30_LEIMA

TriTrypDb:

LmjF.35.2075

Length:

234

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AF30

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AF30

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	37	39	PF00675	0.626
CLV_PCSK_KEX2_1	37	39	PF00082	0.626
CLV_PCSK_PC7_1	33	39	PF00082	0.628
CLV_PCSK_SKI1_1	160	164	PF00082	0.656
DEG_APCC_DBOX_1	198	206	PF00400	0.583
DEG_APCC_DBOX_1	37	45	PF00400	0.809
DEG_Nend_Nbox_1	1	3	PF02207	0.839
DOC_CDC14_PxL_1	122	130	PF14671	0.840
DOC_CKS1_1	102	107	PF01111	0.659
DOC_CKS1_1	87	92	PF01111	0.848
DOC_CYCLIN_yCln2_LP_2	155	161	PF00134	0.859
DOC_CYCLIN_yCln2_LP_2	165	171	PF00134	0.729
DOC_MAPK_DCC_7	199	207	PF00069	0.819
DOC_MAPK_gen_1	37	43	PF00069	0.810
DOC_MAPK_MEF2A_6	160	169	PF00069	0.856
DOC_MAPK_MEF2A_6	199	207	PF00069	0.819
DOC_MAPK_NFAT4_5	160	168	PF00069	0.856
DOC_PP1_RVXF_1	8	14	PF00149	0.802
DOC_PP2B_LxvP_1	155	158	PF13499	0.859
DOC_PP2B_LxvP_1	165	168	PF13499	0.731
DOC_PP2B_LxvP_1	179	182	PF13499	0.664
DOC_PP2B_LxvP_1	200	203	PF13499	0.583
DOC_PP2B_PxIxI_1	185	191	PF00149	0.683
DOC_PP4_FxxP_1	102	105	PF00568	0.637
DOC_PP4_FxxP_1	85	88	PF00568	0.866
DOC_USP7_MATH_1	106	110	PF00917	0.612
DOC_USP7_MATH_1	127	131	PF00917	0.849
DOC_USP7_MATH_1	220	224	PF00917	0.583
DOC_USP7_MATH_1	88	92	PF00917	0.844
DOC_WW_Pin1_4	101	106	PF00397	0.664
DOC_WW_Pin1_4	167	172	PF00397	0.854
DOC_WW_Pin1_4	46	51	PF00397	0.829
DOC_WW_Pin1_4	54	59	PF00397	0.726
DOC_WW_Pin1_4	71	76	PF00397	0.625
DOC_WW_Pin1_4	86	91	PF00397	0.667
LIG_14-3-3_CanoR_1	133	139	PF00244	0.853
LIG_14-3-3_CanoR_1	144	148	PF00244	0.721
LIG_14-3-3_CanoR_1	199	203	PF00244	0.583
LIG_14-3-3_CanoR_1	23	29	PF00244	0.828
LIG_14-3-3_CanoR_1	33	41	PF00244	0.696
LIG_14-3-3_CanoR_1	53	58	PF00244	0.583
LIG_14-3-3_CterR_2	231	234	PF00244	0.583
LIG_Actin_WH2_2	40	55	PF00022	0.820
LIG_APCC_ABBAyCdc20_2	16	22	PF00400	0.823
LIG_BRCT_BRCA1_1	173	177	PF00533	0.853
LIG_DCNL_PONY_1	1	4	PF03556	0.838
LIG_EVH1_2	203	207	PF00568	0.651
LIG_FHA_1	102	108	PF00498	0.722
LIG_FHA_1	65	71	PF00498	0.811
LIG_FHA_1	92	98	PF00498	0.844
LIG_LIR_Gen_1	121	129	PF02991	0.838
LIG_LIR_Gen_1	137	145	PF02991	0.653
LIG_LIR_Gen_1	36	47	PF02991	0.810
LIG_LIR_Nem_3	121	125	PF02991	0.831
LIG_LIR_Nem_3	137	141	PF02991	0.652
LIG_LIR_Nem_3	164	169	PF02991	0.856
LIG_LIR_Nem_3	36	42	PF02991	0.812
LIG_MYND_1	171	175	PF01753	0.850
LIG_MYND_1	50	54	PF01753	0.842
LIG_PCNA_TLS_4	160	167	PF02747	0.856
LIG_SH2_SRC	18	21	PF00017	0.823
LIG_SH2_STAT5	101	104	PF00017	0.855
LIG_SH2_STAT5	18	21	PF00017	0.823
LIG_SH2_STAT5	63	66	PF00017	0.792
LIG_SH3_3	123	129	PF00018	0.843
LIG_SH3_3	165	171	PF00018	0.854
LIG_SH3_3	179	185	PF00018	0.664
LIG_SH3_3	205	211	PF00018	0.652
LIG_SH3_3	44	50	PF00018	0.820
LIG_SH3_3	94	100	PF00018	0.851
LIG_TRFH_1	122	126	PF08558	0.832
LIG_TRFH_1	177	181	PF08558	0.848
LIG_WRC_WIRS_1	119	124	PF05994	0.824
LIG_WRC_WIRS_1	65	70	PF05994	0.806
MOD_CDK_SPxxK_3	101	108	PF00069	0.850
MOD_CDK_SPxxK_3	46	53	PF00069	0.831
MOD_CK1_1	114	120	PF00069	0.820
MOD_CK1_1	206	212	PF00069	0.652
MOD_CK1_1	214	220	PF00069	0.443
MOD_CK1_1	57	63	PF00069	0.799
MOD_CK1_1	91	97	PF00069	0.841
MOD_GlcNHglycan	108	111	PF01048	0.633
MOD_GlcNHglycan	129	132	PF01048	0.644
MOD_GlcNHglycan	141	144	PF01048	0.500
MOD_GlcNHglycan	150	153	PF01048	0.537
MOD_GlcNHglycan	220	223	PF01048	0.583
MOD_GlcNHglycan	24	27	PF01048	0.628
MOD_GSK3_1	114	121	PF00069	0.822
MOD_GSK3_1	139	146	PF00069	0.854
MOD_GSK3_1	167	174	PF00069	0.854
MOD_GSK3_1	194	201	PF00069	0.583
MOD_GSK3_1	211	218	PF00069	0.270
MOD_GSK3_1	53	60	PF00069	0.825
MOD_GSK3_1	91	98	PF00069	0.843
MOD_LATS_1	31	37	PF00433	0.826
MOD_N-GLC_1	91	96	PF02516	0.638
MOD_NEK2_1	2	7	PF00069	0.817
MOD_NEK2_1	27	32	PF00069	0.813
MOD_NEK2_1	64	69	PF00069	0.799
MOD_NEK2_1	70	75	PF00069	0.763
MOD_NEK2_2	134	139	PF00069	0.852
MOD_PKA_2	143	149	PF00069	0.855
MOD_PKA_2	198	204	PF00069	0.583
MOD_PKA_2	22	28	PF00069	0.833
MOD_PKA_2	32	38	PF00069	0.702
MOD_PKA_2	52	58	PF00069	0.582
MOD_Plk_4	111	117	PF00069	0.826
MOD_Plk_4	143	149	PF00069	0.855
MOD_Plk_4	203	209	PF00069	0.652
MOD_Plk_4	3	9	PF00069	0.809
MOD_ProDKin_1	101	107	PF00069	0.662
MOD_ProDKin_1	167	173	PF00069	0.854
MOD_ProDKin_1	46	52	PF00069	0.828
MOD_ProDKin_1	54	60	PF00069	0.722
MOD_ProDKin_1	71	77	PF00069	0.624
MOD_ProDKin_1	86	92	PF00069	0.664
TRG_DiLeu_BaLyEn_6	183	188	PF01217	0.846
TRG_DiLeu_BaLyEn_6	47	52	PF01217	0.830
TRG_ENDOCYTIC_2	39	42	PF00928	0.801
TRG_ER_diArg_1	10	13	PF00400	0.801
TRG_ER_diArg_1	37	39	PF00400	0.826