Ribosomal protein L32-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein L32-like protein

Species:

Leishmania major

UniProt:

E9AF18_LEIMA

TriTrypDb:

LmjF.35.1960 , LMJLV39_350026100 , LMJSD75_350025400

Length:

211

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005829	cytosol	2	2
GO:0005840	ribosome	5	8
GO:0043226	organelle	2	8
GO:0043228	non-membrane-bounded organelle	3	8
GO:0043229	intracellular organelle	3	8
GO:0043232	intracellular non-membrane-bounded organelle	4	8
GO:0110165	cellular anatomical entity	1	8

Expansion

Sequence features

E9AF18

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AF18

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	66	70	PF00656	0.551
CLV_PCSK_KEX2_1	13	15	PF00082	0.565
CLV_PCSK_PC1ET2_1	13	15	PF00082	0.561
CLV_PCSK_SKI1_1	100	104	PF00082	0.303
CLV_PCSK_SKI1_1	200	204	PF00082	0.508
DOC_CKS1_1	188	193	PF01111	0.612
DOC_CKS1_1	26	31	PF01111	0.406
DOC_CYCLIN_yCln2_LP_2	152	158	PF00134	0.528
DOC_MAPK_gen_1	10	18	PF00069	0.492
DOC_PP2B_LxvP_1	152	155	PF13499	0.597
DOC_PP4_FxxP_1	160	163	PF00568	0.503
DOC_USP7_MATH_1	72	76	PF00917	0.552
DOC_USP7_UBL2_3	100	104	PF12436	0.597
DOC_WW_Pin1_4	187	192	PF00397	0.560
DOC_WW_Pin1_4	25	30	PF00397	0.437
LIG_14-3-3_CanoR_1	94	102	PF00244	0.581
LIG_AP2alpha_2	162	164	PF02296	0.503
LIG_BIR_III_4	201	205	PF00653	0.508
LIG_BRCT_BRCA1_1	121	125	PF00533	0.503
LIG_BRCT_BRCA1_1	87	91	PF00533	0.528
LIG_FHA_1	101	107	PF00498	0.532
LIG_FHA_1	130	136	PF00498	0.540
LIG_FHA_1	138	144	PF00498	0.511
LIG_FHA_1	201	207	PF00498	0.630
LIG_FHA_2	132	138	PF00498	0.510
LIG_FHA_2	188	194	PF00498	0.612
LIG_LIR_Gen_1	122	129	PF02991	0.496
LIG_LIR_Nem_3	122	128	PF02991	0.496
LIG_MLH1_MIPbox_1	121	125	PF16413	0.503
LIG_MYND_1	2	6	PF01753	0.484
LIG_NRBOX	101	107	PF00104	0.597
LIG_PDZ_Class_1	206	211	PF00595	0.671
LIG_Pex14_2	160	164	PF04695	0.503
LIG_SH2_STAT5	101	104	PF00017	0.528
LIG_SH2_STAT5	124	127	PF00017	0.485
LIG_SH3_3	185	191	PF00018	0.562
LIG_SH3_3	23	29	PF00018	0.558
LIG_TRAF2_1	134	137	PF00917	0.503
LIG_TRAF2_1	190	193	PF00917	0.562
MOD_CDK_SPK_2	25	30	PF00069	0.417
MOD_CK2_1	131	137	PF00069	0.503
MOD_CK2_1	187	193	PF00069	0.528
MOD_CK2_1	19	25	PF00069	0.479
MOD_GlcNHglycan	74	77	PF01048	0.368
MOD_GlcNHglycan	78	81	PF01048	0.309
MOD_GlcNHglycan	87	90	PF01048	0.325
MOD_GSK3_1	143	150	PF00069	0.578
MOD_GSK3_1	171	178	PF00069	0.599
MOD_GSK3_1	21	28	PF00069	0.389
MOD_GSK3_1	72	79	PF00069	0.532
MOD_NEK2_1	105	110	PF00069	0.597
MOD_NEK2_1	175	180	PF00069	0.599
MOD_NEK2_1	19	24	PF00069	0.542
MOD_PIKK_1	117	123	PF00454	0.591
MOD_PKA_2	93	99	PF00069	0.561
MOD_Plk_1	106	112	PF00069	0.528
MOD_Plk_4	107	113	PF00069	0.518
MOD_Plk_4	137	143	PF00069	0.505
MOD_ProDKin_1	187	193	PF00069	0.560
MOD_ProDKin_1	25	31	PF00069	0.429
TRG_ENDOCYTIC_2	124	127	PF00928	0.496

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3G1	Leptomonas seymouri	73%	100%
A0A0S4JL27	Bodo saltans	51%	93%
A0A1X0P641	Trypanosomatidae	48%	100%
A0A3Q8IHY8	Leishmania donovani	95%	100%
A4IB94	Leishmania infantum	96%	100%
E9B674	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
O05306	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	26%	100%
O06986	Bacillus subtilis (strain 168)	25%	100%
P48636	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	32%	100%