Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

E9AF14_LEIMA

TriTrypDb:

LmjF.35.1930 , LMJLV39_350025700 , LMJSD75_350025000

Length:

339

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

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Expansion

Sequence features

E9AF14

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AF14

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	22	26	PF00656	0.603
CLV_C14_Caspase3-7	74	78	PF00656	0.673
CLV_NRD_NRD_1	107	109	PF00675	0.420
CLV_NRD_NRD_1	261	263	PF00675	0.418
CLV_NRD_NRD_1	330	332	PF00675	0.607
CLV_NRD_NRD_1	46	48	PF00675	0.484
CLV_PCSK_KEX2_1	107	109	PF00082	0.457
CLV_PCSK_KEX2_1	261	263	PF00082	0.417
CLV_PCSK_KEX2_1	46	48	PF00082	0.436
CLV_PCSK_PC7_1	42	48	PF00082	0.400

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P9K1	Leptomonas seymouri	39%	100%
A0A3Q8IG78	Leishmania donovani	90%	100%
A4HML3	Leishmania braziliensis	70%	100%
A4IB90	Leishmania infantum	89%	100%
E9B670	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%

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