LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania major
UniProt:
E9AEV8_LEIMA
TriTrypDb:
LmjF.35.1355 , LMJLV39_350019900 * , LMJSD75_350019100
Length:
329

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AEV8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AEV8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 201 205 PF00656 0.633
CLV_NRD_NRD_1 258 260 PF00675 0.571
CLV_NRD_NRD_1 51 53 PF00675 0.627
CLV_PCSK_KEX2_1 258 260 PF00082 0.571
CLV_PCSK_KEX2_1 51 53 PF00082 0.627
CLV_PCSK_PC7_1 47 53 PF00082 0.615
CLV_PCSK_SKI1_1 286 290 PF00082 0.694
DEG_COP1_1 168 176 PF00400 0.542
DEG_COP1_1 58 68 PF00400 0.565
DEG_SPOP_SBC_1 226 230 PF00917 0.556
DEG_SPOP_SBC_1 81 85 PF00917 0.541
DOC_CKS1_1 173 178 PF01111 0.556
DOC_CKS1_1 191 196 PF01111 0.643
DOC_MAPK_RevD_3 244 259 PF00069 0.564
DOC_PP2B_LxvP_1 135 138 PF13499 0.675
DOC_PP2B_LxvP_1 253 256 PF13499 0.560
DOC_USP7_MATH_1 106 110 PF00917 0.618
DOC_USP7_MATH_1 125 129 PF00917 0.572
DOC_USP7_MATH_1 197 201 PF00917 0.597
DOC_USP7_MATH_1 226 230 PF00917 0.699
DOC_USP7_MATH_1 232 236 PF00917 0.751
DOC_USP7_MATH_1 284 288 PF00917 0.646
DOC_USP7_MATH_1 60 64 PF00917 0.610
DOC_USP7_MATH_1 68 72 PF00917 0.639
DOC_USP7_MATH_1 81 85 PF00917 0.576
DOC_WW_Pin1_4 12 17 PF00397 0.638
DOC_WW_Pin1_4 168 173 PF00397 0.790
DOC_WW_Pin1_4 187 192 PF00397 0.644
DOC_WW_Pin1_4 309 314 PF00397 0.609
LIG_14-3-3_CanoR_1 123 130 PF00244 0.609
LIG_14-3-3_CanoR_1 286 295 PF00244 0.675
LIG_14-3-3_CanoR_1 56 65 PF00244 0.568
LIG_14-3-3_CanoR_1 72 81 PF00244 0.710
LIG_BIR_II_1 1 5 PF00653 0.601
LIG_BRCT_BRCA1_1 198 202 PF00533 0.671
LIG_DLG_GKlike_1 163 171 PF00625 0.555
LIG_FHA_2 160 166 PF00498 0.647
LIG_FHA_2 191 197 PF00498 0.640
LIG_FHA_2 209 215 PF00498 0.625
LIG_LIR_Gen_1 27 36 PF02991 0.573
LIG_LIR_Nem_3 251 257 PF02991 0.562
LIG_LIR_Nem_3 27 31 PF02991 0.664
LIG_MYND_1 215 219 PF01753 0.655
LIG_SH2_PTP2 254 257 PF00017 0.559
LIG_SH2_STAT5 254 257 PF00017 0.568
LIG_SH3_3 170 176 PF00018 0.689
LIG_SH3_3 188 194 PF00018 0.644
LIG_SH3_3 243 249 PF00018 0.568
MOD_CDK_SPK_2 187 192 PF00069 0.625
MOD_CDK_SPxK_1 172 178 PF00069 0.540
MOD_CK1_1 128 134 PF00069 0.655
MOD_CK1_1 15 21 PF00069 0.754
MOD_CK1_1 200 206 PF00069 0.708
MOD_CK1_1 220 226 PF00069 0.587
MOD_CK1_1 312 318 PF00069 0.594
MOD_CK1_1 4 10 PF00069 0.576
MOD_CK1_1 55 61 PF00069 0.766
MOD_CK1_1 71 77 PF00069 0.741
MOD_CK1_1 83 89 PF00069 0.521
MOD_CK2_1 159 165 PF00069 0.679
MOD_CK2_1 270 276 PF00069 0.620
MOD_CK2_1 284 290 PF00069 0.685
MOD_GlcNHglycan 117 120 PF01048 0.680
MOD_GlcNHglycan 152 155 PF01048 0.697
MOD_GlcNHglycan 239 242 PF01048 0.625
MOD_GlcNHglycan 286 289 PF01048 0.624
MOD_GlcNHglycan 322 325 PF01048 0.657
MOD_GlcNHglycan 58 61 PF01048 0.731
MOD_GlcNHglycan 62 65 PF01048 0.628
MOD_GlcNHglycan 66 69 PF01048 0.486
MOD_GlcNHglycan 7 10 PF01048 0.743
MOD_GlcNHglycan 76 79 PF01048 0.572
MOD_GSK3_1 1 8 PF00069 0.577
MOD_GSK3_1 115 122 PF00069 0.541
MOD_GSK3_1 159 166 PF00069 0.682
MOD_GSK3_1 168 175 PF00069 0.608
MOD_GSK3_1 196 203 PF00069 0.762
MOD_GSK3_1 209 216 PF00069 0.654
MOD_GSK3_1 314 321 PF00069 0.667
MOD_GSK3_1 42 49 PF00069 0.647
MOD_GSK3_1 51 58 PF00069 0.676
MOD_GSK3_1 60 67 PF00069 0.594
MOD_GSK3_1 68 75 PF00069 0.736
MOD_N-GLC_1 68 73 PF02516 0.559
MOD_NEK2_1 1 6 PF00069 0.627
MOD_NEK2_1 112 117 PF00069 0.762
MOD_NEK2_1 167 172 PF00069 0.595
MOD_NEK2_1 202 207 PF00069 0.815
MOD_NEK2_1 237 242 PF00069 0.642
MOD_NEK2_1 275 280 PF00069 0.709
MOD_PIKK_1 123 129 PF00454 0.609
MOD_PKA_1 51 57 PF00069 0.625
MOD_PKA_2 112 118 PF00069 0.614
MOD_PKA_2 197 203 PF00069 0.628
MOD_PKA_2 318 324 PF00069 0.639
MOD_PKA_2 46 52 PF00069 0.644
MOD_PKA_2 55 61 PF00069 0.546
MOD_PKA_2 71 77 PF00069 0.694
MOD_PKB_1 139 147 PF00069 0.657
MOD_PKB_1 178 186 PF00069 0.552
MOD_Plk_1 203 209 PF00069 0.611
MOD_Plk_1 68 74 PF00069 0.561
MOD_Plk_4 125 131 PF00069 0.596
MOD_Plk_4 15 21 PF00069 0.622
MOD_Plk_4 217 223 PF00069 0.664
MOD_ProDKin_1 12 18 PF00069 0.637
MOD_ProDKin_1 168 174 PF00069 0.786
MOD_ProDKin_1 187 193 PF00069 0.643
MOD_ProDKin_1 309 315 PF00069 0.608
MOD_SUMO_rev_2 144 148 PF00179 0.623
TRG_ENDOCYTIC_2 254 257 PF00928 0.559
TRG_ER_diArg_1 138 141 PF00400 0.586
TRG_ER_diArg_1 257 259 PF00400 0.566

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I411 Leptomonas seymouri 32% 88%
A0A3S7X926 Leishmania donovani 90% 100%
A4HMF7 Leishmania braziliensis 65% 99%
E9AHU5 Leishmania infantum 90% 100%
E9B614 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS