A large and likely artifical grouping of protease domain carrying proteins related to proteasomal proteases. Only a tiny subgroup (the AFG3-related mitochondrail proteins) seem to have a TM segment.. Localization: Cytoplasmic (by homology) / Mitochondrial (by homology)
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 25 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 16 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 9 |
| NetGPI | no | yes: 0, no: 9 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005741 | mitochondrial outer membrane | 5 | 2 |
| GO:0016020 | membrane | 2 | 3 |
| GO:0019867 | outer membrane | 3 | 2 |
| GO:0031090 | organelle membrane | 3 | 2 |
| GO:0031966 | mitochondrial membrane | 4 | 2 |
| GO:0031968 | organelle outer membrane | 4 | 2 |
| GO:0098588 | bounding membrane of organelle | 4 | 2 |
| GO:0110165 | cellular anatomical entity | 1 | 3 |
Related structures:
AlphaFold database: E9AEU9
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000166 | nucleotide binding | 3 | 10 |
| GO:0003824 | catalytic activity | 1 | 10 |
| GO:0005488 | binding | 1 | 10 |
| GO:0005524 | ATP binding | 5 | 10 |
| GO:0016462 | pyrophosphatase activity | 5 | 10 |
| GO:0016787 | hydrolase activity | 2 | 10 |
| GO:0016817 | hydrolase activity, acting on acid anhydrides | 3 | 10 |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 4 | 10 |
| GO:0016887 | ATP hydrolysis activity | 7 | 10 |
| GO:0017076 | purine nucleotide binding | 4 | 10 |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 6 | 10 |
| GO:0030554 | adenyl nucleotide binding | 5 | 10 |
| GO:0032553 | ribonucleotide binding | 3 | 10 |
| GO:0032555 | purine ribonucleotide binding | 4 | 10 |
| GO:0032559 | adenyl ribonucleotide binding | 5 | 10 |
| GO:0035639 | purine ribonucleoside triphosphate binding | 4 | 10 |
| GO:0036094 | small molecule binding | 2 | 10 |
| GO:0043167 | ion binding | 2 | 10 |
| GO:0043168 | anion binding | 3 | 10 |
| GO:0097159 | organic cyclic compound binding | 2 | 10 |
| GO:0097367 | carbohydrate derivative binding | 2 | 10 |
| GO:1901265 | nucleoside phosphate binding | 3 | 10 |
| GO:1901363 | heterocyclic compound binding | 2 | 10 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 107 | 111 | PF00656 | 0.560 |
| CLV_C14_Caspase3-7 | 201 | 205 | PF00656 | 0.452 |
| CLV_C14_Caspase3-7 | 211 | 215 | PF00656 | 0.452 |
| CLV_MEL_PAP_1 | 18 | 24 | PF00089 | 0.633 |
| CLV_NRD_NRD_1 | 248 | 250 | PF00675 | 0.281 |
| CLV_NRD_NRD_1 | 258 | 260 | PF00675 | 0.222 |
| CLV_NRD_NRD_1 | 67 | 69 | PF00675 | 0.454 |
| CLV_PCSK_KEX2_1 | 248 | 250 | PF00082 | 0.277 |
| CLV_PCSK_KEX2_1 | 257 | 259 | PF00082 | 0.226 |
| CLV_PCSK_KEX2_1 | 67 | 69 | PF00082 | 0.478 |
| CLV_PCSK_SKI1_1 | 109 | 113 | PF00082 | 0.305 |
| CLV_PCSK_SKI1_1 | 136 | 140 | PF00082 | 0.262 |
| CLV_PCSK_SKI1_1 | 148 | 152 | PF00082 | 0.263 |
| CLV_PCSK_SKI1_1 | 222 | 226 | PF00082 | 0.258 |
| CLV_PCSK_SKI1_1 | 24 | 28 | PF00082 | 0.615 |
| CLV_PCSK_SKI1_1 | 248 | 252 | PF00082 | 0.335 |
| CLV_PCSK_SKI1_1 | 56 | 60 | PF00082 | 0.382 |
| CLV_PCSK_SKI1_1 | 67 | 71 | PF00082 | 0.406 |
| DEG_APCC_DBOX_1 | 23 | 31 | PF00400 | 0.442 |
| DEG_MDM2_SWIB_1 | 225 | 232 | PF02201 | 0.452 |
| DOC_CYCLIN_RxL_1 | 255 | 265 | PF00134 | 0.452 |
| DOC_MAPK_gen_1 | 257 | 266 | PF00069 | 0.452 |
| DOC_MAPK_gen_1 | 272 | 280 | PF00069 | 0.507 |
| DOC_MAPK_gen_1 | 61 | 71 | PF00069 | 0.652 |
| DOC_MAPK_MEF2A_6 | 192 | 199 | PF00069 | 0.452 |
| DOC_MAPK_MEF2A_6 | 257 | 266 | PF00069 | 0.465 |
| DOC_MAPK_MEF2A_6 | 274 | 282 | PF00069 | 0.502 |
| DOC_MAPK_NFAT4_5 | 257 | 265 | PF00069 | 0.452 |
| DOC_PP2B_LxvP_1 | 264 | 267 | PF13499 | 0.495 |
| DOC_SPAK_OSR1_1 | 249 | 253 | PF12202 | 0.535 |
| DOC_USP7_UBL2_3 | 272 | 276 | PF12436 | 0.596 |
| DOC_WW_Pin1_4 | 191 | 196 | PF00397 | 0.469 |
| DOC_WW_Pin1_4 | 213 | 218 | PF00397 | 0.496 |
| DOC_WW_Pin1_4 | 37 | 42 | PF00397 | 0.313 |
| LIG_14-3-3_CanoR_1 | 21 | 27 | PF00244 | 0.463 |
| LIG_14-3-3_CanoR_1 | 67 | 72 | PF00244 | 0.620 |
| LIG_14-3-3_CterR_2 | 356 | 361 | PF00244 | 0.607 |
| LIG_Actin_WH2_2 | 19 | 36 | PF00022 | 0.412 |
| LIG_BIR_III_2 | 214 | 218 | PF00653 | 0.469 |
| LIG_DCNL_PONY_1 | 1 | 4 | PF03556 | 0.491 |
| LIG_FHA_1 | 111 | 117 | PF00498 | 0.584 |
| LIG_FHA_1 | 166 | 172 | PF00498 | 0.470 |
| LIG_FHA_1 | 53 | 59 | PF00498 | 0.496 |
| LIG_FHA_1 | 64 | 70 | PF00498 | 0.644 |
| LIG_FHA_1 | 9 | 15 | PF00498 | 0.530 |
| LIG_FHA_2 | 225 | 231 | PF00498 | 0.464 |
| LIG_FHA_2 | 249 | 255 | PF00498 | 0.535 |
| LIG_FHA_2 | 305 | 311 | PF00498 | 0.452 |
| LIG_GBD_Chelix_1 | 151 | 159 | PF00786 | 0.269 |
| LIG_LIR_Gen_1 | 162 | 171 | PF02991 | 0.503 |
| LIG_LIR_Gen_1 | 96 | 105 | PF02991 | 0.545 |
| LIG_LIR_Nem_3 | 162 | 166 | PF02991 | 0.503 |
| LIG_LIR_Nem_3 | 227 | 232 | PF02991 | 0.452 |
| LIG_LIR_Nem_3 | 40 | 46 | PF02991 | 0.350 |
| LIG_LIR_Nem_3 | 96 | 102 | PF02991 | 0.550 |
| LIG_NRBOX | 277 | 283 | PF00104 | 0.519 |
| LIG_Pex14_2 | 225 | 229 | PF04695 | 0.452 |
| LIG_SH2_CRK | 141 | 145 | PF00017 | 0.452 |
| LIG_SH2_PTP2 | 298 | 301 | PF00017 | 0.535 |
| LIG_SH2_STAT5 | 298 | 301 | PF00017 | 0.484 |
| LIG_SH2_STAT5 | 306 | 309 | PF00017 | 0.476 |
| LIG_SH2_STAT5 | 43 | 46 | PF00017 | 0.298 |
| LIG_SH2_STAT5 | 47 | 50 | PF00017 | 0.280 |
| LIG_SH3_3 | 263 | 269 | PF00018 | 0.460 |
| LIG_SUMO_SIM_par_1 | 87 | 93 | PF11976 | 0.579 |
| LIG_TYR_ITIM | 296 | 301 | PF00017 | 0.535 |
| MOD_CK1_1 | 127 | 133 | PF00069 | 0.627 |
| MOD_CK1_1 | 170 | 176 | PF00069 | 0.452 |
| MOD_CK1_1 | 205 | 211 | PF00069 | 0.501 |
| MOD_CK1_1 | 309 | 315 | PF00069 | 0.474 |
| MOD_CK1_1 | 63 | 69 | PF00069 | 0.683 |
| MOD_CK2_1 | 25 | 31 | PF00069 | 0.330 |
| MOD_GlcNHglycan | 126 | 129 | PF01048 | 0.420 |
| MOD_GlcNHglycan | 210 | 213 | PF01048 | 0.335 |
| MOD_GlcNHglycan | 335 | 338 | PF01048 | 0.522 |
| MOD_GSK3_1 | 202 | 209 | PF00069 | 0.535 |
| MOD_GSK3_1 | 220 | 227 | PF00069 | 0.437 |
| MOD_GSK3_1 | 300 | 307 | PF00069 | 0.452 |
| MOD_GSK3_1 | 33 | 40 | PF00069 | 0.414 |
| MOD_GSK3_1 | 52 | 59 | PF00069 | 0.500 |
| MOD_GSK3_1 | 63 | 70 | PF00069 | 0.640 |
| MOD_N-GLC_1 | 59 | 64 | PF02516 | 0.484 |
| MOD_NEK2_1 | 159 | 164 | PF00069 | 0.495 |
| MOD_NEK2_1 | 206 | 211 | PF00069 | 0.522 |
| MOD_NEK2_1 | 33 | 38 | PF00069 | 0.485 |
| MOD_PIKK_1 | 343 | 349 | PF00454 | 0.629 |
| MOD_PK_1 | 276 | 282 | PF00069 | 0.585 |
| MOD_PKA_1 | 248 | 254 | PF00069 | 0.535 |
| MOD_PKA_1 | 67 | 73 | PF00069 | 0.623 |
| MOD_PKA_2 | 248 | 254 | PF00069 | 0.535 |
| MOD_PKA_2 | 60 | 66 | PF00069 | 0.679 |
| MOD_PKA_2 | 67 | 73 | PF00069 | 0.627 |
| MOD_Plk_4 | 146 | 152 | PF00069 | 0.455 |
| MOD_Plk_4 | 159 | 165 | PF00069 | 0.520 |
| MOD_Plk_4 | 167 | 173 | PF00069 | 0.460 |
| MOD_Plk_4 | 202 | 208 | PF00069 | 0.514 |
| MOD_Plk_4 | 220 | 226 | PF00069 | 0.390 |
| MOD_Plk_4 | 25 | 31 | PF00069 | 0.412 |
| MOD_Plk_4 | 276 | 282 | PF00069 | 0.545 |
| MOD_ProDKin_1 | 191 | 197 | PF00069 | 0.469 |
| MOD_ProDKin_1 | 213 | 219 | PF00069 | 0.496 |
| MOD_ProDKin_1 | 37 | 43 | PF00069 | 0.313 |
| MOD_SUMO_rev_2 | 101 | 111 | PF00179 | 0.504 |
| MOD_SUMO_rev_2 | 265 | 273 | PF00179 | 0.594 |
| TRG_DiLeu_BaEn_1 | 202 | 207 | PF01217 | 0.452 |
| TRG_ENDOCYTIC_2 | 298 | 301 | PF00928 | 0.550 |
| TRG_ENDOCYTIC_2 | 43 | 46 | PF00928 | 0.298 |
| TRG_ER_diArg_1 | 248 | 250 | PF00400 | 0.479 |
| TRG_ER_diArg_1 | 256 | 259 | PF00400 | 0.430 |
| TRG_ER_diArg_1 | 67 | 69 | PF00400 | 0.678 |
| TRG_Pf-PMV_PEXEL_1 | 153 | 158 | PF00026 | 0.269 |
| TRG_Pf-PMV_PEXEL_1 | 258 | 263 | PF00026 | 0.276 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P5V2 | Leptomonas seymouri | 83% | 100% |
| A0A0N0P643 | Leptomonas seymouri | 31% | 67% |
| A0A0N1HRH8 | Leptomonas seymouri | 32% | 66% |
| A0A0N1IM81 | Leptomonas seymouri | 33% | 82% |
| A0A0N1P9H6 | Leptomonas seymouri | 33% | 81% |
| A0A0S4IPV5 | Bodo saltans | 34% | 82% |
| A0A0S4IY28 | Bodo saltans | 35% | 100% |
| A0A0S4JKQ6 | Bodo saltans | 26% | 100% |
| A0A0S4JSD8 | Bodo saltans | 33% | 91% |
| A0A0S4KLG9 | Bodo saltans | 37% | 72% |
| A0A1X0NHF1 | Trypanosomatidae | 58% | 100% |
| A0A1X0NMZ3 | Trypanosomatidae | 32% | 83% |
| A0A1X0P983 | Trypanosomatidae | 36% | 81% |
| A0A3Q8IHU1 | Leishmania donovani | 98% | 100% |
| A0A3R7KBD2 | Trypanosoma rangeli | 58% | 100% |
| A0A3R7KPY1 | Trypanosoma rangeli | 32% | 80% |
| A0A3S7WSK7 | Leishmania donovani | 33% | 82% |
| A0A3S7X163 | Leishmania donovani | 33% | 68% |
| A0A3S7X2R4 | Leishmania donovani | 34% | 81% |
| A0JMA9 | Xenopus tropicalis | 34% | 67% |
| A4H795 | Leishmania braziliensis | 33% | 83% |
| A4HG81 | Leishmania braziliensis | 34% | 69% |
| A4HME8 | Leishmania braziliensis | 94% | 100% |
| A4HVN7 | Leishmania infantum | 33% | 82% |
| A4I4W4 | Leishmania infantum | 34% | 81% |
| A4IB20 | Leishmania infantum | 98% | 100% |
| A7I8B8 | Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8) | 33% | 83% |
| A8QFF6 | Brugia malayi | 39% | 80% |
| A8XV40 | Caenorhabditis briggsae | 40% | 67% |
| A9RA82 | Papio anubis | 34% | 74% |
| B0K657 | Thermoanaerobacter sp. (strain X514) | 32% | 71% |
| B3EX35 | Sorex araneus | 34% | 74% |
| B4F6J6 | Xenopus tropicalis | 40% | 100% |
| B4USW8 | Otolemur garnettii | 34% | 74% |
| B5X3X5 | Salmo salar | 33% | 74% |
| B6YXR2 | Thermococcus onnurineus (strain NA1) | 35% | 91% |
| B7NZ88 | Oryctolagus cuniculus | 34% | 74% |
| C3PGA0 | Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CIP 107346 / CN-1) | 33% | 69% |
| C5A6P8 | Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) | 33% | 91% |
| C9ZKZ7 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 36% | 81% |
| C9ZLZ3 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 36% | 78% |
| C9ZNL6 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 57% | 100% |
| C9ZRM8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 31% | 81% |
| D0A6K9 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 33% | 83% |
| D0FH76 | Bombyx mori | 37% | 82% |
| D1C4U5 | Sphaerobacter thermophilus (strain DSM 20745 / S 6022) | 32% | 74% |
| E9AEB2 | Leishmania major | 34% | 81% |
| E9ALH4 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 34% | 81% |
| E9APD3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 33% | 82% |
| E9AZK1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 32% | 67% |
| E9B605 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 98% | 100% |
| F2Z6D2 | Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) | 36% | 97% |
| F6QV99 | Bos taurus | 41% | 100% |
| O26824 | Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) | 35% | 88% |
| O57940 | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) | 34% | 90% |
| O74894 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 29% | 93% |
| O75351 | Homo sapiens | 36% | 81% |
| O75449 | Homo sapiens | 34% | 74% |
| P28737 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 43% | 100% |
| P34124 | Dictyostelium discoideum | 35% | 90% |
| P34808 | Caenorhabditis elegans | 36% | 76% |
| P36612 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 32% | 81% |
| P40327 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 29% | 83% |
| P41836 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 37% | 90% |
| P43686 | Homo sapiens | 32% | 86% |
| P46467 | Mus musculus | 36% | 81% |
| P46502 | Caenorhabditis elegans | 31% | 87% |
| P46507 | Manduca sexta | 33% | 87% |
| P52917 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 35% | 83% |
| P53549 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 32% | 83% |
| P54775 | Mus musculus | 32% | 86% |
| P54815 | Caenorhabditis elegans | 39% | 100% |
| P62333 | Homo sapiens | 35% | 93% |
| P62334 | Mus musculus | 35% | 93% |
| P62335 | Ictidomys tridecemlineatus | 35% | 93% |
| Q01939 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 33% | 89% |
| Q0IIR9 | Xenopus tropicalis | 33% | 73% |
| Q0VD48 | Bos taurus | 36% | 81% |
| Q18787 | Caenorhabditis elegans | 35% | 83% |
| Q1HGK7 | Gallus gallus | 34% | 73% |
| Q25544 | Naegleria fowleri | 33% | 87% |
| Q2FQ56 | Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) | 33% | 88% |
| Q2KIW6 | Bos taurus | 35% | 93% |
| Q3B8D5 | Xenopus laevis | 30% | 71% |
| Q3T030 | Bos taurus | 32% | 86% |
| Q4QG45 | Leishmania major | 33% | 82% |
| Q4R407 | Macaca fascicularis | 34% | 74% |
| Q4R7L3 | Macaca fascicularis | 32% | 86% |
| Q503W7 | Danio rerio | 38% | 100% |
| Q505J9 | Rattus norvegicus | 41% | 100% |
| Q54PN7 | Dictyostelium discoideum | 33% | 86% |
| Q54PT2 | Dictyostelium discoideum | 36% | 81% |
| Q55BV5 | Dictyostelium discoideum | 31% | 82% |
| Q58576 | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | 33% | 84% |
| Q5JHS5 | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | 34% | 91% |
| Q5R658 | Pongo abelii | 36% | 81% |
| Q5RII9 | Danio rerio | 33% | 74% |
| Q5U3S1 | Danio rerio | 32% | 74% |
| Q5UT56 | Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) | 34% | 88% |
| Q5XIK7 | Rattus norvegicus | 35% | 74% |
| Q63570 | Rattus norvegicus | 32% | 86% |
| Q6E0V2 | Rattus norvegicus | 34% | 74% |
| Q793F9 | Rattus norvegicus | 36% | 83% |
| Q7ZZ25 | Danio rerio | 42% | 95% |
| Q8IYT4 | Homo sapiens | 32% | 67% |
| Q8K0T4 | Mus musculus | 35% | 74% |
| Q8MNV0 | Caenorhabditis elegans | 36% | 71% |
| Q8NBU5 | Homo sapiens | 41% | 100% |
| Q8PY58 | Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) | 34% | 86% |
| Q8SQI9 | Encephalitozoon cuniculi (strain GB-M1) | 29% | 93% |
| Q8SRH0 | Encephalitozoon cuniculi (strain GB-M1) | 29% | 85% |
| Q8TI88 | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) | 34% | 86% |
| Q8U4H3 | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | 32% | 91% |
| Q8VEJ9 | Mus musculus | 36% | 83% |
| Q94BQ2 | Arabidopsis thaliana | 35% | 86% |
| Q9BW62 | Homo sapiens | 34% | 74% |
| Q9C5U3 | Arabidopsis thaliana | 35% | 86% |
| Q9D3R6 | Mus musculus | 32% | 67% |
| Q9D5T0 | Mus musculus | 41% | 100% |
| Q9HRW6 | Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) | 33% | 89% |
| Q9MAK9 | Arabidopsis thaliana | 35% | 90% |
| Q9P7J5 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 41% | 100% |
| Q9PUL2 | Xenopus laevis | 33% | 74% |
| Q9SEI3 | Arabidopsis thaliana | 36% | 90% |
| Q9SEI4 | Arabidopsis thaliana | 30% | 88% |
| Q9UN37 | Homo sapiens | 36% | 83% |
| Q9V287 | Pyrococcus abyssi (strain GE5 / Orsay) | 34% | 91% |
| Q9VQN8 | Drosophila melanogaster | 39% | 69% |
| Q9WV86 | Mus musculus | 35% | 74% |
| Q9YAC7 | Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) | 31% | 88% |
| Q9ZNT0 | Arabidopsis thaliana | 32% | 83% |
| V5BCC9 | Trypanosoma cruzi | 40% | 100% |