Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AER9_LEIMA

TriTrypDb:

LmjF.35.0940 , LMJLV39_350015200 , LMJSD75_350014800

Length:

163


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

E9AER9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AER9


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	131	133	PF00675	0.353
CLV_NRD_NRD_1	153	155	PF00675	0.598
CLV_PCSK_KEX2_1	130	132	PF00082	0.347
CLV_PCSK_KEX2_1	153	155	PF00082	0.534
CLV_PCSK_PC1ET2_1	130	132	PF00082	0.393
CLV_PCSK_SKI1_1	108	112	PF00082	0.420
DOC_USP7_MATH_2	5	11	PF00917	0.723
DOC_USP7_UBL2_3	108	112	PF12436	0.646
DOC_USP7_UBL2_3	19	23	PF12436	0.694
DOC_WW_Pin1_4	81	86	PF00397	0.642
DOC_WW_Pin1_4	89	94	PF00397	0.654
LIG_14-3-3_CanoR_1	72	78	PF00244	0.632
LIG_BRCT_BRCA1_1	9	13	PF00533	0.664
LIG_FHA_1	19	25	PF00498	0.686
LIG_FHA_2	111	117	PF00498	0.610
LIG_FHA_2	124	130	PF00498	0.431
LIG_LIR_Gen_1	14	24	PF02991	0.623
LIG_LIR_Nem_3	14	20	PF02991	0.630
LIG_LYPXL_yS_3	122	125	PF13949	0.665
LIG_MAD2	109	117	PF02301	0.686
LIG_Pex14_2	13	17	PF04695	0.638
LIG_SH2_NCK_1	41	45	PF00017	0.726
LIG_SH2_STAP1	106	110	PF00017	0.670
LIG_SH2_STAT5	77	80	PF00017	0.638
LIG_SH3_3	87	93	PF00018	0.667
LIG_SUMO_SIM_par_1	123	129	PF11976	0.667
LIG_TRAF2_1	126	129	PF00917	0.629
LIG_ULM_U2AF65_1	130	136	PF00076	0.648
MOD_CDK_SPxxK_3	89	96	PF00069	0.652
MOD_CK1_1	76	82	PF00069	0.639
MOD_CK2_1	110	116	PF00069	0.614
MOD_CK2_1	123	129	PF00069	0.438
MOD_GlcNHglycan	141	144	PF01048	0.453
MOD_GlcNHglycan	9	12	PF01048	0.447
MOD_NEK2_1	147	152	PF00069	0.445
MOD_Plk_1	13	19	PF00069	0.634
MOD_ProDKin_1	81	87	PF00069	0.640
MOD_ProDKin_1	89	95	PF00069	0.654
MOD_SUMO_rev_2	92	98	PF00179	0.657
TRG_ENDOCYTIC_2	121	124	PF00928	0.642
TRG_ER_diArg_1	131	133	PF00400	0.552
TRG_ER_diArg_1	152	154	PF00400	0.598
TRG_Pf-PMV_PEXEL_1	153	157	PF00026	0.659


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIS0	Leptomonas seymouri	73%	72%
A0A0S4IWD5	Bodo saltans	36%	93%
A0A1X0NKL7	Trypanosomatidae	53%	87%
C9ZNI9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	75%
E9B5X4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	69%