CX9C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

MICOS complex subunit MIC17, putative

Species:

Leishmania major

UniProt:

E9AER4_LEIMA

TriTrypDb:

LmjF.35.0890 , LMJLV39_350014600 , LMJSD75_350014100

Length:

165


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0031974	membrane-enclosed lumen	2	2
GO:0031981	nuclear lumen	5	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0043233	organelle lumen	3	2
GO:0070013	intracellular organelle lumen	4	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	2

E9AER4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AER4


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	100	104	PF00082	0.509
DEG_Nend_Nbox_1	1	3	PF02207	0.768
DEG_SPOP_SBC_1	77	81	PF00917	0.698
DEG_SPOP_SBC_1	83	87	PF00917	0.750
DOC_CYCLIN_yCln2_LP_2	47	53	PF00134	0.545
DOC_PP2B_LxvP_1	111	114	PF13499	0.592
DOC_USP7_MATH_1	153	157	PF00917	0.537
DOC_USP7_MATH_1	24	28	PF00917	0.579
DOC_USP7_MATH_1	83	87	PF00917	0.735
DOC_USP7_UBL2_3	159	163	PF12436	0.641
DOC_USP7_UBL2_3	6	10	PF12436	0.684
DOC_WW_Pin1_4	4	9	PF00397	0.680
DOC_WW_Pin1_4	46	51	PF00397	0.536
DOC_WW_Pin1_4	85	90	PF00397	0.763
LIG_LIR_Gen_1	108	115	PF02991	0.601
LIG_LIR_Nem_3	108	113	PF02991	0.534
LIG_LIR_Nem_3	27	32	PF02991	0.480
LIG_SH2_CRK	69	73	PF00017	0.569
LIG_SH2_STAP1	119	123	PF00017	0.426
LIG_SH3_3	86	92	PF00018	0.782
MOD_CDK_SPxK_1	4	10	PF00069	0.644
MOD_CK1_1	35	41	PF00069	0.598
MOD_CK1_1	4	10	PF00069	0.741
MOD_CK1_1	76	82	PF00069	0.710
MOD_CK1_1	85	91	PF00069	0.690
MOD_GlcNHglycan	100	103	PF01048	0.602
MOD_GlcNHglycan	155	158	PF01048	0.476
MOD_GlcNHglycan	75	78	PF01048	0.610
MOD_GSK3_1	72	79	PF00069	0.583
MOD_GSK3_1	94	101	PF00069	0.707
MOD_N-GLC_1	35	40	PF02516	0.474
MOD_NEK2_1	1	6	PF00069	0.763
MOD_NEK2_1	51	56	PF00069	0.552
MOD_NEK2_1	72	77	PF00069	0.572
MOD_PIKK_1	145	151	PF00454	0.536
MOD_Plk_1	129	135	PF00069	0.463
MOD_Plk_1	35	41	PF00069	0.492
MOD_Plk_4	35	41	PF00069	0.601
MOD_ProDKin_1	4	10	PF00069	0.683
MOD_ProDKin_1	46	52	PF00069	0.540
MOD_ProDKin_1	85	91	PF00069	0.761
MOD_SUMO_rev_2	27	32	PF00179	0.588
MOD_SUMO_rev_2	97	102	PF00179	0.750
TRG_ENDOCYTIC_2	69	72	PF00928	0.563


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3P8	Leptomonas seymouri	63%	93%
A0A1X0NIU2	Trypanosomatidae	35%	100%
A0A3R7KNC4	Trypanosoma rangeli	35%	96%
A0A3S7X8W7	Leishmania donovani	94%	100%
A4HMC0	Leishmania braziliensis	81%	100%
A4IAY6	Leishmania infantum	93%	100%
C9ZNI3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
E9B5W9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
V5D1X1	Trypanosoma cruzi	36%	99%