LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
E9AEP0_LEIMA
TriTrypDb:
Length:
57

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AEP0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AEP0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 52 56 PF00082 0.724
DEG_Nend_UBRbox_1 1 4 PF02207 0.774
DOC_CYCLIN_yClb3_PxF_3 42 48 PF00134 0.696
DOC_PP4_FxxP_1 39 42 PF00568 0.717
DOC_PP4_FxxP_1 9 12 PF00568 0.749
DOC_WW_Pin1_4 38 43 PF00397 0.715
DOC_WW_Pin1_4 7 12 PF00397 0.747
LIG_14-3-3_CanoR_1 17 24 PF00244 0.781
LIG_APCC_ABBA_1 31 36 PF00400 0.751
LIG_FHA_1 19 25 PF00498 0.780
LIG_LIR_Apic_2 36 42 PF02991 0.728
LIG_LIR_Apic_2 7 12 PF02991 0.747
LIG_LIR_Nem_3 50 54 PF02991 0.718
LIG_MYND_1 11 15 PF01753 0.750
LIG_PDZ_Class_2 52 57 PF00595 0.730
LIG_SH3_2 12 17 PF14604 0.756
LIG_SH3_3 40 46 PF00018 0.702
LIG_SH3_3 9 15 PF00018 0.749
LIG_TRAF2_1 27 30 PF00917 0.768
LIG_WRC_WIRS_1 48 53 PF05994 0.711
LIG_WW_2 43 46 PF00397 0.695
MOD_CK1_1 50 56 PF00069 0.720
MOD_CK1_1 7 13 PF00069 0.748
MOD_CK2_1 24 30 PF00069 0.770
MOD_GSK3_1 18 25 PF00069 0.779
MOD_NEK2_1 1 6 PF00069 0.765
MOD_NEK2_1 18 23 PF00069 0.483
MOD_NEK2_1 47 52 PF00069 0.707
MOD_PIKK_1 24 30 PF00454 0.770
MOD_PKA_1 22 28 PF00069 0.776
MOD_PKA_2 16 22 PF00069 0.777
MOD_Plk_4 4 10 PF00069 0.748
MOD_ProDKin_1 38 44 PF00069 0.713
MOD_ProDKin_1 7 13 PF00069 0.748
TRG_DiLeu_BaLyEn_6 9 14 PF01217 0.748

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS