LeishMANIAdb
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Copper transporter

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Copper transporter
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
E9AEM5_LEIMA
TriTrypDb:
LmjF.35.0480 , LMJLV39_350010200 , LMJSD75_350010100
Length:
138

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Cellular components
Term Name Level Count
GO:0016020 membrane 2 3
GO:0110165 cellular anatomical entity 1 3

Expansion

Sequence features

E9AEM5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AEM5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 43 45 PF00675 0.443
CLV_NRD_NRD_1 48 50 PF00675 0.444
CLV_PCSK_KEX2_1 42 44 PF00082 0.444
CLV_PCSK_KEX2_1 47 49 PF00082 0.495
CLV_PCSK_PC7_1 43 49 PF00082 0.404
DEG_Nend_Nbox_1 1 3 PF02207 0.461
DEG_SPOP_SBC_1 62 66 PF00917 0.709
DOC_MAPK_RevD_3 27 43 PF00069 0.399
DOC_USP7_MATH_1 23 27 PF00917 0.399
DOC_USP7_MATH_1 62 66 PF00917 0.773
LIG_APCC_ABBAyCdc20_2 7 13 PF00400 0.388
LIG_BRCT_BRCA1_1 121 125 PF00533 0.399
LIG_DCNL_PONY_1 1 4 PF03556 0.456
LIG_EH1_1 124 132 PF00400 0.399
LIG_FHA_1 111 117 PF00498 0.253
LIG_FHA_1 94 100 PF00498 0.324
LIG_FHA_2 51 57 PF00498 0.757
LIG_FHA_2 99 105 PF00498 0.399
LIG_IBAR_NPY_1 74 76 PF08397 0.635
LIG_LIR_Gen_1 122 131 PF02991 0.399
LIG_LIR_Nem_3 122 128 PF02991 0.399
LIG_PDZ_Class_2 133 138 PF00595 0.679
LIG_SH2_CRK 76 80 PF00017 0.634
LIG_SH2_STAT5 119 122 PF00017 0.324
LIG_SH2_STAT5 20 23 PF00017 0.484
LIG_SH2_STAT5 86 89 PF00017 0.505
LIG_SH2_STAT5 98 101 PF00017 0.312
MOD_CK1_1 22 28 PF00069 0.359
MOD_CK2_1 50 56 PF00069 0.757
MOD_CK2_1 98 104 PF00069 0.324
MOD_GlcNHglycan 21 24 PF01048 0.414
MOD_GlcNHglycan 91 94 PF01048 0.352
MOD_GSK3_1 19 26 PF00069 0.359
MOD_GSK3_1 89 96 PF00069 0.324
MOD_NEK2_1 126 131 PF00069 0.332
MOD_NEK2_2 23 28 PF00069 0.349
MOD_NEK2_2 93 98 PF00069 0.324
MOD_Plk_4 126 132 PF00069 0.399
MOD_Plk_4 23 29 PF00069 0.377
MOD_Plk_4 93 99 PF00069 0.324
TRG_ENDOCYTIC_2 76 79 PF00928 0.633
TRG_ENDOCYTIC_2 8 11 PF00928 0.447
TRG_ER_diArg_1 41 44 PF00400 0.649
TRG_ER_diArg_1 47 49 PF00400 0.630

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IHP8 Leishmania donovani 79% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS