Arrestin_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

E9AEM2_LEIMA

TriTrypDb:

LmjF.35.0450 , LMJLV39_350009800 , LMJSD75_350009700

Length:

603

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AEM2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AEM2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	365	369	PF00656	0.600
CLV_NRD_NRD_1	96	98	PF00675	0.652
CLV_PCSK_KEX2_1	241	243	PF00082	0.792
CLV_PCSK_KEX2_1	285	287	PF00082	0.752
CLV_PCSK_KEX2_1	416	418	PF00082	0.603
CLV_PCSK_KEX2_1	55	57	PF00082	0.658
CLV_PCSK_KEX2_1	96	98	PF00082	0.652
CLV_PCSK_PC1ET2_1	241	243	PF00082	0.666
CLV_PCSK_PC1ET2_1	285	287	PF00082	0.612
CLV_PCSK_PC1ET2_1	416	418	PF00082	0.603

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IP18	Leishmania donovani	90%	100%
A4IAU4	Leishmania infantum	90%	100%
E9B5T1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

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