Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

E9AEJ1_LEIMA

TriTrypDb:

LmjF.35.0140 , LMJLV39_350006400 , LMJSD75_350006500

Length:

119


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

E9AEJ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AEJ1


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.622
CLV_NRD_NRD_1	3	5	PF00675	0.433
CLV_NRD_NRD_1	32	34	PF00675	0.410
CLV_PCSK_KEX2_1	3	5	PF00082	0.433
CLV_PCSK_KEX2_1	31	33	PF00082	0.409
CLV_PCSK_KEX2_1	45	47	PF00082	0.394
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.409
CLV_PCSK_PC1ET2_1	45	47	PF00082	0.394
CLV_PCSK_PC7_1	27	33	PF00082	0.413
CLV_PCSK_SKI1_1	4	8	PF00082	0.471
DEG_Nend_Nbox_1	1	3	PF02207	0.672
DOC_USP7_MATH_1	38	42	PF00917	0.711
LIG_14-3-3_CanoR_1	3	7	PF00244	0.682
LIG_14-3-3_CanoR_1	60	67	PF00244	0.574
LIG_EH1_1	86	94	PF00400	0.368
LIG_LIR_Gen_1	58	67	PF02991	0.579
LIG_LIR_Gen_1	79	90	PF02991	0.335
LIG_LIR_Nem_3	58	64	PF02991	0.571
LIG_LIR_Nem_3	69	73	PF02991	0.553
LIG_LIR_Nem_3	79	85	PF02991	0.335
LIG_Pex14_2	48	52	PF04695	0.591
LIG_SH2_CRK	82	86	PF00017	0.335
LIG_SH2_NCK_1	82	86	PF00017	0.480
LIG_SH2_SRC	109	112	PF00017	0.445
LIG_SH2_STAP1	109	113	PF00017	0.342
LIG_SH2_STAP1	61	65	PF00017	0.572
LIG_SH2_STAT5	70	73	PF00017	0.621
LIG_SH2_STAT5	88	91	PF00017	0.335
LIG_SH3_3	12	18	PF00018	0.643
LIG_UBA3_1	95	104	PF00899	0.458
MOD_CK1_1	72	78	PF00069	0.561
MOD_CMANNOS	77	80	PF00535	0.357
MOD_GSK3_1	72	79	PF00069	0.561
MOD_N-GLC_1	48	53	PF02516	0.438
MOD_NEK2_1	2	7	PF00069	0.636
MOD_NEK2_2	109	114	PF00069	0.447
MOD_PKA_2	2	8	PF00069	0.642
MOD_PKA_2	59	65	PF00069	0.578
MOD_Plk_1	109	115	PF00069	0.449
MOD_Plk_1	48	54	PF00069	0.636
MOD_Plk_4	18	24	PF00069	0.716
MOD_Plk_4	76	82	PF00069	0.482
MOD_Plk_4	88	94	PF00069	0.316
TRG_ENDOCYTIC_2	61	64	PF00928	0.566
TRG_ENDOCYTIC_2	70	73	PF00928	0.542
TRG_ENDOCYTIC_2	82	85	PF00928	0.312
TRG_ER_diArg_1	2	4	PF00400	0.639
TRG_ER_diArg_1	32	34	PF00400	0.610
TRG_Pf-PMV_PEXEL_1	32	37	PF00026	0.412


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5M2	Leptomonas seymouri	90%	100%
A0A1X0NJM2	Trypanosomatidae	79%	100%
A0A3S7X8W1	Leishmania donovani	98%	100%
A0A422N7I5	Trypanosoma rangeli	79%	99%
A4HM53	Leishmania braziliensis	97%	100%
A4IAR5	Leishmania infantum	98%	100%
D0A2E7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	77%	99%
E9B5Q2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
V5BNC2	Trypanosoma cruzi	73%	99%